TY  - JOUR
TI  - COVID-19 experience of the major pandemic response center in the capital: results of
the pandemic’s first month in Turkey
AB  - Background/aim: The aim of this study is to evaluate the epidemiological and clinical characteristics and parameters that determined the
clinical course and prognosis of the COVID-19 patients admitted to Ankara City Hospital during the first month of the pandemic in Turkey.
Materials and methods: SARS-CoV-2 PCR positive patients who were hospitalized between March 10 and April 10, 2020 were included.
Results: Among 222 patients, mean age was higher in severe acute respiratory illness (SARI)/critical disease group (P < 0.001). Median time
from illness onset to admission and presence of comorbidity, especially coronary artery disease and chronic obstructive pulmonary disease,
were significantly higher in the SARI/critical disease group (P < 0.05). Cough and fever were the most common symptoms, while anosmia
and loss of taste were observed in 8.6% and 7.7% patients, respectively. The mortality rate was 5.4%. A high neutrophil/lymphocyte ratio;
low lymphocyte, monocyte, and platelet count; elevated liver enzymes; low GFR; and high levels of muscle enzymes, ferritin, and IL-6 on
admission were found to be associated with SARI/critical disease (P < 0.05). Bilateral ground-glass opacity and patchy infiltration were more
frequently seen in the SARI/critical disease group (P < 0.001). Patients older than 65 years had an 8-fold increased risk for development of
SARI/critical disease.
Conclusion: This cohort study regarding COVID-19 cases in Turkey reveals that older age, presence of comorbidity, bilateral infiltration on
CT, high neutrophil/lymphocyte ratio, low monocyte and platelet count, elevated liver enzymes, low GFR, high levels of muscle enzymes,
and high levels of ferritin and IL-6 on admission are predictors of SARI and severe disease.




Ankara Şehir Hastanesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Ankara, Türkiye
AU  - Altunsoy, Adalet
AU  - Ayhan, Müge
AU  - dinc, bedia
AU  - Mutlu, Nevzat Mehmet
AU  - Erdem, Deniz
AU  - eser, fatma
AU  - Kaya Kalem, Ayse
AU  - Kayaaslan, Bircan
AU  - Hasanoglu, Imran
AU  - BUZGAN, TURAN
AU  - Sarıcaoğlu, Elif mukime
AU  - Akıncı, Esragül
AU  - OZDEMIR, BURCU
AU  - aybar bilir, yeşim
AU  - GÜNER, RAHMET
AU  - özkoçak turan, ışıl
DO  - 10.3906/sag-2006-164
PY  - 2020
JO  - Turkish Journal of Medical Sciences
VL  - 50
IS  - 8
SN  - 1300-0144
SP  - 1801
EP  - 1809
DB  - TRDizin
UR  - http://search/yayin/detay/535646
ER  -