TY  - JOUR
TI  - Role of first trimester screening test in predicting the
perinatal outcomes in low risk term pregnancies
AB  - Objective: This study aims to investigate the relationship between the nuchal translucency (NT) values measured in the first trimester and the
well-being of the newborn.
Methods: The study was planned as a retrospective cross-sectional study and was conducted between January 2018 and January 2020. A total of
2394 patients who had a combined test and delivered at our university hospital were included in the study. The demographic data of the pregnant
women were recorded. NT MoM values, PAPP-A and β-hCG MoM values, birth weight, gender, need for neonatal intensive care (NICU), and
Apgar scores were evaluated.
Results: It was found that NT (MoM) values were similar among the SGA, AGA, and LGA groups (p=0.159). PAPP-A (MoM) values were similar
in the SGA group compared to AGA and LGA infant groups (p=0.947). It was also found that β-hCG (MoM) values were similar in the AGA
group compared to SGA and the LGA infant groups (p=0.694). When compared with those with NICU and non-NICU, the NT, PAPP-A, β-
hCG, and birth weight values were again not found to be statistically significant (p>0.05). The NT, PAPP-A, β-hCG, and male gender factors
were evaluated in the Binary Logistic Regression Analysis, in which being an SGA baby was considered as a risk. It was found that a 1 mm
increase in NT values increased the risk of having an SGA baby 2.63 times at a statistically significant level (OR=2.636, p=0.009, 95% CI:
1.277–5.440). PAPP-A, β-hCG levels, and having a male gender were not related to the risk of having an SGA baby. Furthermore, NT, PAPPA,
β-hCG levels, and having a male gender were not associated with the risk of NICU hospitalization.
Conclusion: In conclusion, we could not predict the birth weight with increased NT MoM values that were detected in the first trimester
combined test in this study; however, we found that the risk of having an SGA fetus increases with a weak rise in NT value.
AU  - Bayram, Merih
AU  - Akbarihamed, Roujin
AU  - Özdemir, Halis
AU  - Turan, Gökçe
AU  - Turgut, Ezgi
AU  - KARÇAALTINCABA, DENIZ
AU  - Konca, Sibel
DO  - 10.2399/prn.22.0302008
PY  - 2022
JO  - Perinatal journal (Online)
VL  - 30
IS  - 2
SN  - 1305-3124
SP  - 152
EP  - 157
DB  - TRDizin
UR  - http://search/yayin/detay/536151
ER  -