Yıl: 2022 Cilt: 52 Sayı: 3 Sayfa Aralığı: 541 - 546 Metin Dili: İngilizce DOI: 10.55730/1300-0144.5344 İndeks Tarihi: 26-07-2022

Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey

Öz:
Background/aim: CoronaVac is an inactivated virus-based COVID-19 vaccine used in Turkey and approved for emergency use by the World Health Organization (WHO). In this study, it was aimed to retrospectively evaluate the mutation status and clinical status in individuals who received two doses of CoronaVac vaccine and were infected with COVID-19 at least two weeks after the second dose. Materials and methods: 164 people were included in the study and COVID-19 diagnosis and mutation analyses were determined by RT-PCR using the Bioseepdy SARS CoV-2 Double Gene RT-qPCR Kit and the Biospeedy SARS-CoV-2 Variant Plus kit in accordance with the protocol determined by the manufacturer. Results: 116 (70.7%) UK (Alpha, B.1.1.7) mutation and 3 (1.8%) South Africa (Beta, B.1.351), Brazil (Gamma, P.1) mutations were determined in 164 double doses CoronaVac vaccinated patients; 45 (27.5%) patients were mutation negative. Nine patients (5.5%) developed pneumonia. Eight patients (4.9%) had CT findings compatible with corona virus infection. Seven (4.3%) of the patients received treatment in the intensive care unit, and 5 (3%) of the patients were intubated. Conclusions: In conclusion, people who receive two doses of CoronaVac vaccine can be reinfected with mutant viruses, vaccine significantly reduces the need for hospitalization, CT findings and intensive care.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Çalışkan A, Seçme M, Kaleli İ, Sari T, Öner S, Küçükakın Yaka S, DÖNMEZ B (2022). Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey. , 541 - 546. 10.55730/1300-0144.5344
Chicago Çalışkan Ahmet,Seçme Mücahit,Kaleli İlknur,Sari Tugba,Öner Sedef Zeliha,Küçükakın Yaka Saniye,DÖNMEZ BÜŞRA Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey. (2022): 541 - 546. 10.55730/1300-0144.5344
MLA Çalışkan Ahmet,Seçme Mücahit,Kaleli İlknur,Sari Tugba,Öner Sedef Zeliha,Küçükakın Yaka Saniye,DÖNMEZ BÜŞRA Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey. , 2022, ss.541 - 546. 10.55730/1300-0144.5344
AMA Çalışkan A,Seçme M,Kaleli İ,Sari T,Öner S,Küçükakın Yaka S,DÖNMEZ B Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey. . 2022; 541 - 546. 10.55730/1300-0144.5344
Vancouver Çalışkan A,Seçme M,Kaleli İ,Sari T,Öner S,Küçükakın Yaka S,DÖNMEZ B Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey. . 2022; 541 - 546. 10.55730/1300-0144.5344
IEEE Çalışkan A,Seçme M,Kaleli İ,Sari T,Öner S,Küçükakın Yaka S,DÖNMEZ B "Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey." , ss.541 - 546, 2022. 10.55730/1300-0144.5344
ISNAD Çalışkan, Ahmet vd. "Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey". (2022), 541-546. https://doi.org/10.55730/1300-0144.5344
APA Çalışkan A, Seçme M, Kaleli İ, Sari T, Öner S, Küçükakın Yaka S, DÖNMEZ B (2022). Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey. Turkish Journal of Medical Sciences, 52(3), 541 - 546. 10.55730/1300-0144.5344
Chicago Çalışkan Ahmet,Seçme Mücahit,Kaleli İlknur,Sari Tugba,Öner Sedef Zeliha,Küçükakın Yaka Saniye,DÖNMEZ BÜŞRA Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey. Turkish Journal of Medical Sciences 52, no.3 (2022): 541 - 546. 10.55730/1300-0144.5344
MLA Çalışkan Ahmet,Seçme Mücahit,Kaleli İlknur,Sari Tugba,Öner Sedef Zeliha,Küçükakın Yaka Saniye,DÖNMEZ BÜŞRA Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey. Turkish Journal of Medical Sciences, vol.52, no.3, 2022, ss.541 - 546. 10.55730/1300-0144.5344
AMA Çalışkan A,Seçme M,Kaleli İ,Sari T,Öner S,Küçükakın Yaka S,DÖNMEZ B Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey. Turkish Journal of Medical Sciences. 2022; 52(3): 541 - 546. 10.55730/1300-0144.5344
Vancouver Çalışkan A,Seçme M,Kaleli İ,Sari T,Öner S,Küçükakın Yaka S,DÖNMEZ B Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey. Turkish Journal of Medical Sciences. 2022; 52(3): 541 - 546. 10.55730/1300-0144.5344
IEEE Çalışkan A,Seçme M,Kaleli İ,Sari T,Öner S,Küçükakın Yaka S,DÖNMEZ B "Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey." Turkish Journal of Medical Sciences, 52, ss.541 - 546, 2022. 10.55730/1300-0144.5344
ISNAD Çalışkan, Ahmet vd. "Determination of COVID-19 PCR positivity and mutation status in coronaVac vaccinated individuals in Turkey". Turkish Journal of Medical Sciences 52/3 (2022), 541-546. https://doi.org/10.55730/1300-0144.5344