TY  - JOUR
TI  - Effectiveness of a supervised group exercise therapy based on the biopsychosocial model
introduced simultaneously with anti-TNF therapy in anti-TNF-naive patients with active
ankylosing spondylitis
AB  - Background/aim: This study aimed to investigate the effectiveness of a supervised group exercise therapy based on the biopsychosocial
model introduced simultaneously with antitumor necrosis factor (TNF) therapy in anti-TNF-naive patients with active ankylosing
spondylitis (AS).
Materials and methods: Forty-eight patients were divided into two groups: the control group (CG; n = 36) received only anti-TNF
therapy, and the study group (SG; n = 12) received the supervised exercise therapy based on the biopsychosocial model in addition
to anti-TNF therapy. The measurements of disease activity and functionality were evaluated by The Bath AS Disease Activity Index
(BASDAI) and The Bath AS Functional Index (BASFI) respectively. Other outcome measures evaluated biopsychosocial status,
emotional state, spinal mobility, pain, fatigue, sleep, and quality of life. All measurements were applied to both groups at baseline and
repeated 12 weeks later.
Results: BASDAI and BASFI analyses revealed significant differences between groups in favor of the SG (p < 0.05). At the end of the
12 weeks, the results showed that there were additional improvements in all outcome measurement parameters in the SG compared to
the CG.
Conclusion: The supervised group exercise therapy based on the biopsychosocial model introduced simultaneously with anti-TNF
therapy is more effective than only anti-TNF therapy in anti-TNF-naive patients with active AS.
AU  - Ünal, Edibe
AU  - Karaca, Nur Banu
AU  - Karakaya, Jale
AU  - Kalyoncu, Umut
AU  - KİRAZ, SEDAT
DO  - 10.55730/1300-0144.5359
PY  - 2022
JO  - Turkish Journal of Medical Sciences
VL  - 52
IS  - 3
SN  - 1300-0144
SP  - 667
EP  - 676
DB  - TRDizin
UR  - http://search/yayin/detay/536356
ER  -