Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs

TOPLU, Nihat; kokcu ataseven, lale; Tunca, Recai; ÖZEN, Hasan; HAZIROĞLU, Rıfkı; Guvenc, Tolga

Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs

Recai TUNCA, (Kafkas Üniversitesi, Veteriner Fakültesi, Patoloji Anabilim Dalı, Kars, Türkiye)

Tolga GÜVENÇ, (Ondokuz Mayıs Üniversitesi, Veteriner Fakültesi, Samsun, Türkiye)

Rıfkı HAZIROĞLU, (Ankara Üniversitesi, Veteriner Fakültesi, Patoloji Anabilim Dalı, Ankara, Türkiye)

LAle ATASEVEN, (İl Kontrol Laboratuvarı, Van, Türkiye)

Hasan ÖZEN, (Kafkas Üniversitesi, Veteriner Fakültesi, Kars, Türkiye)

Nihat TOPLU (Adnan Menderes Üniversitesi, Veteriner Fakültesi, Aydın, Türkiye)

Turkish Journal of Veterinary and Animal Sciences

1 0

Yıl: 2006 Cilt: 30 Sayı: 6 Sayfa Aralığı: 545 - 551 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs

Öz:

Hayvanlarda sistemik kandidiazis tanısı güç ve az rastlanılan bir hastalıktır. Çalışmada üç köpekte rastlanılan sistemik kandidiazisin klinik seyri, patolojik bulguları ve kültür sonuçları değerlendirilerek hastalığa yatkınlığı arttıran olası faktörler tartışıldı. Patolojik olarak tüm köpeklerde çeşitli organlarda pyogranülomatöz lezyonlar saptandı. Periyodik asit Schiff, Gomori methenamin silver ve immunohistokimyasal boyamalarda Candida albicans'm blastospor, yalancı ve gerçek hifalarından oluşan gelişim formları görüldü. Geniş spektrumlu antibiyotik kullanımı ve bir olguda rastlanılan parvoviral enfeksiyonun fırsatçı kandida enfeksiyonu için hazırlayıcı olduğu düşünüldü. Muhtemelen bu köpeklerde immun baskılanma ve antibiyotik tedavisi Candida kolonizasyonu ve yayılmasına öncülük etmişti.

Anahtar Kelime: ilaç kombinasyonları teşhis Candida albicans kandida enfeksiyonu kortikoidler hastalık kontrolü antibiyotikler köpek predispozisyon immünohistokimya

Konular: Ziraat Mühendisliği

Köpeklerde doğal sistemik Candida albicans enfeksiyonunun patolojik ve immunohistokimyasal yönden değerlendirilmesi

Öz:

Systemic candidiasis is a rare disease of animals. In this study, the clinical course, and cultural and pathological findings of systemic candidiasis are described and presumed predisposing factors are investigated in 3 dogs. Pathologically, pyogranulomatous lesions in various organs were present in all dogs. Blastospores, pseudohyphae, and true hyphae of Candida albicans were observed with periodic acid Schiff, Gomori's methenamine silver, and immunohistochemistry. Administrations of broad-spectrum antibiotics and corticosteroids and, in one dog, parvoviral infection were thought to be predisposing factors leading to opportunistic infection. The combined effect of immunosuppressants and antibiotics might have led to Candida colonization and dissemination in these dogs.

Anahtar Kelime: antibiotics dogs predisposition immunohistochemistry drug combinations diagnosis Candida albicans candidosis corticoids disease control

Konular: Ziraat Mühendisliği

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Tunca R, Guvenc T, HAZIROĞLU R, kokcu ataseven l, ÖZEN H, TOPLU N (2006). Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs. , 545 - 551.
Chicago	Tunca Recai,Guvenc Tolga,HAZIROĞLU Rıfkı,kokcu ataseven lale,ÖZEN Hasan,TOPLU Nihat Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs. (2006): 545 - 551.
MLA	Tunca Recai,Guvenc Tolga,HAZIROĞLU Rıfkı,kokcu ataseven lale,ÖZEN Hasan,TOPLU Nihat Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs. , 2006, ss.545 - 551.
AMA	Tunca R,Guvenc T,HAZIROĞLU R,kokcu ataseven l,ÖZEN H,TOPLU N Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs. . 2006; 545 - 551.
Vancouver	Tunca R,Guvenc T,HAZIROĞLU R,kokcu ataseven l,ÖZEN H,TOPLU N Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs. . 2006; 545 - 551.
IEEE	Tunca R,Guvenc T,HAZIROĞLU R,kokcu ataseven l,ÖZEN H,TOPLU N "Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs." , ss.545 - 551, 2006.
ISNAD	Tunca, Recai vd. "Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs". (2006), 545-551.

APA	Tunca R, Guvenc T, HAZIROĞLU R, kokcu ataseven l, ÖZEN H, TOPLU N (2006). Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs. Turkish Journal of Veterinary and Animal Sciences, 30(6), 545 - 551.
Chicago	Tunca Recai,Guvenc Tolga,HAZIROĞLU Rıfkı,kokcu ataseven lale,ÖZEN Hasan,TOPLU Nihat Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs. Turkish Journal of Veterinary and Animal Sciences 30, no.6 (2006): 545 - 551.
MLA	Tunca Recai,Guvenc Tolga,HAZIROĞLU Rıfkı,kokcu ataseven lale,ÖZEN Hasan,TOPLU Nihat Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs. Turkish Journal of Veterinary and Animal Sciences, vol.30, no.6, 2006, ss.545 - 551.
AMA	Tunca R,Guvenc T,HAZIROĞLU R,kokcu ataseven l,ÖZEN H,TOPLU N Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs. Turkish Journal of Veterinary and Animal Sciences. 2006; 30(6): 545 - 551.
Vancouver	Tunca R,Guvenc T,HAZIROĞLU R,kokcu ataseven l,ÖZEN H,TOPLU N Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs. Turkish Journal of Veterinary and Animal Sciences. 2006; 30(6): 545 - 551.
IEEE	Tunca R,Guvenc T,HAZIROĞLU R,kokcu ataseven l,ÖZEN H,TOPLU N "Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs." Turkish Journal of Veterinary and Animal Sciences, 30, ss.545 - 551, 2006.
ISNAD	Tunca, Recai vd. "Pathological and immunohistochemical investigation of naturally occurring systemic Candida albicans infection in dogs". Turkish Journal of Veterinary and Animal Sciences 30/6 (2006), 545-551.