The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes

ÇETİNKAYA, Burcu Özkan; ŞİMŞEK, Selen Burçak; KELEŞ, Gonca Çayır; Koprulu, Diyar; KAHRAMAN, Hakkı

The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes

Gonca Çayır KELEŞ, (Ondokuz Mayıs Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Anabilim Dalı, Samsun)

Burcu Özkan ÇETİNKAYA, (Ondokuz Mayıs Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Anabilim Dalı, Samsun)

Selen Burçak ŞİMŞEK, (Ondokuz Mayıs Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Anabilim Dalı, Samsun)

Diyar KÖPRÜLÜ, (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Samsun, Türkiye)

Hakkı KAHRAMAN (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Samsun, Türkiye)

Turkish Journal of Medical Sciences

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Yıl: 2007 Cilt: 37 Sayı: 1 Sayfa Aralığı: 39 - 44 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes

Öz:

Aims: Chronic infections such as periodontal disease (PD) have been suggested to be a risk factor for coronary heart disease (CHD). Elevated levels of acute phase proteins are associated with increased risk for cardiovascular events in both healthy individuals and patients with known CHD. This study aimed to investigate the role of PD on C-reactive protein (CRP) and fibrinogen levels in patients with either CHD or type 2 diabetes. Materials and Methods: 80 subjects were evaluated in four groups: individuals with CHD+PD (group 1; n: 20), individuals with type 2 diabetes+PD (group 2; n: 20), individuals with PD without any systemic disease (group 3; n: 20), and healthy individuals (group 4; n: 20). Blood samples were taken at the time of periodontal examination. Results: Demographic characteristics between the four groups and periodontal parameters between groups 1, 2, and 3 were not statistically different (P > 0.05). CRP and fibrinogen levels were increased in groups 1, 2, and 3 compared to those in group 4 (P < 0.05). Conclusions: The patients in groups 1, 2, and 3 may have risk for future cardiovascular events. Findings of the present study seem to indicate that periodontitis contributes to systemic inflammation due to higher CRP and fibrinogen levels. Physicians should be aware that maintaining periodontal health might be effective in reducing cardiovascular events risk in periodontitis subjects with/without CHD and diabetes

Anahtar Kelime:

Konular: Cerrahi

Koroner kalp hastalığı ve diabeti olan bireylerde periodontal hastalığın akut faz proteinleri üzerine etkisi

Öz:

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	KELEŞ G, ÇETİNKAYA B, ŞİMŞEK S, Koprulu D, KAHRAMAN H (2007). The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes. , 39 - 44.
Chicago	KELEŞ Gonca Çayır,ÇETİNKAYA Burcu Özkan,ŞİMŞEK Selen Burçak,Koprulu Diyar,KAHRAMAN Hakkı The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes. (2007): 39 - 44.
MLA	KELEŞ Gonca Çayır,ÇETİNKAYA Burcu Özkan,ŞİMŞEK Selen Burçak,Koprulu Diyar,KAHRAMAN Hakkı The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes. , 2007, ss.39 - 44.
AMA	KELEŞ G,ÇETİNKAYA B,ŞİMŞEK S,Koprulu D,KAHRAMAN H The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes. . 2007; 39 - 44.
Vancouver	KELEŞ G,ÇETİNKAYA B,ŞİMŞEK S,Koprulu D,KAHRAMAN H The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes. . 2007; 39 - 44.
IEEE	KELEŞ G,ÇETİNKAYA B,ŞİMŞEK S,Koprulu D,KAHRAMAN H "The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes." , ss.39 - 44, 2007.
ISNAD	KELEŞ, Gonca Çayır vd. "The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes". (2007), 39-44.

APA	KELEŞ G, ÇETİNKAYA B, ŞİMŞEK S, Koprulu D, KAHRAMAN H (2007). The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes. Turkish Journal of Medical Sciences, 37(1), 39 - 44.
Chicago	KELEŞ Gonca Çayır,ÇETİNKAYA Burcu Özkan,ŞİMŞEK Selen Burçak,Koprulu Diyar,KAHRAMAN Hakkı The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes. Turkish Journal of Medical Sciences 37, no.1 (2007): 39 - 44.
MLA	KELEŞ Gonca Çayır,ÇETİNKAYA Burcu Özkan,ŞİMŞEK Selen Burçak,Koprulu Diyar,KAHRAMAN Hakkı The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes. Turkish Journal of Medical Sciences, vol.37, no.1, 2007, ss.39 - 44.
AMA	KELEŞ G,ÇETİNKAYA B,ŞİMŞEK S,Koprulu D,KAHRAMAN H The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes. Turkish Journal of Medical Sciences. 2007; 37(1): 39 - 44.
Vancouver	KELEŞ G,ÇETİNKAYA B,ŞİMŞEK S,Koprulu D,KAHRAMAN H The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes. Turkish Journal of Medical Sciences. 2007; 37(1): 39 - 44.
IEEE	KELEŞ G,ÇETİNKAYA B,ŞİMŞEK S,Koprulu D,KAHRAMAN H "The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes." Turkish Journal of Medical Sciences, 37, ss.39 - 44, 2007.
ISNAD	KELEŞ, Gonca Çayır vd. "The role of periodontal disease on acute phase proteins in patients with coronary heart disease and diabetes". Turkish Journal of Medical Sciences 37/1 (2007), 39-44.