Yıl: 2007 Cilt: 15 Sayı: 3 Sayfa Aralığı: 153 - 159 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Diabetik retinopatide güncel tıbbi tedavi yaklaşımları

Öz:
Diabetik retinopati (DR), günümüzde gelişmiş toplumlarda körlüğün en önemli nedenidir. Hastalığın süresi uzadıkça komplikasyon riski artmakta ve eşlik eden sistemik faktörler ilerlemesini hızlandırmaktadır. Bu nedenle öncelikle sistemik durumun düzenlenmesi gerekmektedir. Diabetik retinopati tedavisinde lazer fotokoagülasyon ve vitreoretinal cerrahinin yanı sıra son yıllarda medikal tedavide gelişmeler sağlanmıştır. Antioksidanlar, aldoz redüktaz ve ileri glikolizasyon son ürün inhibitörleri, protein kinaz C inhibitörleri, vasküler endotelyal büyüme faktörü (VEGF) inhibitörleri ve intravitreal kortikosteroid enjeksiyonları medikal tedavide kullanılan ajanlardır. Medikal tedavideki gelişmeler ile diabetik retinopati gelişimi ve ilerleyişinin yavaşlatılması sağlanmaktadır.Bu derlemede, güncel literatür bilgileri ışığında diabetik retinopatide tıbbi tedavi yaklaşımları gözden geçirilmiştir.
Anahtar Kelime: Steroidler Diabetik retinopati Vitreus içi enjeksiyon Vasküler endotelyal büyüme faktörleri Aldehit redüktaz Protein kinaz inhibitörleri Triamsinolon asetonit Protein kinaz C

Konular: Göz Hastalıkları

New medical treatment approaches in diabetic retinopathy

Öz:
Diabetic retinopathy (DR) is one of the most important causes of blindness in developed societies. The risk of complications increases by the duration of disease and some coexisting systemic disorders affect the progression. Therefore, first step in the treatment of DR is regulation of systemic risk factors. Although laser photocoagulation and vitreoretinal surgery are the main treatment modalities of DR, medical approaches have advanced, currently. Antioxidants, inhibitors of aldose reductase, advanced glycation end products, protein kinase C and vascular endothelial growth factor (VEGF) inhibitors and intravitreal corticosteroid injections are medical treatment modalities of DR. The advances in medical approaches can retard the development and progression of DR.In this study, new medical treatment approaches were discussed with the review of recent literature.
Anahtar Kelime: Protein Kinase Inhibitors Triamcinolone Acetonide Protein Kinase C Steroids Diabetic Retinopathy Intravitreal Injections Vascular Endothelial Growth Factors Aldehyde Reductase

Konular: Göz Hastalıkları
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Bibliyografik
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APA POLAT B, BATOĞLU F (2007). Diabetik retinopatide güncel tıbbi tedavi yaklaşımları. , 153 - 159.
Chicago POLAT Burcu,BATOĞLU Figen Diabetik retinopatide güncel tıbbi tedavi yaklaşımları. (2007): 153 - 159.
MLA POLAT Burcu,BATOĞLU Figen Diabetik retinopatide güncel tıbbi tedavi yaklaşımları. , 2007, ss.153 - 159.
AMA POLAT B,BATOĞLU F Diabetik retinopatide güncel tıbbi tedavi yaklaşımları. . 2007; 153 - 159.
Vancouver POLAT B,BATOĞLU F Diabetik retinopatide güncel tıbbi tedavi yaklaşımları. . 2007; 153 - 159.
IEEE POLAT B,BATOĞLU F "Diabetik retinopatide güncel tıbbi tedavi yaklaşımları." , ss.153 - 159, 2007.
ISNAD POLAT, Burcu - BATOĞLU, Figen. "Diabetik retinopatide güncel tıbbi tedavi yaklaşımları". (2007), 153-159.
APA POLAT B, BATOĞLU F (2007). Diabetik retinopatide güncel tıbbi tedavi yaklaşımları. Retina-Vitreus, 15(3), 153 - 159.
Chicago POLAT Burcu,BATOĞLU Figen Diabetik retinopatide güncel tıbbi tedavi yaklaşımları. Retina-Vitreus 15, no.3 (2007): 153 - 159.
MLA POLAT Burcu,BATOĞLU Figen Diabetik retinopatide güncel tıbbi tedavi yaklaşımları. Retina-Vitreus, vol.15, no.3, 2007, ss.153 - 159.
AMA POLAT B,BATOĞLU F Diabetik retinopatide güncel tıbbi tedavi yaklaşımları. Retina-Vitreus. 2007; 15(3): 153 - 159.
Vancouver POLAT B,BATOĞLU F Diabetik retinopatide güncel tıbbi tedavi yaklaşımları. Retina-Vitreus. 2007; 15(3): 153 - 159.
IEEE POLAT B,BATOĞLU F "Diabetik retinopatide güncel tıbbi tedavi yaklaşımları." Retina-Vitreus, 15, ss.153 - 159, 2007.
ISNAD POLAT, Burcu - BATOĞLU, Figen. "Diabetik retinopatide güncel tıbbi tedavi yaklaşımları". Retina-Vitreus 15/3 (2007), 153-159.