Cox regression models with nonproportional hazards applied to lung cancer survival data

SÖZER, M. Tekin; ATA TUTKUN, NİHAL

Cox regression models with nonproportional hazards applied to lung cancer survival data

NİHAL ATA TUTKUN, (Hacettepe Üniversitesi, Fen Fakültesi, İstatistik Bölümü, Ankara, Türkiye)

M. Tekin SÖZER (Hacettepe Üniversitesi, Fen Fakültesi, İstatistik Bölümü, Ankara, Türkiye)

Hacettepe Journal of Mathematics and Statistics

1 0

Yıl: 2007 Cilt: 36 Sayı: 2 Sayfa Aralığı: 157 - 167 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Cox regression models with nonproportional hazards applied to lung cancer survival data

Öz:

The Cox regression model, which is widely used for the analysis of treatment and prognostic effects with censored survival data, makes the assumption of constant hazard ratio. In the violation of this assumption, different methods should be used to deal with non-proportionality of hazards. In this study, the stratified Cox regression model and extended Cox regression model, which uses time dependent covariate terms with fixed functions of time are discussed. The results are illustrated by an analysis of lung cancer data in order to compare these methods with respect to Cox regression model in the presence of nonproportional hazards.

Anahtar Kelime:

Konular: Matematik İstatistik ve Olasılık

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ATA TUTKUN N, SÖZER M (2007). Cox regression models with nonproportional hazards applied to lung cancer survival data. , 157 - 167.
Chicago	ATA TUTKUN NİHAL,SÖZER M. Tekin Cox regression models with nonproportional hazards applied to lung cancer survival data. (2007): 157 - 167.
MLA	ATA TUTKUN NİHAL,SÖZER M. Tekin Cox regression models with nonproportional hazards applied to lung cancer survival data. , 2007, ss.157 - 167.
AMA	ATA TUTKUN N,SÖZER M Cox regression models with nonproportional hazards applied to lung cancer survival data. . 2007; 157 - 167.
Vancouver	ATA TUTKUN N,SÖZER M Cox regression models with nonproportional hazards applied to lung cancer survival data. . 2007; 157 - 167.
IEEE	ATA TUTKUN N,SÖZER M "Cox regression models with nonproportional hazards applied to lung cancer survival data." , ss.157 - 167, 2007.
ISNAD	ATA TUTKUN, NİHAL - SÖZER, M. Tekin. "Cox regression models with nonproportional hazards applied to lung cancer survival data". (2007), 157-167.

APA	ATA TUTKUN N, SÖZER M (2007). Cox regression models with nonproportional hazards applied to lung cancer survival data. Hacettepe Journal of Mathematics and Statistics, 36(2), 157 - 167.
Chicago	ATA TUTKUN NİHAL,SÖZER M. Tekin Cox regression models with nonproportional hazards applied to lung cancer survival data. Hacettepe Journal of Mathematics and Statistics 36, no.2 (2007): 157 - 167.
MLA	ATA TUTKUN NİHAL,SÖZER M. Tekin Cox regression models with nonproportional hazards applied to lung cancer survival data. Hacettepe Journal of Mathematics and Statistics, vol.36, no.2, 2007, ss.157 - 167.
AMA	ATA TUTKUN N,SÖZER M Cox regression models with nonproportional hazards applied to lung cancer survival data. Hacettepe Journal of Mathematics and Statistics. 2007; 36(2): 157 - 167.
Vancouver	ATA TUTKUN N,SÖZER M Cox regression models with nonproportional hazards applied to lung cancer survival data. Hacettepe Journal of Mathematics and Statistics. 2007; 36(2): 157 - 167.
IEEE	ATA TUTKUN N,SÖZER M "Cox regression models with nonproportional hazards applied to lung cancer survival data." Hacettepe Journal of Mathematics and Statistics, 36, ss.157 - 167, 2007.
ISNAD	ATA TUTKUN, NİHAL - SÖZER, M. Tekin. "Cox regression models with nonproportional hazards applied to lung cancer survival data". Hacettepe Journal of Mathematics and Statistics 36/2 (2007), 157-167.