Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey

DEMİR, CENGİZ; Dilek, İmdat; ÖNER, Ahmet Faik; Akdeniz, Hayrettin; BAY, Ali

Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey

İmdat DİLEK, (Yüzüncü Yıl Üniversitesi, Tıp Fakültesi, Hematoloji Anabilim Dalı, Van, Türkiye)

Cengiz DEMİR, (Yüzüncü Yıl Üniversitesi, Tıp Fakültesi, Hematoloji Anabilim Dalı, Van, Türkiye)

Ali BAY, (Yüzüncü Yıl Üniversitesi, Tıp Fakültesi, Pediatrik Hematoloji Anabilim Dalı, Van, Türkiye)

Hayrettin AKDENİZ, (Yüzüncü Yıl Üniversitesi, Tıp Fakültesi, İnfeksiyon Hastalıkları Anabilim Dalı, Van, Türkiye)

Ahmet Faik ÖNER (Yüzüncü Yıl Üniversitesi, Tıp Fakültesi, Pediatrik Hematoloji Anabilim Dalı, Van, Türkiye)

Turkish Journal of Hematology

5 0

Yıl: 2007 Cilt: 24 Sayı: 1 Sayfa Aralığı: 4 - 7 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey

Öz:

İnsan bağışıkyetmezlik virusu (HIV), Hepatit B ve Hepatit C virüslerinin neden oduğu infeksiyonlar halen önde gelen en önemli sağlık problemi olmaya devam etmektedir. HBsAg, anti-HCV, anti-HIV ve VDRL gibi tarama testleri kan ürünleri veya kan transfüzyonlarından önce bakılması zorunlu testlerdir. Bu çalışmada, kan merkezimize 9 yıl içinde başvuran dönorler HBsAg, anti-HCV, anti-HIV ve sifiliz seroprevalansı açısından retrospektif olarak değerlendirildi. HBsAg, anti-HCV, anti-HIV ELİSA mikropartikül sistemi ile incelenirken sifiliz antikorları ise sifiliz test cihazı ile tarandı. Toplam 39.002 kişiden 16.602 (%42)’si kadın ve 22.401 (%58)’i de erkekti. HBsAg, tüm donörlerin %2.55’inde pozitif olarak bulunurken, anti-HCV, anti-HIV ve VDRL pozitifliği sıra ile tüm dönorlerin %0.17, %0.036, %0.057’sinde pozitifti. Sonuç olarak bölgemizde yaşayan donörlerdeki HBsAg, anti-HCV, anti-HIV ve VDRL seropozitifliği Türkiye’de bulunan çoğu bölgelerdekinden daha düşük bulundu. Yine de transfüzyondan kaynaklanan riskleri azaltıp sıfıra indirecek her hangi bir tarama metodu bulunmaması nedeni ile, gereksiz transfüzyonlardan kaçınılmasına ve donör seçiminde daha dikkatli davranılmasına ihtiyaç vardır

Anahtar Kelime: Kan vericileri Seropozitivite Enfeksiyöz hastalık bulaşması, dikey Hepatit B yüzey antijenleri Seroprevalans Geriyedönük çalışma Hepatit C antikorları

Konular: Hematoloji

Türkiye’nin doğu bölgesindeki kan donörlerinde HBsAg, anti-HCV, anti-HIV ve VDRL seropozitivite oranları

Öz:

Infections caused by hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency viruses (HIV) remain the leading most important health problems worldwide. Screening tests such as HBsAg, anti-HCV, anti-HIV and VDRL are mandatory tests to look at before transfusion of blood or blood components. In this study, donors who applied to our Blood Center in a nine-year period were retrospectively evaluated with respect to HBsAg, anti-HCV, anti-HIV and syphilis seroprevalence. HBsAg, anti-HCV and anti-HIV were examined by microparticle ELISA system, and syphilis antibodies were screened by a syphilis test device. Of the total 39,002 individuals, 16,601 (42%) were females and 22,401 (58%) were males. HBsAg positivity was found in 2.55%, anti-HCV in 0.17%, anti-HIV in 0.036%, and VDRL in 0.057% of overall donors. As a result, HBsAg, anti-HCV, anti-HIV and VDRL seropositivity rates in donors living in our region were found lower than those in many regions of Turkey. Nevertheless, because there is no screening method to reduce the risk resulting from transfusion to zero, it appears that it is essential to adopt strict criteria in the selection of donors and to avoid unnecessary transfusion.

Anahtar Kelime: Seroprevalance Retrospective Studies Hepatitis C Antibodies Blood Donors Seropositivity Infectious Disease Transmission, Vertical Hepatitis B Surface Antigens

Konular: Hematoloji

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Dilek İ, DEMİR C, BAY A, Akdeniz H, ÖNER A (2007). Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey. , 4 - 7.
Chicago	Dilek İmdat,DEMİR CENGİZ,BAY Ali,Akdeniz Hayrettin,ÖNER Ahmet Faik Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey. (2007): 4 - 7.
MLA	Dilek İmdat,DEMİR CENGİZ,BAY Ali,Akdeniz Hayrettin,ÖNER Ahmet Faik Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey. , 2007, ss.4 - 7.
AMA	Dilek İ,DEMİR C,BAY A,Akdeniz H,ÖNER A Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey. . 2007; 4 - 7.
Vancouver	Dilek İ,DEMİR C,BAY A,Akdeniz H,ÖNER A Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey. . 2007; 4 - 7.
IEEE	Dilek İ,DEMİR C,BAY A,Akdeniz H,ÖNER A "Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey." , ss.4 - 7, 2007.
ISNAD	Dilek, İmdat vd. "Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey". (2007), 4-7.

APA	Dilek İ, DEMİR C, BAY A, Akdeniz H, ÖNER A (2007). Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey. Turkish Journal of Hematology, 24(1), 4 - 7.
Chicago	Dilek İmdat,DEMİR CENGİZ,BAY Ali,Akdeniz Hayrettin,ÖNER Ahmet Faik Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey. Turkish Journal of Hematology 24, no.1 (2007): 4 - 7.
MLA	Dilek İmdat,DEMİR CENGİZ,BAY Ali,Akdeniz Hayrettin,ÖNER Ahmet Faik Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey. Turkish Journal of Hematology, vol.24, no.1, 2007, ss.4 - 7.
AMA	Dilek İ,DEMİR C,BAY A,Akdeniz H,ÖNER A Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey. Turkish Journal of Hematology. 2007; 24(1): 4 - 7.
Vancouver	Dilek İ,DEMİR C,BAY A,Akdeniz H,ÖNER A Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey. Turkish Journal of Hematology. 2007; 24(1): 4 - 7.
IEEE	Dilek İ,DEMİR C,BAY A,Akdeniz H,ÖNER A "Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey." Turkish Journal of Hematology, 24, ss.4 - 7, 2007.
ISNAD	Dilek, İmdat vd. "Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey". Turkish Journal of Hematology 24/1 (2007), 4-7.