Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case

REŞORLU, Berkan; Baltacı, Sümer; Savas, Berna; REŞORLU, Mustafa; KANKAYA, Duygu

Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case

Berkan REŞORLU, (Ankara Üniversitesi, Tıp Fakültesi, Üroloji Anabilim Dalı, Ankara, Türkiye)

Sümer BALTACI, (Ankara Üniversitesi, Tıp Fakültesi, Üroloji Anabilim Dalı, Ankara, Türkiye)

Mustafa REŞORLU, (İzmir Eğitim ve Araştırma Hastanesi, Radyoloji Kliniği, İzmir, Türkiye)

Duygu KANKAYA, (Ankara Üniversitesi, Tıp Fakültesi, Patoloji Anabilim Dalı, Ankara, Türkiye)

Berna SAVAŞ (Ankara Üniversitesi, Tıp Fakültesi, Patoloji Anabilim Dalı, Ankara, Türkiye)

Turkish Journal of Gastroenterology

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Yıl: 2007 Cilt: 18 Sayı: 1 Sayfa Aralığı: 47 - 49 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case

Öz:

Gastrointestinal stromal tümörler sindirim sisteminin nadir görülen tümörleridir ve sıklıkla mide veya incebarsaktan, nadiren ise özefagus ve kolondan köken alırlar. Bu tümörler birer reseptör tirozin kinaz molekülü olan c-MET ve c-KIT protoonkogenlerinde meydana gelen mutasyonlar sonucu papiller renal hücreli kanser ile birlikte ailesel kanserler şeklinde karşımıza çıkabilmektedirler. Ancak bazen bu iki tümör sporadik vakalar olarak bir arada bulunabilmektedir ve bu durum bazı yazarlarca gastrointestinal stromal tümör tedavisinde kullanılan imatinib mesylate (gleveec)’ın sekonder tümörlere özellikle de papiller renal hücreli kansere yol açma potansiyeline bağlanmı ştır. Biz bu yazımızda metastatik gastrointestinal tümörü olan bir hastanın bu dönemde ortaya çıkıp gleevec tedavisi sı- rasında ilerleme gösteren papiller renal hücreli kanser ile birlikteliğ ini sunmaktayız.

Anahtar Kelime: Antineoplastik ajanlar Böbrek neoplazmları Piperazinler Neoplazmlar, multipl primer Gastrointestinal stromal tümörler imatinib Nefrektomi Erkek Orta yaşlı Pirimidinler Karsinom, papiller Karsinom, renal hücreli

Konular: Cerrahi

Papiller renal hücreli kanser ve gastrointestinal stromal tümör birlikteliği

Öz:

Gastrointestinal stromal tumors are rare causes of gastrointestinal bleeding. In most cases, these tumors are localized in the stomach and small intestine, more rarely in the esophagus and colon. Papillary renal cell carcinoma and gastrointestinal stromal tumor may occur as recurrent familial tumors related to mutations in the protooncogenes, c-MET and c-KIT, both of which are tyrosine kinase receptor molecules. However, these two tumors can sometimes occur simultaneously in sporadic cases. Some authors blame imatinib mesylate (Gleevec), which is traditionally used in gastrointestinal stromal tumor therapy, as the etiological factor in certain secondary tumors, especially papillary renal cell cancer. In this paper, we present the appearance and growth of papillary renal cell carcinoma in a patient receiving Gleevec therapy for gastrointestinal stromal tumor

Anahtar Kelime: imatinib Nephrectomy Male Middle Aged Pyrimidines Carcinoma, Papillary Carcinoma, Renal Cell Antineoplastic Agents Kidney Neoplasms Piperazines Neoplasms, Multiple Primary Gastrointestinal Stromal Tumors

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık

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APA	REŞORLU B, Baltacı S, REŞORLU M, KANKAYA D, Savas B (2007). Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case. , 47 - 49.
Chicago	REŞORLU Berkan,Baltacı Sümer,REŞORLU Mustafa,KANKAYA Duygu,Savas Berna Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case. (2007): 47 - 49.
MLA	REŞORLU Berkan,Baltacı Sümer,REŞORLU Mustafa,KANKAYA Duygu,Savas Berna Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case. , 2007, ss.47 - 49.
AMA	REŞORLU B,Baltacı S,REŞORLU M,KANKAYA D,Savas B Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case. . 2007; 47 - 49.
Vancouver	REŞORLU B,Baltacı S,REŞORLU M,KANKAYA D,Savas B Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case. . 2007; 47 - 49.
IEEE	REŞORLU B,Baltacı S,REŞORLU M,KANKAYA D,Savas B "Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case." , ss.47 - 49, 2007.
ISNAD	REŞORLU, Berkan vd. "Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case". (2007), 47-49.

APA	REŞORLU B, Baltacı S, REŞORLU M, KANKAYA D, Savas B (2007). Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case. Turkish Journal of Gastroenterology, 18(1), 47 - 49.
Chicago	REŞORLU Berkan,Baltacı Sümer,REŞORLU Mustafa,KANKAYA Duygu,Savas Berna Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case. Turkish Journal of Gastroenterology 18, no.1 (2007): 47 - 49.
MLA	REŞORLU Berkan,Baltacı Sümer,REŞORLU Mustafa,KANKAYA Duygu,Savas Berna Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case. Turkish Journal of Gastroenterology, vol.18, no.1, 2007, ss.47 - 49.
AMA	REŞORLU B,Baltacı S,REŞORLU M,KANKAYA D,Savas B Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case. Turkish Journal of Gastroenterology. 2007; 18(1): 47 - 49.
Vancouver	REŞORLU B,Baltacı S,REŞORLU M,KANKAYA D,Savas B Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case. Turkish Journal of Gastroenterology. 2007; 18(1): 47 - 49.
IEEE	REŞORLU B,Baltacı S,REŞORLU M,KANKAYA D,Savas B "Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case." Turkish Journal of Gastroenterology, 18, ss.47 - 49, 2007.
ISNAD	REŞORLU, Berkan vd. "Coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor in a case". Turkish Journal of Gastroenterology 18/1 (2007), 47-49.