Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens

CHEN, Kuan-wei; GAO, Yu-shi; LI, Hui-fang; WU, Xu; ZHU, Wen-qi; TANG, Qing-ping

Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens

Hui-fang LI, (Inst. of Poultry Science, Chinese Academy of Agriculture Science, Yangzhou 225003-CHINA)

Wen-qi ZHU, (Inst. of Poultry Science, Chinese Academy of Agriculture Science, Yangzhou 225003-CHINA)

Kuan-wei CHEN, (Inst. of Poultry Science, Chinese Academy of Agriculture Science, Yangzhou 225003-CHINA)

Xu WU, (College of Animal Science and Technology, Yangzhou UnivercityYangzhou., China)

Qing-ping TANG, (Inst. of Poultry Science, Chinese Academy of Agriculture Science, Yangzhou 225003-CHINA)

Yu-shi GAO (Inst. of Poultry Science, Chinese Academy of Agriculture Science, Yangzhou 225003-CHINA)

Turkish Journal of Veterinary and Animal Sciences

3 0

Yıl: 2008 Cilt: 32 Sayı: 4 Sayfa Aralığı: 281 - 285 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens

Öz:

Alleles of physiological candidate genes for reproductive traits, insulin-like growth factor-1 (IGF-1), and growth hormone receptor (GHR) were assessed to determine their associations with total egg production (NE), average days of continual egg-laying (ADCE), and number of double yolk eggs (DYE) in Wenchang chickens (Chinese indigenous breed). PCR-RFLP was used for genotype identification. The frequency of restriction enzyme C1/C2 alleles in the population was 0.53 (C1) and 0.47 (C2) for IGF-1. For GHRintron 2 it was 0.06 and 0.94 for (A1) and (A2), respectively, while for GHR-intron 5 it was 0.20 (B1) and 0.80 (B2). Four significant associations were found (P < 0.05): between IGF-1 polymorphism, and NE (300 d), NE (400 d), and ADCE, and between GHR polymorphism and DYE. Two significant effects were observed: for IGF-1 and NE (300 d), and for GHR intron 2 and DYE. The current research supports the effects of GHR and IGF-1 genes on the reproductive traits of chickens.

Anahtar Kelime: genetic polymorphism introns genes alleles laying performance somatotropin insulin-like growth factor enzymes reproductive performance poultry egg production reproductive traits

Konular: Ziraat Mühendisliği

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. Rothschild, M.F., Soller, M.: Candidate gene analysis to detect genes controlling traits of economic importance in domestic livestock. Probe., 1997; 8: 13-20
2. Nagaraja, S.C., Aggrey, S.E., Yao, J., Zadworny, D., Fairfull, R.W., Kuhnlein, U.: Trait association of a genetic marker near the IGF-1 gene in egg-laying chickens. J. Hered., 2000; 91: 150- 156.
3. Chase, C.C. Jr., Kirby, C.J, Hammond, A.C., Olson, T.A., Lucy, M.C.: Patterns of ovarian growth and development in cattle with a growth hormone receptor deficiency. J. Anim. Sci., 1998; 76: 212-219.
4. Feng, X.P, Kuhnlein, U., Aggrey, S.E., Gavora, J.S., Zadworny, D.: Trait association of genetic markers in the growth hormone and the growth hormone receptor gene in a White Leghorn strain. Poult. Sci., 1997; 76: 1770-1775.
5. Kocamis, H., Kirkpatrick-Keller, D.C., Klandorf, H., Killefer, J.: In ovo administration of recombinant human insulin-like growth factor-1 alters postnatal growth and development of broiler chicken. Poult. Sci., 1998; 77: 1913-1919.
6. Roberts, R.D, Sharp, P.J, Burt, D.W, Goddard, C.: Insulin-like growth factor-1 in the ovary of the laying hen: gene expression and biological actions on granulosa and thecal cell. Gen. Comp. Endocrinol., 1994; 93: 327-336.
7. Monget, P., Fabre, S., Mulsant, P., Lecerf, F., Elsen, J.M., Mazerbourg, S., Pisselet, C., Monniaux, D.: Regulation of ovarian folliculogenesis by IGF and BMP system in domestic animals. Domest. Anim. Endocrinol., 2002; 23: 139-154.
8. Ballard, F.J., Johnson, R.J., Owens, P.C., Francis, G.L., Upton, F.M., McMurtry, J.P., Wallace, J.C.: Chicken insulin-like growth factor-1: amino acid sequence, radioimmunoassay, and plasma levels between strains and during growth. Gen. Comp. Endocrinol., 1990; 79: 459-468.
9. Ge, W., Davis, M.E., Hines, H.C., Irvin, K.M., Simmen, R.C.M.: Association of a genetic marker with blood serum insulin-like growth factor-1 concentration and growth trains in Angus cattle. J. Anim. Sci., 2001; 79: 1757-1762.
10. Beccavin, C., Chevalier, B., Cogburn, L.A., Simon, J., Duclos, M.J.: Insulin-like growth factors and body growth in chickens divergently selected for high or low growth rate. J. Endocrinol., 2001; 168: 297-306.
11. King, J.C.: Physiology of pregnancy and nutrient metabolism, Am. J. Clin. Nutr., 2000; 71: 1218-1225.
12. Harvey, S., Hull, K.L.: Growth hormone. A paracrine growth factor? Endocrine, 1997; 7: 267-279.
13. Hocking, P.M., Bernard, R., Wilkie, R.S., Goddard, C.: Plasma growth hormone and insulin-like growth factor-1 (IGF-1) concentrations at the onset of lay in ad libitum and restricted broiler breeder fowl. Br. Poult. Sci., 1994; 35: 299-308.
14. Feng, X.P, Kuhnlein, U., Fairfull, W.R, Aggrey, S.E, Yao, J., Zadworny, D.: A genetic marker in the growth hormone receptor gene associated with body weight in chickens. J. Hered.,1998; 89: 355-359.
15. Kuhnlein, U., Ni, L., Weigend, S, Gavora, J.S, Fairfull, W., Zadworny, D.: DNA polymorphisms in the chicken growth hormone gene: response to selection for disease resistance and association with egg production. Anim. Genet., 1997; 28: 116- 123.
16. National Research Council: Nutrient Requirements of Poultry. National Academy Press, Washington, DC. 1994.
17. Dunn, I.C, Miao, Y.W., Morris, A., Romanov, M.N., Wilson, P.W., Waddington, D.: A study of association between genetic markers in candidate genes and reproductive traits in one generation of a commercial broiler breeder hen population. Heredity, 2004; 92: 128-134.
18. Bruggeman, V., Vanmontfort, D., Renaville, R., Portetelle, D., Decuypere, E.: The effect of food intake from two weeks of age to sexual maturity on plasma growth hormone, insulin-like growth factor-1, insulin-like growth factor-binding proteins and thyroid hormones in female broiler breeder chickens. Gen. Comp. Endocrinol., 1997; 107: 212-220.
19. Decuypere, E., Huybrechts, L.M., Kühn, E.R., Tixier-Boichard, M., Mérat, P.: Physiological alterations associated with the chicken sex-linked dwarfing gene. Crit. Rev. Poult. Biol., 1991; 3: 191- 221.
20. Williams, J., Sharp, P.J., Goddard, C.: The effects of growth hormone on ovarian follicular growth in the domestic hen. J. Reprod. Fertil. Abstr. Ser., 1992; 9: 59.

APA	LI H, ZHU W, CHEN K, WU X, TANG Q, GAO Y (2008). Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens. , 281 - 285.
Chicago	LI Hui-fang,ZHU Wen-qi,CHEN Kuan-wei,WU Xu,TANG Qing-ping,GAO Yu-shi Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens. (2008): 281 - 285.
MLA	LI Hui-fang,ZHU Wen-qi,CHEN Kuan-wei,WU Xu,TANG Qing-ping,GAO Yu-shi Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens. , 2008, ss.281 - 285.
AMA	LI H,ZHU W,CHEN K,WU X,TANG Q,GAO Y Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens. . 2008; 281 - 285.
Vancouver	LI H,ZHU W,CHEN K,WU X,TANG Q,GAO Y Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens. . 2008; 281 - 285.
IEEE	LI H,ZHU W,CHEN K,WU X,TANG Q,GAO Y "Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens." , ss.281 - 285, 2008.
ISNAD	LI, Hui-fang vd. "Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens". (2008), 281-285.

APA	LI H, ZHU W, CHEN K, WU X, TANG Q, GAO Y (2008). Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens. Turkish Journal of Veterinary and Animal Sciences, 32(4), 281 - 285.
Chicago	LI Hui-fang,ZHU Wen-qi,CHEN Kuan-wei,WU Xu,TANG Qing-ping,GAO Yu-shi Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens. Turkish Journal of Veterinary and Animal Sciences 32, no.4 (2008): 281 - 285.
MLA	LI Hui-fang,ZHU Wen-qi,CHEN Kuan-wei,WU Xu,TANG Qing-ping,GAO Yu-shi Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens. Turkish Journal of Veterinary and Animal Sciences, vol.32, no.4, 2008, ss.281 - 285.
AMA	LI H,ZHU W,CHEN K,WU X,TANG Q,GAO Y Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens. Turkish Journal of Veterinary and Animal Sciences. 2008; 32(4): 281 - 285.
Vancouver	LI H,ZHU W,CHEN K,WU X,TANG Q,GAO Y Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens. Turkish Journal of Veterinary and Animal Sciences. 2008; 32(4): 281 - 285.
IEEE	LI H,ZHU W,CHEN K,WU X,TANG Q,GAO Y "Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens." Turkish Journal of Veterinary and Animal Sciences, 32, ss.281 - 285, 2008.
ISNAD	LI, Hui-fang vd. "Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in wenchang chickens". Turkish Journal of Veterinary and Animal Sciences 32/4 (2008), 281-285.