The antioxidant activity of some medicinal plants

RAVICHANDRAN, Veerasamy; JAIN, Prateek Kumar; SHARMA, Simant; AGRAWAL, Ram K.

The antioxidant activity of some medicinal plants

Prateek Kumar JAIN, (Department, of Pharmaceutical Sciences, Dr. Hari Singh Gour Univercity, Sagar (M.P.), 470 003-India)

Veerasamy RAVICHANDRAN, (Department, of Pharmaceutical Sciences, Dr. Hari Singh Gour Univercity, Sagar (M.P.), 470 003-India)

Simant SHARMA, (Department, of Pharmaceutical Sciences, Dr. Hari Singh Gour Univercity, Sagar (M.P.), 470 003-India)

Ram K. AGRAWAL (Department, of Pharmaceutical Sciences, Dr. Hari Singh Gour Univercity, Sagar (M.P.), 470 003-India)

Turkish Journal of Biology

8 0

Yıl: 2008 Cilt: 32 Sayı: 3 Sayfa Aralığı: 197 - 202 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The antioxidant activity of some medicinal plants

Öz:

DPPH (1,1-difenil-2-pikril hidrazil) testi, hidroksil süpürücü test ve lipid peroksidasyon testi ile 10 farklı bitkinin antioksidant aktiviteleri incelenmiştir. Emblica officinalis bitkisinin metanol özütü DPPH denemsinde IC50 7,92 ± 0,1 μg/ml ile çok aktif bulunmuştur. Bu bitkiyi, IC50 değeri 9,28 ± 0,2 μg/ml ile Asparagus racemosus takip etmiştir. En az serbest radikal süpürücü etkiyi IC50 değeri 44,48 ± 1,8 μg/ml ile Zingiber officinale bitkisi göstermiştir. Metanolik özütün hidroksil süpürücü etkisine gore bitkiler Asparagus racemosus > Terminalia chebula > Emblica officinalis > Centella asiatica > Withania somnifera > Terminalia bellerica > Glycyrrhiza glabra > Evolvulus alsinoides > Zingiber officinale > Andrographis paniculata şeklinde sıralanmıştır. Lipit peraksidasyon denemesinde Emblica officinalis ve Evolvulus alsinoides en yüksek etkiyi göstermiştir. İnhibisyon değerleri 100 μg/ml konsantrasyonda 39,14 ± 2,1% ve 36,38 ± 1,3% şeklinde hesaplanmıştır (P < 0,05). Bu çalışma ile denenen bütün bitkilerin orta derecede antioksidant aktiviteye sahip olduğu gözlenmiştir.

Anahtar Kelime: metanol tıbbi bitkiler bitki özütü lipit peroksidasyonu antioksidanlar

Konular: Biyoloji

Bazı tıbbi bitkilerin antioksidan aktiviteleri

Öz:

The antioxidant properties of the methanol extracts of 10 medicinal plants were evaluated with the DPPH (1,1-diphenyl- 2-picryl hydrazyl) test, hydroxyl scavenging test, and lipid peroxidation assay. The methanol extract of Emblica officinalis was the most active according to the DPPH test, with an IC50 value of 7.92 ± 0.1 μg/ml, followed by Asparagus racemosus, with an IC50 value of 9.28 ± 0.2 μg/ml. The minimum free radical scavenging activity was shown by Zingiber officinale, with an IC50 value of 44.48 ± 1.8 μg/ml. The hydroxyl radical scavenging activity of the methanolic extracts of various plants was as follows: Asparagus racemosus > Terminalia chebula > Emblica officinalis > Centella asiatica > Withania somnifera > Terminalia bellerica > Glycyrrhiza glabra > Evolvulus alsinoides > Zingiber officinale > Andrographis paniculata. According to the lipid peroxidation assay the extracts of Emblica officinalis and Evolvulus alsinoides showed the greatest effectiveness, with inhibition values of 39.14 ± 2.1% and 36.38 ± 1.3%, respectively, at the 100-μg/m concentration (P < 0.05). Results of the present study suggest that all the tested plant materials had moderate to potent antioxidant activity.

Anahtar Kelime: lipid peroxidation antioxidants methanol medicinal plants plant extracts

Konular: Biyoloji

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	JAIN P, RAVICHANDRAN V, SHARMA S, AGRAWAL R (2008). The antioxidant activity of some medicinal plants. , 197 - 202.
Chicago	JAIN Prateek Kumar,RAVICHANDRAN Veerasamy,SHARMA Simant,AGRAWAL Ram K. The antioxidant activity of some medicinal plants. (2008): 197 - 202.
MLA	JAIN Prateek Kumar,RAVICHANDRAN Veerasamy,SHARMA Simant,AGRAWAL Ram K. The antioxidant activity of some medicinal plants. , 2008, ss.197 - 202.
AMA	JAIN P,RAVICHANDRAN V,SHARMA S,AGRAWAL R The antioxidant activity of some medicinal plants. . 2008; 197 - 202.
Vancouver	JAIN P,RAVICHANDRAN V,SHARMA S,AGRAWAL R The antioxidant activity of some medicinal plants. . 2008; 197 - 202.
IEEE	JAIN P,RAVICHANDRAN V,SHARMA S,AGRAWAL R "The antioxidant activity of some medicinal plants." , ss.197 - 202, 2008.
ISNAD	JAIN, Prateek Kumar vd. "The antioxidant activity of some medicinal plants". (2008), 197-202.

APA	JAIN P, RAVICHANDRAN V, SHARMA S, AGRAWAL R (2008). The antioxidant activity of some medicinal plants. Turkish Journal of Biology, 32(3), 197 - 202.
Chicago	JAIN Prateek Kumar,RAVICHANDRAN Veerasamy,SHARMA Simant,AGRAWAL Ram K. The antioxidant activity of some medicinal plants. Turkish Journal of Biology 32, no.3 (2008): 197 - 202.
MLA	JAIN Prateek Kumar,RAVICHANDRAN Veerasamy,SHARMA Simant,AGRAWAL Ram K. The antioxidant activity of some medicinal plants. Turkish Journal of Biology, vol.32, no.3, 2008, ss.197 - 202.
AMA	JAIN P,RAVICHANDRAN V,SHARMA S,AGRAWAL R The antioxidant activity of some medicinal plants. Turkish Journal of Biology. 2008; 32(3): 197 - 202.
Vancouver	JAIN P,RAVICHANDRAN V,SHARMA S,AGRAWAL R The antioxidant activity of some medicinal plants. Turkish Journal of Biology. 2008; 32(3): 197 - 202.
IEEE	JAIN P,RAVICHANDRAN V,SHARMA S,AGRAWAL R "The antioxidant activity of some medicinal plants." Turkish Journal of Biology, 32, ss.197 - 202, 2008.
ISNAD	JAIN, Prateek Kumar vd. "The antioxidant activity of some medicinal plants". Turkish Journal of Biology 32/3 (2008), 197-202.