Total antioxidant capacity: a biomarker in biomedical and nutritional studies

Carlos KUSANO, (Adventist Univercity Center of Sao Paulo)
Bucalen FERRARİ (Univercity Paranaense Brazil)
Journal of Cell and Molecular Biology
91 8
Yıl: 2008 Cilt: 7 Sayı: 1 Sayfa Aralığı: 1 - 15 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Total antioxidant capacity: a biomarker in biomedical and nutritional studies

Öz:
Antioksidan savunmalar zayıfladığında vücut hücreleri ve dokuları disfonksiyon ve/veya hastalık geliştirmeye daha yatkın hale gelirler. Böylece, yeterli antioksidan düzeylerinin doz aşılmadan sürdürülmesi, çok sayıda hastalık durumunu önlemek ve hatta control altına almak için gereklidir. Bu derleme makale biyokimyada, tıpta, gıda ve beslenme bilimlerinde bir hastalık biyomarkörü olarak TAC, total antioksidan kapasite testi, kullanımını anlatmakta ve ve tartışmaktadır. Birçok farklı patofizyolojik durumda (kalp hastalıkları ve vasküler hastalıklar, diyabet, nörolojik ve psikiyatrik hastalıklar, renal hastalıklar ve akciğer hastalıkları) kullanımı için çeşitli uyarıların dikkatlice yapılmasının gerekliliğine rağmen (uygun metodun seçilmesi, hücresel antioksidanlar gibi diğer antioksidanların kullanımı, genetik antioksidan cevap elementleri (ARE) veya antioksidan vitaminler ve değerli oksidatif/nitrozatif biyomarkörlerin kullanımı) TAC teşhis ve prognozda kullanılacak güvenilir bir biyomarkör olabilir. TAC, hastalık risklerinin ve hastalıkların önlenmesi için anti yaşlanma stratejileri de dahil olmak üzere, TAC açısından zengin yiyeceklerle besinsel müdahaleler gerçekleştirmek üzere kullanılabilir.
Anahtar Kelime: genel bakış solunum yolu hastalıkları nöroloji böbrek hastalıkları kalp damar sistemi fizyoloji yaşlanma antioksidanlar diyabet

Konular: Biyokimya ve Moleküler Biyoloji

Total antioksidan kapasitesi: biyomedikal ve besinsel çalışmalarda bir biyomarkör

Öz:
When antioxidant defenses are weakened, body cells and tissues become more prone to develop dysfunction and/or disease. Then, the maintenance of adequate antioxidant levels, but not overdosage, is essential to prevent or even manage a great number of disease conditions. This review strongly describes and discusses the use of TAC, total antioxidant capacity test, as a biomarker of disease in biochemistry, medicine, food and nutritional sciences. In many different pathophysiological conditions (heart and vascular diseases, diabetes mellitus, neurological and psychiatric disorders, renal disorders and lung diseases), TAC could be a reliable biomarker of diagnostics and prognostics, although several cautions for its use should be carefully done (choice of apropriate method, use of other antioxidant biomarkers such as cell antioxidants, genetic antioxidant-response elements (ARE) or antioxidant vitamins, and use of valuable oxidative/nitrosative biomarkers). TAC could be useful to evaluate nutritional interventions with TAC-rich foods on disease risk and prevention, including anti-aging strategies.
Anahtar Kelime: kidney diseases cardiovascular system physiology aging antioxidants diabetes reviews respiratory diseases neurology

Konular: Biyokimya ve Moleküler Biyoloji
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
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APA KUSANO C, FERRARİ B (2008). Total antioxidant capacity: a biomarker in biomedical and nutritional studies. , 1 - 15.
Chicago KUSANO Carlos,FERRARİ Bucalen Total antioxidant capacity: a biomarker in biomedical and nutritional studies. (2008): 1 - 15.
MLA KUSANO Carlos,FERRARİ Bucalen Total antioxidant capacity: a biomarker in biomedical and nutritional studies. , 2008, ss.1 - 15.
AMA KUSANO C,FERRARİ B Total antioxidant capacity: a biomarker in biomedical and nutritional studies. . 2008; 1 - 15.
Vancouver KUSANO C,FERRARİ B Total antioxidant capacity: a biomarker in biomedical and nutritional studies. . 2008; 1 - 15.
IEEE KUSANO C,FERRARİ B "Total antioxidant capacity: a biomarker in biomedical and nutritional studies." , ss.1 - 15, 2008.
ISNAD KUSANO, Carlos - FERRARİ, Bucalen. "Total antioxidant capacity: a biomarker in biomedical and nutritional studies". (2008), 1-15.
APA KUSANO C, FERRARİ B (2008). Total antioxidant capacity: a biomarker in biomedical and nutritional studies. Journal of Cell and Molecular Biology, 7(1), 1 - 15.
Chicago KUSANO Carlos,FERRARİ Bucalen Total antioxidant capacity: a biomarker in biomedical and nutritional studies. Journal of Cell and Molecular Biology 7, no.1 (2008): 1 - 15.
MLA KUSANO Carlos,FERRARİ Bucalen Total antioxidant capacity: a biomarker in biomedical and nutritional studies. Journal of Cell and Molecular Biology, vol.7, no.1, 2008, ss.1 - 15.
AMA KUSANO C,FERRARİ B Total antioxidant capacity: a biomarker in biomedical and nutritional studies. Journal of Cell and Molecular Biology. 2008; 7(1): 1 - 15.
Vancouver KUSANO C,FERRARİ B Total antioxidant capacity: a biomarker in biomedical and nutritional studies. Journal of Cell and Molecular Biology. 2008; 7(1): 1 - 15.
IEEE KUSANO C,FERRARİ B "Total antioxidant capacity: a biomarker in biomedical and nutritional studies." Journal of Cell and Molecular Biology, 7, ss.1 - 15, 2008.
ISNAD KUSANO, Carlos - FERRARİ, Bucalen. "Total antioxidant capacity: a biomarker in biomedical and nutritional studies". Journal of Cell and Molecular Biology 7/1 (2008), 1-15.
Sayfa Oluşturulma Tarihi
16-04-2024 20:31

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