Alterations in bones of prepubertal rats with testicular torsion

tander, berna; CANTÜRK, Ferhan; TANDER, Burak; YILDIZ, Levent; BIÇAKÇI, Ünal; BAŞOĞLU, Tarık

Alterations in bones of prepubertal rats with testicular torsion

Berna TANDER, (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Samsun, Türkiye)

Ünal BIÇAKÇI, (Gaziosmanpaşa Üniversitesi, Tıp Fakültesi, Pediatrik Cerrahi Anabilim Dalı, Tokat, Türkiye)

Burak TANDER, (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Pediatrik Cerrahi Bilim Dalı, Samsun, Türkiye)

Tarık BAŞOĞLU, (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Nükleer Tıp Anabilim Dalı, Samsun, Türkiye)

Levent YILDIZ, (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Patoloji Anabilim Dalı, Samsun, Türkiye)

Ferhan CANTÜRK (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Samsun, Türkiye)

Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi

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Yıl: 2008 Cilt: 54 Sayı: 1 Sayfa Aralığı: 1 - 3 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Alterations in bones of prepubertal rats with testicular torsion

Öz:

Amaç: Testiküler torsiyon çocuklarda hipogonadizmin nedenlerinden birisidir. Bu çalışmada, prepubertal testis torsiyonunun erişkinlikte kemikler üzerindeki etkisini dansitometre ve histopatolojik yöntemleri kullanarak değerlendirmeyi amaçladık. Gereç ve Yöntem: Otuz-iki prepubertal erkek Wistar albino rat randomize olarak dört eşit gruba ayrıldı. SHAM grubuna yalnızca skrotal insizyon uygulandı. Torsiyon grubunda her iki testis saat yönünde 720° torsiyone edildi. Torsiyon/detorsiyon grubunda testisler torsiyondan dört gün sonra detorsiyone edildi. Torsiyon/orşiektomi grubunda bilateral torsiyondan dört gün sonra orşiektomi uygulandı. Cerrahiden üç ay sonra, kemik mineral yoğunluğu (KMY) ve kemik mineral içeriği (KMİ) DXA ile, kemik korteks kalınlığı (KKK) da histopatolojik olarak değerlendirildi.Bulgular: En düşük KMY ve KMİ değerleri torsiyon grubunda (ortalama 0,075 g/cm2 and 0,290 g), en yüksek ise SHAM grubunda (ortalama 0,142 g/cm2 and 0,488 g) bulundu. KKK, SHAM grubunda ortalama 388,52 mm, torsiyon grubunda ise ortalama 220,16 mm bulundu (p<0,05).Sonuç: Prepubertal ratlarda bilateral testiküler torsiyon, erişkin dönemde kemik kaybına yol açabilir. Ratlarda tedavide detorsiyon uygulanması, torsiyonun kemik üzerindeki olumsuz etkilerini azaltabilir. Türk Fiz Tıp Rehab Derg 2008;54:1-3.

Anahtar Kelime: Sıçanlar Kemik yoğunluğu Spermatik kord torsiyonu Densitometri Modeller, hayvan Sıçan, Wistar Histopatoloji Osteoporoz

Konular: Rehabilitasyon

Testiküler torsiyonlu prepubertal ratlarda kemik değişimleri

Öz:

Objective: Testicular torsion is one of the leading causes of hypogonadism among children. We aimed to evaluate the effects of testicular torsion in prepubertal rats using densitometry and a histopathological study in adulthood. Materials and Methods: Thirty-two prepubertal male Wistar albino rats were randomly divided into four equal groups. The rats in the SHAM group underwent scrotal incision only. In the torsion group rats, both testes were torsioned 720° in a clockwise direction. In the torsion/detorsion group, the testes were detorsioned after four days of torsion. The torsion/orchidectomy rats underwent orchidectomy on the fourth day subsequent to bilateral torsion. Three months after surgery, bone mineral density (BMD) and content (BMC) were measured by DXA and bone cortex thickness (BCT) measurements were performed histopathologically. Results: The lowest values of BMD and BMC were in rats with torsion (mean 0.075 g/cm2 and 0.290 g), and highest in the SHAM group (mean 0.142 g/cm2 and 0.488 g). The SHAM group had a mean of 388.52 mm BCT, whereas the torsion group had a mean of only 220.16 mm (p<0.05).Conclusion: Bilateral testicular torsion in prepubertal rats may lead to bone loss in adulthood. Detorsion may prevent the negative effects of torsion on bones in rats. Turk J Phys Med Rehab 2008;54:1-3.

Anahtar Kelime: Densitometry Models, Animal Rats, Wistar Histopathology Osteoporosis Rats Bone Density Spermatic Cord Torsion

Konular: Rehabilitasyon

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	tander b, BIÇAKÇI Ü, TANDER B, BAŞOĞLU T, YILDIZ L, CANTÜRK F (2008). Alterations in bones of prepubertal rats with testicular torsion. , 1 - 3.
Chicago	tander berna,BIÇAKÇI Ünal,TANDER Burak,BAŞOĞLU Tarık,YILDIZ Levent,CANTÜRK Ferhan Alterations in bones of prepubertal rats with testicular torsion. (2008): 1 - 3.
MLA	tander berna,BIÇAKÇI Ünal,TANDER Burak,BAŞOĞLU Tarık,YILDIZ Levent,CANTÜRK Ferhan Alterations in bones of prepubertal rats with testicular torsion. , 2008, ss.1 - 3.
AMA	tander b,BIÇAKÇI Ü,TANDER B,BAŞOĞLU T,YILDIZ L,CANTÜRK F Alterations in bones of prepubertal rats with testicular torsion. . 2008; 1 - 3.
Vancouver	tander b,BIÇAKÇI Ü,TANDER B,BAŞOĞLU T,YILDIZ L,CANTÜRK F Alterations in bones of prepubertal rats with testicular torsion. . 2008; 1 - 3.
IEEE	tander b,BIÇAKÇI Ü,TANDER B,BAŞOĞLU T,YILDIZ L,CANTÜRK F "Alterations in bones of prepubertal rats with testicular torsion." , ss.1 - 3, 2008.
ISNAD	tander, berna vd. "Alterations in bones of prepubertal rats with testicular torsion". (2008), 1-3.

APA	tander b, BIÇAKÇI Ü, TANDER B, BAŞOĞLU T, YILDIZ L, CANTÜRK F (2008). Alterations in bones of prepubertal rats with testicular torsion. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, 54(1), 1 - 3.
Chicago	tander berna,BIÇAKÇI Ünal,TANDER Burak,BAŞOĞLU Tarık,YILDIZ Levent,CANTÜRK Ferhan Alterations in bones of prepubertal rats with testicular torsion. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi 54, no.1 (2008): 1 - 3.
MLA	tander berna,BIÇAKÇI Ünal,TANDER Burak,BAŞOĞLU Tarık,YILDIZ Levent,CANTÜRK Ferhan Alterations in bones of prepubertal rats with testicular torsion. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, vol.54, no.1, 2008, ss.1 - 3.
AMA	tander b,BIÇAKÇI Ü,TANDER B,BAŞOĞLU T,YILDIZ L,CANTÜRK F Alterations in bones of prepubertal rats with testicular torsion. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi. 2008; 54(1): 1 - 3.
Vancouver	tander b,BIÇAKÇI Ü,TANDER B,BAŞOĞLU T,YILDIZ L,CANTÜRK F Alterations in bones of prepubertal rats with testicular torsion. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi. 2008; 54(1): 1 - 3.
IEEE	tander b,BIÇAKÇI Ü,TANDER B,BAŞOĞLU T,YILDIZ L,CANTÜRK F "Alterations in bones of prepubertal rats with testicular torsion." Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, 54, ss.1 - 3, 2008.
ISNAD	tander, berna vd. "Alterations in bones of prepubertal rats with testicular torsion". Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi 54/1 (2008), 1-3.