Yıl: 2008 Cilt: 54 Sayı: 2 Sayfa Aralığı: 79 - 81 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis

Öz:
Metotreksat (MTX), Romatoid Artrit (RA) tedavisinde yaygın olarak kullanılan bir antiromatizmal ilaçtır. Düşük doz MTX tedavisine bağlı pansitopeni yaşamı tehdit eden istenmeyen bir etkidir, bu da bilinen risk faktörleriyle birlikte görülebilir. Bu olgu sunumunda pansitopeni nedeniyle kliniğimize yönlendirilen 33 yaşında 6 yıldır düşük doz MTX kullanan RA’lı kadın hasta bildirilmiştir. Bu olguyla, düşük doz MTX tedavisinin güvenli olduğunu fakat diğer ilaçlarla birlikte verildiğinde ve dehidratasyon hallerinde dikkatli olunması gerektiğini vurgulamak istedik.
Anahtar Kelime: Erişkin Methotreksat Pansitopeni Kadın İlaç etkileşimleri Artrit, romatoid

Konular: Rehabilitasyon

Düşük doz metotreksat alan romatoid artritli bir hastada pansitopeni gelişimi

Öz:
Methotrexate (MTX) is one of the most widely used anti-rheumatoid drugs for Rheumatoid Arthritis (RA). Pancytopenia associated with low dose MTX therapy is a life threatening adverse effect often associated with known risk factors. In this article a 33-year-old woman taking low dose MTX for 6 years for RA referred to our clinic with pancytopenia is presented. This case highlights that low dose MTX is safe but the patient should be evaluated for dehydration, medication interactions and renal function.
Anahtar Kelime: Female Drug Interactions Arthritis, Rheumatoid Adult Methotrexate Pancytopenia

Konular: Rehabilitasyon
Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
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APA Güler N, tander b, Kisacik B, UTKU U, ÇEVİK A, ERÇOLAK V, CENGİZ ECEMİŞ G, ECEMİŞ Ö, ASLAN R, CANTÜRK F (2008). Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis. , 79 - 81.
Chicago Güler Nil,tander berna,Kisacik Bunyamin,UTKU Umut,ÇEVİK Ata,ERÇOLAK VEHBİ,CENGİZ ECEMİŞ GÜLÇİN,ECEMİŞ Özgür,ASLAN Rahmi,CANTÜRK Ferhan Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis. (2008): 79 - 81.
MLA Güler Nil,tander berna,Kisacik Bunyamin,UTKU Umut,ÇEVİK Ata,ERÇOLAK VEHBİ,CENGİZ ECEMİŞ GÜLÇİN,ECEMİŞ Özgür,ASLAN Rahmi,CANTÜRK Ferhan Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis. , 2008, ss.79 - 81.
AMA Güler N,tander b,Kisacik B,UTKU U,ÇEVİK A,ERÇOLAK V,CENGİZ ECEMİŞ G,ECEMİŞ Ö,ASLAN R,CANTÜRK F Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis. . 2008; 79 - 81.
Vancouver Güler N,tander b,Kisacik B,UTKU U,ÇEVİK A,ERÇOLAK V,CENGİZ ECEMİŞ G,ECEMİŞ Ö,ASLAN R,CANTÜRK F Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis. . 2008; 79 - 81.
IEEE Güler N,tander b,Kisacik B,UTKU U,ÇEVİK A,ERÇOLAK V,CENGİZ ECEMİŞ G,ECEMİŞ Ö,ASLAN R,CANTÜRK F "Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis." , ss.79 - 81, 2008.
ISNAD Güler, Nil vd. "Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis". (2008), 79-81.
APA Güler N, tander b, Kisacik B, UTKU U, ÇEVİK A, ERÇOLAK V, CENGİZ ECEMİŞ G, ECEMİŞ Ö, ASLAN R, CANTÜRK F (2008). Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, 54(2), 79 - 81.
Chicago Güler Nil,tander berna,Kisacik Bunyamin,UTKU Umut,ÇEVİK Ata,ERÇOLAK VEHBİ,CENGİZ ECEMİŞ GÜLÇİN,ECEMİŞ Özgür,ASLAN Rahmi,CANTÜRK Ferhan Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi 54, no.2 (2008): 79 - 81.
MLA Güler Nil,tander berna,Kisacik Bunyamin,UTKU Umut,ÇEVİK Ata,ERÇOLAK VEHBİ,CENGİZ ECEMİŞ GÜLÇİN,ECEMİŞ Özgür,ASLAN Rahmi,CANTÜRK Ferhan Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, vol.54, no.2, 2008, ss.79 - 81.
AMA Güler N,tander b,Kisacik B,UTKU U,ÇEVİK A,ERÇOLAK V,CENGİZ ECEMİŞ G,ECEMİŞ Ö,ASLAN R,CANTÜRK F Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi. 2008; 54(2): 79 - 81.
Vancouver Güler N,tander b,Kisacik B,UTKU U,ÇEVİK A,ERÇOLAK V,CENGİZ ECEMİŞ G,ECEMİŞ Ö,ASLAN R,CANTÜRK F Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi. 2008; 54(2): 79 - 81.
IEEE Güler N,tander b,Kisacik B,UTKU U,ÇEVİK A,ERÇOLAK V,CENGİZ ECEMİŞ G,ECEMİŞ Ö,ASLAN R,CANTÜRK F "Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis." Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, 54, ss.79 - 81, 2008.
ISNAD Güler, Nil vd. "Low dose methotrexate associated pancytopenia in a patient with rheumatoid arthritis". Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi 54/2 (2008), 79-81.