Yıl: 2008 Cilt: 2 Sayı: 4 Sayfa Aralığı: 93 - 98 Metin Dili: Türkçe

Spitz Nevüs’ün klinik, dermatoskopik ve histopatolojik özellikleri

Öz:
Amaç: Spitz nevüs, çocuklarda daha sık görülen benin, çoğunlukla edinsel bir melanositik nevüstür. Bu çalışmanın amacı Spitz nevüs tanısı alan hastaların klinik, dermatoskopik ve histopatolojik özelliklerini tanımlamaktır. Yöntem: İki bin-2005 yılları arasında histopatolojik ve klinik olarak Spitz nevüs tanısı alan hastaların verileri, dermatoskopik görüntüleri ve biyopsi preparatları geriye dönük olarak incelendi. İstatistiksel analiz için tanımlayıcı testler ve ki-kare testi kullanıldı. Bulgular: Çalışmaya dahil edilen 30 hastanın %56.7’si kadındı. Hastaların yaş ortancası 15.5 yıl olup (Aralık: 3-49 yıl), %40’ı 12 yaşın altındaydı. Biyopsi öncesi kaydedilen en sık ön tanılar Spitz nevüs (%33) ve melanositik nevüstü (%30). Hastalık süresinin ortancası 12 ay (Aralık:1ay-20 yıl) idi. Lezyonların ortanca çapı 5 mm idi. Hem erişkin hem de çocukluk döneminde lezyonlar en sık olarak alt ekstremitede (%44.8) yerleşim göstermekteydi ve alt ekstremite yerleşimi kadınlarda daha sıktı (p=0.007). En sık saptanan histopatolojik tipler Spitz nevüs %53.5 (n=15) ve Reed nevüstü %32 (n=9). Dermatoskopi yapılmış olan 16 pigmente lezyonun %31.3’ünde retiküler, %18.8’inde patlayan yıldız, %18.8’inde ise atipik patern gözlendi. Tartışma ve Sonuç: Spitz nevüs hem çocuklarda hem de erişkinlerde görülmektedir. Melanositik nevüse benzerlik gösteren pigmente tipi en sık formudur ve alt ekstremite yerleşimi kadınlarda daha sıktır.
Anahtar Kelime: Ben Dermoskopi Nevüs, epiteloid ve iğ hücreli Geriyedönük çalışma Histopatoloji

Clinical, dermatoscopic, and histopathological features of spitz nevus

Öz:
Aim: Spitz nevus is a benign, mostly acquired melanocytic nevus, which is commonly seen in childhood. The aim of this study was to describe the clinical, dermatoscopic, and histopathological features of Spitz nevus. Methods: Clinical data, histopathological slides, and dermatoscopic images of the patients that were histopathologically or clinically diagnosed with Spitz nevus between 2000-2005 were retrospectively analyzed. For statistical analysis, descriptive statistics and chi-square tests were used. Results: Among the 30 patients included in the study, 56.7% were female. Median patient age was 15.5 years (range: 3-49 years) and 40% were younger than 12 years of age. The most frequent clinical diagnoses before biopsy were Spitz nevus (33%) and melanocytic nevus (30%). Median disease duration was 12 months (range: 1month-20 years) and mean diameter of the lesions was 5 mm. Lesions were most commonly localized on the lower extremities (44.8%) in both children and adults, and lower extremity localization was more common in females (P=0.007). The most common histopathological types noted were Spitz nevus 53.5% (n=15) and Reed nevus 32% (n=9). Dermatoscopy was performed in 16 patients; 31.3% had reticular pattern, 18.8% had starburst pattern, and 18.8% had atypical pattern. Conclusion: Spitz nevi were seen in both children and adults. Pigmented Spitz nevus, which resembles melanocytic nevus, was the most common type and lower extremity localization was more common in females.
Anahtar Kelime: Nevus Nevus, Epithelioid and Spindle Cell Dermoscopy Retrospective Studies Histopathology

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA EVANS S, GÜNDÜZ Ö, ERKİN G, BOZTEPE G, ŞAHİN S, ÖZKAYA Ö (2008). Spitz Nevüs’ün klinik, dermatoskopik ve histopatolojik özellikleri. Türk Dermatoloji Dergisi, 2(4), 93 - 98.
Chicago EVANS Sibel Ersoy,GÜNDÜZ Özge,ERKİN Gül,BOZTEPE Gonca,ŞAHİN Sedef,ÖZKAYA Özay Spitz Nevüs’ün klinik, dermatoskopik ve histopatolojik özellikleri. Türk Dermatoloji Dergisi 2, no.4 (2008): 93 - 98.
MLA EVANS Sibel Ersoy,GÜNDÜZ Özge,ERKİN Gül,BOZTEPE Gonca,ŞAHİN Sedef,ÖZKAYA Özay Spitz Nevüs’ün klinik, dermatoskopik ve histopatolojik özellikleri. Türk Dermatoloji Dergisi, vol.2, no.4, 2008, ss.93 - 98.
AMA EVANS S,GÜNDÜZ Ö,ERKİN G,BOZTEPE G,ŞAHİN S,ÖZKAYA Ö Spitz Nevüs’ün klinik, dermatoskopik ve histopatolojik özellikleri. Türk Dermatoloji Dergisi. 2008; 2(4): 93 - 98.
Vancouver EVANS S,GÜNDÜZ Ö,ERKİN G,BOZTEPE G,ŞAHİN S,ÖZKAYA Ö Spitz Nevüs’ün klinik, dermatoskopik ve histopatolojik özellikleri. Türk Dermatoloji Dergisi. 2008; 2(4): 93 - 98.
IEEE EVANS S,GÜNDÜZ Ö,ERKİN G,BOZTEPE G,ŞAHİN S,ÖZKAYA Ö "Spitz Nevüs’ün klinik, dermatoskopik ve histopatolojik özellikleri." Türk Dermatoloji Dergisi, 2, ss.93 - 98, 2008.
ISNAD EVANS, Sibel Ersoy vd. "Spitz Nevüs’ün klinik, dermatoskopik ve histopatolojik özellikleri". Türk Dermatoloji Dergisi 2/4 (2008), 93-98.