The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model

GÖL, Kamil; ELMALI, Muzaffer; BAHÇIVAN, Muzaffer; KOLBAKIR, FERŞAT

The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model

Muzaffer BAHÇIVAN, (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Kardiyovasküler Cerrahi Anabilim Dalı, Samsun, Türkiye)

Muzaffer ELMALI, (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Radyoloji Anabilim Dalı, Samsun, Türkiye)

FERŞAT KOLBAKIR, (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Kardiyovasküler Cerrahi Anabilim Dalı, Samsun, Türkiye)

Kamil GÖL (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Kardiyovasküler Cerrahi Anabilim Dalı, Samsun, Türkiye)

Anadolu Kardiyoloji Dergisi

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Yıl: 2009 Cilt: 9 Sayı: 2 Sayfa Aralığı: 123 - 127 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model

Öz:

Amaç: Yarışmalı akım, kısmen tıkalı olan nativ arterdeki akımın greftteki akımla distal perfüzyon için yarışması olarak tanımlanır. Bu çalışmanın amacı karotis arterde değişik oranlarda darlık oluşturulan tavşan modelinde venöz greftlerde velosite ve volum miktarını ölçerek yarışmalı akımın etkisini araştırmaktır.Yöntemler: Bu deneysel prospektif çalışmada 33 tavşan üç gruba ayrıldı. Grup 1’de kommon karotis arter total olarak bağlandı. Grup 2’de karotis arter %50 darlık meydana gelecek şekilde daraltılırken Grup 3’te arter tamamen açık bırakıldı.Juguler ven çevrilerek “end-to-side” teknikle kommon karotis arterin distal ve proksimaline anastomoz edildi. Hemodinamik değerlendirme amacıyla, cerrahi girişimden önce ve 2 ay sonra karotis arterlerde ortalama kan basıncı, total akım hacmi ve akım hızı ölçümleri Doppler ultrasonografi ile yapıldı. İstatistiksel analizde gruplardaki veriler Ki-kare ve Kruskal Wallis varyans analiz testleri ile değerlendirildi.Bulgular: Venöz greftlerdeki ortalama akım hızı (Grup 1 - 16.8±6.7 cm/sn, Grup 2 - 14.1±6.1 cm/sn ve Grup 3 - 12.1±6.7 cm/sn) ve akım volümü (Grup 1 - 33.9±11.5 mL/dk, Grup 2 - 29.0±8.3 mL/dk, Grup 3 - 24.4±12.8 mL/dk) istatistiksel olarak grup 1, 2 ve 3 arasında farklı değildi (p>0.05). Sonuç: Oluşturulan tavşan modelinde, darlık oranlarının az olduğu karotis arterlere uygulanan venöz baypas greftlerinde, volüm ve hız azalması istatistiksel olarak anlamlı tespit edilmedi. Her ne kadar kısa dönemde gruplar arasında kompetitif akımın etkisi anlamlı bulunmasa da uzun dönemde önemli olabilir.

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Baypas modelinde yarışmalı akımın venöz greftlerdeki akım ve velosite üzerine etkisi

Öz:

Objective: The term “competitive flow” defines the flow from a partially stenosed native artery that “competes” with the flow from a graft to perfuse the distal tissues. The purpose of our study is to investigate the effects of competitive flow at different degrees of stenosis at common carotid artery, in a rabbit model by measuring both the flow volume and velocity in the venous graft. Methods: This prospective experimental study included 33 rabbits, which were divided into three groups: in Group 1, the common carotid arteries were ligated to form a total occlusion, in Group 2, the common carotid arteries were externally incompletely ligated to achieve 50% stenosis, and in Group 3, common carotid arteries were fully patent. The jugular vein was reversed and anastomosed to proximal and distal common carotid arteries using end to side anastomosis technique. Mean arterial pressure, the total flow and velocity were measured in native carotid arteries prior to surgery and in venous grafts 2 months after surgery using Doppler ultrasonography. Statistical analysis was performed using Chi-square test and Kruskal Wallis analysis of variances.Results: There were no differences in graft mean velocity (Group 1 - 16.8±6.7 cm/sec, Group 2 - 14.1±6.1 cm/sec and Group 3 - 12.1±6.7 cm/sec), and mean flow volume (Group 1 - 33.9±11.5 mL/min, Group 2 - 29.0±8.3 mL/min, and Group 3 - 24.4±12.8 mL/min) between groups after surgery (p>0.05 for both). Conclusion: As it was the case in this rabbit model, the reduction of flow volume or velocity in lesser degrees of stenosis in the carotid artery venous bypass grafts is not significant in a statistical perspective.Although in short-term this effect did not create a difference for graft patencies between the groups, it may be important in long-term

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	BAHÇIVAN M, ELMALI M, KOLBAKIR F, GÖL K (2009). The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model. , 123 - 127.
Chicago	BAHÇIVAN Muzaffer,ELMALI Muzaffer,KOLBAKIR FERŞAT,GÖL Kamil The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model. (2009): 123 - 127.
MLA	BAHÇIVAN Muzaffer,ELMALI Muzaffer,KOLBAKIR FERŞAT,GÖL Kamil The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model. , 2009, ss.123 - 127.
AMA	BAHÇIVAN M,ELMALI M,KOLBAKIR F,GÖL K The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model. . 2009; 123 - 127.
Vancouver	BAHÇIVAN M,ELMALI M,KOLBAKIR F,GÖL K The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model. . 2009; 123 - 127.
IEEE	BAHÇIVAN M,ELMALI M,KOLBAKIR F,GÖL K "The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model." , ss.123 - 127, 2009.
ISNAD	BAHÇIVAN, Muzaffer vd. "The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model". (2009), 123-127.

APA	BAHÇIVAN M, ELMALI M, KOLBAKIR F, GÖL K (2009). The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model. Anadolu Kardiyoloji Dergisi, 9(2), 123 - 127.
Chicago	BAHÇIVAN Muzaffer,ELMALI Muzaffer,KOLBAKIR FERŞAT,GÖL Kamil The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model. Anadolu Kardiyoloji Dergisi 9, no.2 (2009): 123 - 127.
MLA	BAHÇIVAN Muzaffer,ELMALI Muzaffer,KOLBAKIR FERŞAT,GÖL Kamil The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model. Anadolu Kardiyoloji Dergisi, vol.9, no.2, 2009, ss.123 - 127.
AMA	BAHÇIVAN M,ELMALI M,KOLBAKIR F,GÖL K The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model. Anadolu Kardiyoloji Dergisi. 2009; 9(2): 123 - 127.
Vancouver	BAHÇIVAN M,ELMALI M,KOLBAKIR F,GÖL K The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model. Anadolu Kardiyoloji Dergisi. 2009; 9(2): 123 - 127.
IEEE	BAHÇIVAN M,ELMALI M,KOLBAKIR F,GÖL K "The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model." Anadolu Kardiyoloji Dergisi, 9, ss.123 - 127, 2009.
ISNAD	BAHÇIVAN, Muzaffer vd. "The effect of competitive flow on both the flow and the velocity in venous grafts in a bypass model". Anadolu Kardiyoloji Dergisi 9/2 (2009), 123-127.