Aetiology of deep vein thrombosis in 63 Turkish patients

ÇEBİ, Niyazi; TANRIVERDİ, Süleyman

Aetiology of deep vein thrombosis in 63 Turkish patients

Niyazi ÇEBİ, (İstanbul Özel Medicine Hospital, Kalp Damar Cerrahisi Kliniği, İstanbul, Türkiye)

Süleyman TANRIVERDİ (Institute für Herz Kreilaufforschung, Univercity Witten Herdecke, Dortmund, Germany)

Turkish Journal of Medical Sciences

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Yıl: 2009 Cilt: 39 Sayı: 2 Sayfa Aralığı: 223 - 227 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Aetiology of deep vein thrombosis in 63 Turkish patients

Öz:

Amaç: Derin ven trombozunun etiyolojisi dünya popülasyonları arasında farklılıklar göstermektedir. Bu çalışmada derin ven trombozlu Türk hastalarındaki derin ven trombozunun etiyolojisi araştırılmaktadır. Yöntem ve Gereç: Kasım 2006 ve Aralık 2007 tarihleri arsında derin ven trombozlu 63 hasta polikliniğimizde tedavi ve takip edilmiştir. Yaş ortalamaları 49,35 + 14,19 yıl (25 – 85 yıl) olan 29 kadın ve 34 erkek hasta tedavi edilmiştir. Derin ven trombozu tanısı doppler ve duplex sonografiyle konmuştur. Minor pulmoner enfarktüs 5 hastada mevcuttu. Bulgular: 58 hasta (% 92,06) takiplere katıldı. Derin ven trombozunun nedeni anemnez ve fiziksel muayeneye göre 43 hastada (% 68,25) tesbit edilmiştir. Immobilizasyon 33 hastada mevcuttu (% 52,38). Trombofili testi toplam 29 hastada uygulanabildi. Hayatında ilk defa derin ven trombozu geçiren 20 hastanın (% 31,74) anemnezine göre derin ven trombozu için herhangi bilinen bir risk faktörü yoktu. Bunlardan 12 hastada (% 60) trombofili testi Protein C, Protein S, APCR (Activated Protein C Rezistansı) ve Factor V Leiden analizleriyle yapıldı. Trombofili 12 hastanın 11 inde (% 91,66) pozitif bulunmuştur. Sonuç: Türk populasyonundaki derin ven trombozunun ana etiolojik faktorleri immobilizasyon (% 52,38) ve thrombofilidir (% 51,72). Her iki nedenin sıklığı ortalama olarak eşittir. Hayatında ilk defa derin ven trombozu gelişen genç sağlıklı Türk populasyonunda trombofili bu hastaların % 91,66’ ında pozitif olabilir.

Anahtar Kelime: Etiyoloji Trombofili Venöz tromboz İzleme çalışmaları Ultrasonografi, doppler, renkli

Konular: Cerrahi

Altmış üç derin ven trombozlu hastada etiyoloji

Öz:

Aim: The aetiology of deep vein thrombosis differs among populations throughout the world. This study examines the aetiology of deep vein thrombosis in Turkish patients. Materials and Methods: Our study involved the treatment of 63 patients, including follow-up in our outpatient department, between November 2006 and December 2007. There were 29 female and 34 male patients with a mean age of 49.35 + 14.19 (range 25 – 85 years). Deep vein thrombosis was identified using a Doppler-/ duplex sonogram. A small pulmonary embolism was present in 5 patients. Results: Follow-up was carried out in 58 patients (92.06%). The causes of deep vein thrombosis were detectable in 43 patients (68.25%) by anamnesis and physical examination. Immobilization was present in 33 patients (52.38%). A thrombophilia test was carried out in 29 patients. In 20 patients (31.74%) with the first manifestation of deep vein thrombosis, no cause for deep vein thrombosis could be found in the anamnesis. A thrombophilia test was carried out through analysis of Protein C, Protein S, APCR (Activated Protein C Resistance), and Factor V Leiden in 12 (60%) of these 20 patients. In 11 (91.66%) of these 12 patients, thrombophilia was positive. Conclusions: The main causes of deep vein thrombosis in the Turkish population were immobilization (52.38%) and thrombophilia (51.72%). The incidence of both causes is approximately equal. In the healthy Turkish population with the first manifestation of deep vein thrombosis, thrombophilia can be positive in 91.66% of patients.

Anahtar Kelime: Thrombophilia Venous Thrombosis Follow-Up Studies Ultrasonography, Doppler, Color Etiology

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ÇEBİ N, TANRIVERDİ S (2009). Aetiology of deep vein thrombosis in 63 Turkish patients. , 223 - 227.
Chicago	ÇEBİ Niyazi,TANRIVERDİ Süleyman Aetiology of deep vein thrombosis in 63 Turkish patients. (2009): 223 - 227.
MLA	ÇEBİ Niyazi,TANRIVERDİ Süleyman Aetiology of deep vein thrombosis in 63 Turkish patients. , 2009, ss.223 - 227.
AMA	ÇEBİ N,TANRIVERDİ S Aetiology of deep vein thrombosis in 63 Turkish patients. . 2009; 223 - 227.
Vancouver	ÇEBİ N,TANRIVERDİ S Aetiology of deep vein thrombosis in 63 Turkish patients. . 2009; 223 - 227.
IEEE	ÇEBİ N,TANRIVERDİ S "Aetiology of deep vein thrombosis in 63 Turkish patients." , ss.223 - 227, 2009.
ISNAD	ÇEBİ, Niyazi - TANRIVERDİ, Süleyman. "Aetiology of deep vein thrombosis in 63 Turkish patients". (2009), 223-227.

APA	ÇEBİ N, TANRIVERDİ S (2009). Aetiology of deep vein thrombosis in 63 Turkish patients. Turkish Journal of Medical Sciences, 39(2), 223 - 227.
Chicago	ÇEBİ Niyazi,TANRIVERDİ Süleyman Aetiology of deep vein thrombosis in 63 Turkish patients. Turkish Journal of Medical Sciences 39, no.2 (2009): 223 - 227.
MLA	ÇEBİ Niyazi,TANRIVERDİ Süleyman Aetiology of deep vein thrombosis in 63 Turkish patients. Turkish Journal of Medical Sciences, vol.39, no.2, 2009, ss.223 - 227.
AMA	ÇEBİ N,TANRIVERDİ S Aetiology of deep vein thrombosis in 63 Turkish patients. Turkish Journal of Medical Sciences. 2009; 39(2): 223 - 227.
Vancouver	ÇEBİ N,TANRIVERDİ S Aetiology of deep vein thrombosis in 63 Turkish patients. Turkish Journal of Medical Sciences. 2009; 39(2): 223 - 227.
IEEE	ÇEBİ N,TANRIVERDİ S "Aetiology of deep vein thrombosis in 63 Turkish patients." Turkish Journal of Medical Sciences, 39, ss.223 - 227, 2009.
ISNAD	ÇEBİ, Niyazi - TANRIVERDİ, Süleyman. "Aetiology of deep vein thrombosis in 63 Turkish patients". Turkish Journal of Medical Sciences 39/2 (2009), 223-227.