Yıl: 2009 Cilt: 33 Sayı: 6 Sayfa Aralığı: 813 - 823 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Antioxidant and anticholinesterase constituents of Salvia poculata

Öz:
Two triterpenoids, namely 2α,3α-dihydroxy-24-nor-4(23),12-oleanadien-28-oic acid (1) and ursolic acid (2); 4 flavonoids, namely 5-hydroxy-7,4’-dimethoxyflavone (3), cirsimaritin (4), eupatilin (5), and salvigenin (6); a diterpenoid, namely sclareol (7); and a steroid, namely β -sitosterol (8), were isolated from the aerial parts of Salvia poculata Nab., a Turkish endemic Salvia species. Total phenolic and flavonoid contents of the crude extract were determined as pyrocatechol and quercetin equivalents, respectively. The antioxidant activity of the crude extract and the isolated compounds (2-8) was established using β -carotene bleaching, superoxide anion radical, and ABTS cation radical scavenging activity. In addition, the anticholinesterase activity of the crude extract and the isolated compounds (2-8) against the enzymes acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) was determined. The phytochemistry and antioxidant and anticholinesterase activities of S. poculata were investigated for the first time in this study. The crude extract of S. poculata exhibited a significant antioxidant effect as well as butyrylcholinesterase inhibitory activity. Ursolic acid (2) and cirsimaritin (4) possessed high butyrylcholinesterase inhibitory activity.
Anahtar Kelime:

Konular: Mühendislik, Kimya
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA KOLAK U, HACIBEKİROĞLU I, Öztürk M, Özgökçe F, Topcu G, ULUBELEN A (2009). Antioxidant and anticholinesterase constituents of Salvia poculata. , 813 - 823.
Chicago KOLAK UFUK,HACIBEKİROĞLU Işıl,Öztürk Mehmet,Özgökçe Fevzi,Topcu Gulacti,ULUBELEN Ayhan Antioxidant and anticholinesterase constituents of Salvia poculata. (2009): 813 - 823.
MLA KOLAK UFUK,HACIBEKİROĞLU Işıl,Öztürk Mehmet,Özgökçe Fevzi,Topcu Gulacti,ULUBELEN Ayhan Antioxidant and anticholinesterase constituents of Salvia poculata. , 2009, ss.813 - 823.
AMA KOLAK U,HACIBEKİROĞLU I,Öztürk M,Özgökçe F,Topcu G,ULUBELEN A Antioxidant and anticholinesterase constituents of Salvia poculata. . 2009; 813 - 823.
Vancouver KOLAK U,HACIBEKİROĞLU I,Öztürk M,Özgökçe F,Topcu G,ULUBELEN A Antioxidant and anticholinesterase constituents of Salvia poculata. . 2009; 813 - 823.
IEEE KOLAK U,HACIBEKİROĞLU I,Öztürk M,Özgökçe F,Topcu G,ULUBELEN A "Antioxidant and anticholinesterase constituents of Salvia poculata." , ss.813 - 823, 2009.
ISNAD KOLAK, UFUK vd. "Antioxidant and anticholinesterase constituents of Salvia poculata". (2009), 813-823.
APA KOLAK U, HACIBEKİROĞLU I, Öztürk M, Özgökçe F, Topcu G, ULUBELEN A (2009). Antioxidant and anticholinesterase constituents of Salvia poculata. Turkish Journal of Chemistry, 33(6), 813 - 823.
Chicago KOLAK UFUK,HACIBEKİROĞLU Işıl,Öztürk Mehmet,Özgökçe Fevzi,Topcu Gulacti,ULUBELEN Ayhan Antioxidant and anticholinesterase constituents of Salvia poculata. Turkish Journal of Chemistry 33, no.6 (2009): 813 - 823.
MLA KOLAK UFUK,HACIBEKİROĞLU Işıl,Öztürk Mehmet,Özgökçe Fevzi,Topcu Gulacti,ULUBELEN Ayhan Antioxidant and anticholinesterase constituents of Salvia poculata. Turkish Journal of Chemistry, vol.33, no.6, 2009, ss.813 - 823.
AMA KOLAK U,HACIBEKİROĞLU I,Öztürk M,Özgökçe F,Topcu G,ULUBELEN A Antioxidant and anticholinesterase constituents of Salvia poculata. Turkish Journal of Chemistry. 2009; 33(6): 813 - 823.
Vancouver KOLAK U,HACIBEKİROĞLU I,Öztürk M,Özgökçe F,Topcu G,ULUBELEN A Antioxidant and anticholinesterase constituents of Salvia poculata. Turkish Journal of Chemistry. 2009; 33(6): 813 - 823.
IEEE KOLAK U,HACIBEKİROĞLU I,Öztürk M,Özgökçe F,Topcu G,ULUBELEN A "Antioxidant and anticholinesterase constituents of Salvia poculata." Turkish Journal of Chemistry, 33, ss.813 - 823, 2009.
ISNAD KOLAK, UFUK vd. "Antioxidant and anticholinesterase constituents of Salvia poculata". Turkish Journal of Chemistry 33/6 (2009), 813-823.