Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats

DURMUŞ, Ali Said; YAMAN, İhsan; HAN, Mehmet Cengiz

Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats

Ali Said DURMUŞ, (Fırat Üniversitesi, Veteriner Fakültesi, Cerrahi Anabilim Dalı, Elazığ, Türkiye)

Mehmet Cengiz HAN, (Fırat Üniversitesi, Veteriner Fakültesi, Cerrahi Anabilim Dalı, Elazığ, Türkiye)

İhsan YAMAN (Fırat Üniversitesi, Sivrice Meslek Yüksekokulu Elazığ, Türkiye)

Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi

6 0

Yıl: 2009 Cilt: 23 Sayı: 3 Sayfa Aralığı: 135 - 139 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats

Öz:

Bu çalışma ratlarda yanık yaralarının iyileşmesinde kollagenaz ve silver sulfadiazine’in (SSD) karşılaştırmasını yapmak için gerçekleştirildi. Altmış Wistar albino rat üç eşit gruba bölündü. Bütün ratların sırtlarında yanık modeli oluşturuldu. Yanık bölgeler günlük olarak, birinci, ikinci ve üçüncü gruplarda sırasıyla kollagenaz, SSD deri kremi ve cold cream (kontrol) ile kaplandılar. On ve 21 gün sonra histopatolojik muayeneler için ratlar anestezi altına alınarak her gruptan 10 hayvandan yanık uygulanan deri örnekleri alındı. Sonuç olarak, kollagenaz merhem uygulamasının rat modelinde deri yanıklarının iyileşmesi üzerinde anlamlı derecede etkili olduğu belirlenmiştir (P< 0.0001).

Anahtar Kelime: gümüş sülfadiyazin tedavi sıçan kollagenaz yanık

Konular: Veterinerlik

Ratlarda yanık yaralarının iyileşmesi üzerine kollagenaz ve silver sulfadiazine’in etkilerinin karşılaştırılması

Öz:

This experiment was conducted to compare collagenase the effects of ointment and silver sulfadiazine (SSD) on burned wounds for healing in rats. Sixty male Wistar albino rats were divided into three equal groups. A burned model was constituted on the back of all rats. The burned areas in the first, second and third groups were covered daily with collagenase, SSD skin cream and cold cream (control), respectively. Ten and 21 days later the rats were anaesthetized and the burned skin tissue samples of ten cases of each group were collected for histopathological examinations. In conclusion, application of collagenase ointment is significantly effective in healing of burned skin wounds in rat model (P< 0.0001).

Anahtar Kelime: rats collagenase burns silver sulfadiazine therapy

Konular: Veterinerlik

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Bibliyografik

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APA	DURMUŞ A, HAN M, YAMAN İ (2009). Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats. , 135 - 139.
Chicago	DURMUŞ Ali Said,HAN Mehmet Cengiz,YAMAN İhsan Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats. (2009): 135 - 139.
MLA	DURMUŞ Ali Said,HAN Mehmet Cengiz,YAMAN İhsan Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats. , 2009, ss.135 - 139.
AMA	DURMUŞ A,HAN M,YAMAN İ Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats. . 2009; 135 - 139.
Vancouver	DURMUŞ A,HAN M,YAMAN İ Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats. . 2009; 135 - 139.
IEEE	DURMUŞ A,HAN M,YAMAN İ "Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats." , ss.135 - 139, 2009.
ISNAD	DURMUŞ, Ali Said vd. "Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats". (2009), 135-139.

APA	DURMUŞ A, HAN M, YAMAN İ (2009). Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats. Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi, 23(3), 135 - 139.
Chicago	DURMUŞ Ali Said,HAN Mehmet Cengiz,YAMAN İhsan Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats. Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi 23, no.3 (2009): 135 - 139.
MLA	DURMUŞ Ali Said,HAN Mehmet Cengiz,YAMAN İhsan Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats. Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi, vol.23, no.3, 2009, ss.135 - 139.
AMA	DURMUŞ A,HAN M,YAMAN İ Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats. Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi. 2009; 23(3): 135 - 139.
Vancouver	DURMUŞ A,HAN M,YAMAN İ Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats. Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi. 2009; 23(3): 135 - 139.
IEEE	DURMUŞ A,HAN M,YAMAN İ "Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats." Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi, 23, ss.135 - 139, 2009.
ISNAD	DURMUŞ, Ali Said vd. "Comperative Evaluation of collagenase and silver sulfadiazine on burned wound healing in rats". Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi 23/3 (2009), 135-139.