The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats

KACAR, Cihan; ZONTURLU, Abuzer Kaffar; ÇITIL, MEHMET; KARAPEHLİVAN, Mahmut; ÖĞÜN, Metin; ARI, Umut Çağın

The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats

Cihan KAÇAR, (Kafkas Üniversitesi, Veteriner Fakültesi, Kars, Türkiye)

Abuzer Kaffar ZONTURLU, (Harran Üniversitesi, Veteriner Fakültesi, Şanlıurfa, Türkiye)

Mahmut KARAPEHLİVAN, (Kafkas Üniversitesi, Veteriner Fakültesi, Kars, Türkiye)

Umut Çağın ARI, (Kafkas Üniversitesi, Veteriner Fakültesi, Kars, Türkiye)

Metin ÖĞÜN, (Kafkas Üniversitesi, Veteriner Fakültesi, Kars, Türkiye)

Mehmet ÇİTİL (Kafkas Üniversitesi, Veteriner Fakültesi, Kars, Türkiye)

Turkish Journal of Veterinary and Animal Sciences

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Yıl: 2010 Cilt: 34 Sayı: 2 Sayfa Aralığı: 163 - 171 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats

Öz:

Bu çalışmada, gebeliğin son bir ayı içerisinde bulunan Halep (Damascus) keçilerinde L-carnitine uygulamalarının bazı biyokimyasal parametrelere etkisi araştırıldı. Gebeliğin son bir ayı içerisinde bulunan Grup I’deki keçilere (n = 13) bir hafta aralıklarla L-carnitine subkutan yolla uygulandı. Grup II’deki (n = 12) keçilere ise aynı dönemde subkutan yolla % 0,9’luk serum fizyolojik uygulandı. Grup I ve Grup II’deki keçilerde serum glukoz konsantrasyonları yönünden istatistiksel bir fark tespit edilmedi (P > 0,05). Serum β-hidroksibutirik asit (BHB) konsantrasyonunun her iki grupta doğuma kadar arttığı ve gruplar arasında istatistiksel bir fark olmadığı tespit edildi (P > 0,05). Serum NEFA (Non- Esterified Fatty Acid) konsantrasyonunun doğumdan iki hafta önce grup I’de daha düşük olduğu görüldü (P < 0,05). Gruplarda serum trigliserid ve serum kolestrol konsantrasyonları arasında istatistiksel bir fark tespit edilmedi (P > 0,05). L-carnitine uygulanan ve ikiz doğuran keçilerde serum glukoz konsantrasyonlarının doğumdan iki hafta (P < 0,01) ve doğumdan üç hafta (P < 0,05) önce kontrol grubunda ikiz doğuran keçilerden daha yüksek olduğu saptandı. Paranteral L-carnitine uygulamalarının ikiz doğum yapan keçilerde serum glukoz konsantrasyonunu arttırarak gebelik toksemisi gibi hastalıklara karşı koruyucu bir güç olabileceği sonucuna varıldı.

Anahtar Kelime: keçi kan serumu L-karnitin Damaskus (keçi ırkı) biyokimyasal parametreler doğum öncesi dönem enerji metabolizması doğum sonrası dönem gebelik keçi ırkları

Konular: Ziraat Mühendisliği

Gebe Halep (Damascus) keçilerinde L-carnitine uygulamalarının enerji metabolizmasına etkileri

Öz:

The aim of this study was to determine the effects of parenteral administration of L-carnitine on some biochemical parameters in Halep (Damascus) goats during the last month of pregnancy. L-carnitine was administrated to goats in group I (n = 13) by subcutaneous injections once a week during the last month of the pregnancy. Physiologic salt solution was administered to goats in group II (n = 12) by the same route during the same period. Differences of glucose concentration between groups were not significant (P > 0.05). Serum β-hydroxybutyric acid (BHB) concentrations in both groups increased until parturition. However, differences between groups were not significant (P > 0.05). Concentration of serum NEFA (Non Esterified Fatty Acid) in group I was lower compared to group II 2 weeks before parturition (P < 0.05). Differences of serum triglyceride and cholesterol concentration between groups were not significant (P > 0.05). Level of glucose concentration in L-carnitine administered goats with twin kids was higher than the controls with twin kids in the $2^{nd}$ (P < 0.01) and $3^{rd}$ weeks (P < 0.05) before parturition. It was concluded that parenteral administration of L-carnitine might be a protective measure against pregnancy toxemia (ketosis) via increasing serum glucose concentration in goats with twin pregnancy.

Anahtar Kelime: L-carnitine Damascus (goat breed) biochemical parameters prepartum period energy metabolism postpartum period pregnancy goat breeds goats blood serum

Konular: Ziraat Mühendisliği

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	KACAR C, ZONTURLU A, KARAPEHLİVAN M, ARI U, ÖĞÜN M, ÇITIL M (2010). The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats. , 163 - 171.
Chicago	KACAR Cihan,ZONTURLU Abuzer Kaffar,KARAPEHLİVAN Mahmut,ARI Umut Çağın,ÖĞÜN Metin,ÇITIL MEHMET The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats. (2010): 163 - 171.
MLA	KACAR Cihan,ZONTURLU Abuzer Kaffar,KARAPEHLİVAN Mahmut,ARI Umut Çağın,ÖĞÜN Metin,ÇITIL MEHMET The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats. , 2010, ss.163 - 171.
AMA	KACAR C,ZONTURLU A,KARAPEHLİVAN M,ARI U,ÖĞÜN M,ÇITIL M The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats. . 2010; 163 - 171.
Vancouver	KACAR C,ZONTURLU A,KARAPEHLİVAN M,ARI U,ÖĞÜN M,ÇITIL M The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats. . 2010; 163 - 171.
IEEE	KACAR C,ZONTURLU A,KARAPEHLİVAN M,ARI U,ÖĞÜN M,ÇITIL M "The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats." , ss.163 - 171, 2010.
ISNAD	KACAR, Cihan vd. "The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats". (2010), 163-171.

APA	KACAR C, ZONTURLU A, KARAPEHLİVAN M, ARI U, ÖĞÜN M, ÇITIL M (2010). The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats. Turkish Journal of Veterinary and Animal Sciences, 34(2), 163 - 171.
Chicago	KACAR Cihan,ZONTURLU Abuzer Kaffar,KARAPEHLİVAN Mahmut,ARI Umut Çağın,ÖĞÜN Metin,ÇITIL MEHMET The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats. Turkish Journal of Veterinary and Animal Sciences 34, no.2 (2010): 163 - 171.
MLA	KACAR Cihan,ZONTURLU Abuzer Kaffar,KARAPEHLİVAN Mahmut,ARI Umut Çağın,ÖĞÜN Metin,ÇITIL MEHMET The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats. Turkish Journal of Veterinary and Animal Sciences, vol.34, no.2, 2010, ss.163 - 171.
AMA	KACAR C,ZONTURLU A,KARAPEHLİVAN M,ARI U,ÖĞÜN M,ÇITIL M The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats. Turkish Journal of Veterinary and Animal Sciences. 2010; 34(2): 163 - 171.
Vancouver	KACAR C,ZONTURLU A,KARAPEHLİVAN M,ARI U,ÖĞÜN M,ÇITIL M The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats. Turkish Journal of Veterinary and Animal Sciences. 2010; 34(2): 163 - 171.
IEEE	KACAR C,ZONTURLU A,KARAPEHLİVAN M,ARI U,ÖĞÜN M,ÇITIL M "The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats." Turkish Journal of Veterinary and Animal Sciences, 34, ss.163 - 171, 2010.
ISNAD	KACAR, Cihan vd. "The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats". Turkish Journal of Veterinary and Animal Sciences 34/2 (2010), 163-171.