The objective of this study is to determine the architectural space performance of a cultural-historical building re-used for a different function other than its original construction-purpose. The problem is considered to be the determination of the functional and spatial requirements of the new function of the building and the investigation on the level of sufficiency of the existing spaces to meet these requirements. The adaptability level of the building for the given functional requirements was obtained from observations, interviews and polls applied to the current users of the building. Dealing with the performance of a re-used cultural-historical building in terms of maintaining the preservation of it was evaluated to be the performance approach specialized in this study. The building of the Chamber of Architects, or the Architects’ House in Konya, a historic building, is investigated to determine the level of its spatial performance (technical and functional) and its level of adaptability to respond the new functional requirements, and thus, the advantages and disadvantages of the assigned function were revealed. Arrangement of re-used buildings to serve the requirements of new users/new functions and reception of pleasant user comments about their spatial performance are significant concepts for the continuity and sustainability of the reused building’s function. Evaluation of space performances of reused buildings is beneficial in terms of taking precautions to provide the continuity of the function assigned for the building. Additionally, the components that should be analyzed during the adaptation process of the cultural-historical buildings having reusability potential are determined by the help of this evaluation and listed as; (i) the position and the functional adaptation of the building, (ii) the organization and the quality of the existing spaces, (iii) the space requirements of the assigned function, and (iv) the evaluation of the adaptability level.