High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients

BACKGROUND AND AIM: Obstructive sleep apnea (OSA), having an increased inflammatory state due to an imbalance between sympathetic and parasympathetic activity, intermittent hypoxia, and increased cytokines, may aggravate the immune response for COVID-19 infection. Our aim was to evaluate the effect of OSA upon inflammatory response and length of stay in patients with favorable outcomes. METHODS: Patients admitted to an outpatient clinic after being hospitalized for treatment of COVID-19 were included consecutively in this cross-sectional multicenter observational study. STOP-Bang Questionnaire and a cut-off value of 3 points were used to identify patients with a high risk of OSA. RESULTS: Study population consisted of 201 patients with a median STOP-Bang score of 2.0 (1.0–4.0) points. According to the cut-off value of 3 points, 94 (46.8%) patients were classified as high-risk OSA patients. High-risk OSA patients were older, had many comorbidities such as hypertension, coronary artery disease, and diabetes mellitus, had higher serum D-dimer, ferritin, Creactive protein, and procalcitonin measurements, and had a longer hospital stay. Possible risk factors associated with length of stay were age, lymphocyte count, and total STOP-Bang score. Multivariable analysis revealed that a 1 point increase in STOPBang score results in a 0.43 day longer hospital stay. CONCLUSIONS: Prevalence of OSA within COVID-19 patients with favorable outcomes is similar to the general population. However, the length of stay is related to the presence of high-risk OSA. Our study, therefore, suggests that OSA is related to delayed improvement of COVID-19 infection.

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APA	Acet Öztürk N, Aydin Guclu O, s, SENGOREN DİKİS Ö, Sali M, Durmaz D, TASBAS E, Ertem Cengiz A, Çetiner Bahçetepe D, AYDIN A, yavuz z, Beyeç M, Burgazlıoğlu B, Zeytinoglu D, Terzi O, Demirdöğen E, Gorek Dilektasli A, COŞKUN F, Ediger D, Uzaslan E, Karadağ M, Ursavas A (2022). High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients. , 95 - 100. 10.14744/ejp.2022.9921
Chicago	Acet Öztürk Nilüfer Aylin,Aydin Guclu Ozge, serap,SENGOREN DİKİS ÖZLEM,Sali Mürsel,Durmaz Dilber,TASBAS ESİN,Ertem Cengiz Arzu,Çetiner Bahçetepe Dilek,AYDIN Asena,yavuz zekiye,Beyeç Melike,Burgazlıoğlu Başak,Zeytinoglu Duygu,Terzi Orkun Eray,Demirdöğen Ezgi,Gorek Dilektasli Asli,COŞKUN FUNDA,Ediger Dane,Uzaslan Esra,Karadağ Mehmet,Ursavas Ahmet High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients. (2022): 95 - 100. 10.14744/ejp.2022.9921
MLA	Acet Öztürk Nilüfer Aylin,Aydin Guclu Ozge, serap,SENGOREN DİKİS ÖZLEM,Sali Mürsel,Durmaz Dilber,TASBAS ESİN,Ertem Cengiz Arzu,Çetiner Bahçetepe Dilek,AYDIN Asena,yavuz zekiye,Beyeç Melike,Burgazlıoğlu Başak,Zeytinoglu Duygu,Terzi Orkun Eray,Demirdöğen Ezgi,Gorek Dilektasli Asli,COŞKUN FUNDA,Ediger Dane,Uzaslan Esra,Karadağ Mehmet,Ursavas Ahmet High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients. , 2022, ss.95 - 100. 10.14744/ejp.2022.9921
AMA	Acet Öztürk N,Aydin Guclu O, s,SENGOREN DİKİS Ö,Sali M,Durmaz D,TASBAS E,Ertem Cengiz A,Çetiner Bahçetepe D,AYDIN A,yavuz z,Beyeç M,Burgazlıoğlu B,Zeytinoglu D,Terzi O,Demirdöğen E,Gorek Dilektasli A,COŞKUN F,Ediger D,Uzaslan E,Karadağ M,Ursavas A High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients. . 2022; 95 - 100. 10.14744/ejp.2022.9921
Vancouver	Acet Öztürk N,Aydin Guclu O, s,SENGOREN DİKİS Ö,Sali M,Durmaz D,TASBAS E,Ertem Cengiz A,Çetiner Bahçetepe D,AYDIN A,yavuz z,Beyeç M,Burgazlıoğlu B,Zeytinoglu D,Terzi O,Demirdöğen E,Gorek Dilektasli A,COŞKUN F,Ediger D,Uzaslan E,Karadağ M,Ursavas A High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients. . 2022; 95 - 100. 10.14744/ejp.2022.9921
IEEE	Acet Öztürk N,Aydin Guclu O, s,SENGOREN DİKİS Ö,Sali M,Durmaz D,TASBAS E,Ertem Cengiz A,Çetiner Bahçetepe D,AYDIN A,yavuz z,Beyeç M,Burgazlıoğlu B,Zeytinoglu D,Terzi O,Demirdöğen E,Gorek Dilektasli A,COŞKUN F,Ediger D,Uzaslan E,Karadağ M,Ursavas A "High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients." , ss.95 - 100, 2022. 10.14744/ejp.2022.9921
ISNAD	Acet Öztürk, Nilüfer Aylin vd. "High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients". (2022), 95-100. https://doi.org/10.14744/ejp.2022.9921

APA	Acet Öztürk N, Aydin Guclu O, s, SENGOREN DİKİS Ö, Sali M, Durmaz D, TASBAS E, Ertem Cengiz A, Çetiner Bahçetepe D, AYDIN A, yavuz z, Beyeç M, Burgazlıoğlu B, Zeytinoglu D, Terzi O, Demirdöğen E, Gorek Dilektasli A, COŞKUN F, Ediger D, Uzaslan E, Karadağ M, Ursavas A (2022). High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients. Eurasian Journal of Pulmonology, 24(2), 95 - 100. 10.14744/ejp.2022.9921
Chicago	Acet Öztürk Nilüfer Aylin,Aydin Guclu Ozge, serap,SENGOREN DİKİS ÖZLEM,Sali Mürsel,Durmaz Dilber,TASBAS ESİN,Ertem Cengiz Arzu,Çetiner Bahçetepe Dilek,AYDIN Asena,yavuz zekiye,Beyeç Melike,Burgazlıoğlu Başak,Zeytinoglu Duygu,Terzi Orkun Eray,Demirdöğen Ezgi,Gorek Dilektasli Asli,COŞKUN FUNDA,Ediger Dane,Uzaslan Esra,Karadağ Mehmet,Ursavas Ahmet High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients. Eurasian Journal of Pulmonology 24, no.2 (2022): 95 - 100. 10.14744/ejp.2022.9921
MLA	Acet Öztürk Nilüfer Aylin,Aydin Guclu Ozge, serap,SENGOREN DİKİS ÖZLEM,Sali Mürsel,Durmaz Dilber,TASBAS ESİN,Ertem Cengiz Arzu,Çetiner Bahçetepe Dilek,AYDIN Asena,yavuz zekiye,Beyeç Melike,Burgazlıoğlu Başak,Zeytinoglu Duygu,Terzi Orkun Eray,Demirdöğen Ezgi,Gorek Dilektasli Asli,COŞKUN FUNDA,Ediger Dane,Uzaslan Esra,Karadağ Mehmet,Ursavas Ahmet High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients. Eurasian Journal of Pulmonology, vol.24, no.2, 2022, ss.95 - 100. 10.14744/ejp.2022.9921
AMA	Acet Öztürk N,Aydin Guclu O, s,SENGOREN DİKİS Ö,Sali M,Durmaz D,TASBAS E,Ertem Cengiz A,Çetiner Bahçetepe D,AYDIN A,yavuz z,Beyeç M,Burgazlıoğlu B,Zeytinoglu D,Terzi O,Demirdöğen E,Gorek Dilektasli A,COŞKUN F,Ediger D,Uzaslan E,Karadağ M,Ursavas A High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients. Eurasian Journal of Pulmonology. 2022; 24(2): 95 - 100. 10.14744/ejp.2022.9921
Vancouver	Acet Öztürk N,Aydin Guclu O, s,SENGOREN DİKİS Ö,Sali M,Durmaz D,TASBAS E,Ertem Cengiz A,Çetiner Bahçetepe D,AYDIN A,yavuz z,Beyeç M,Burgazlıoğlu B,Zeytinoglu D,Terzi O,Demirdöğen E,Gorek Dilektasli A,COŞKUN F,Ediger D,Uzaslan E,Karadağ M,Ursavas A High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients. Eurasian Journal of Pulmonology. 2022; 24(2): 95 - 100. 10.14744/ejp.2022.9921
IEEE	Acet Öztürk N,Aydin Guclu O, s,SENGOREN DİKİS Ö,Sali M,Durmaz D,TASBAS E,Ertem Cengiz A,Çetiner Bahçetepe D,AYDIN A,yavuz z,Beyeç M,Burgazlıoğlu B,Zeytinoglu D,Terzi O,Demirdöğen E,Gorek Dilektasli A,COŞKUN F,Ediger D,Uzaslan E,Karadağ M,Ursavas A "High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients." Eurasian Journal of Pulmonology, 24, ss.95 - 100, 2022. 10.14744/ejp.2022.9921
ISNAD	Acet Öztürk, Nilüfer Aylin vd. "High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients". Eurasian Journal of Pulmonology 24/2 (2022), 95-100. https://doi.org/10.14744/ejp.2022.9921