Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia

BAHADIR ACIKARA, ÖZLEM; ÇİTOĞLU, Saltan Gülçin; DALLACQUA, Atefano

Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia

Saltan Gülçin ÇİTOĞLU, (Ankara Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, Ankara, Türkiye)

ÖZLEM BAHADIR ACIKARA, (Ankara Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, Ankara, Türkiye)

Atefano DALLACQUA (Univercity of Degli Studi di Padova, Department, di Scienze Farmaceutiche, Natural Lab. Via Marzolo, Italy)

Turkish Journal of Pharmaceutical Sciences

8 2

Yıl: 2010 Cilt: 7 Sayı: 3 Sayfa Aralığı: 205 - 212 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia

Öz:

Scorzonera latifolia (Fisch. & Mey.) DC. orta ve doğu Anadolu ’da yetişen gok yilhk bir bitkidir.Bu bitkinin köklerinden Türk halk tıbbında analjezik olarak kullamlan, yah sakızi olarak isimlendirilen geleneksel bir sahz elde edilmektedir. Bu gahsmada, S latifolia köklerinden elde edilen metanollü ekstre kimyasal bileşimi agisından araştinlmistır. İzole edilen bileşikler (±) hidrangenol ve (-)-skorzotomentozin 4'-0-P-glukopiranozit olarak tammlanmistır. Bileşiklerin yapılan spektroskopik metotlar ('H-NMR, 13C-NMR, HMBC, HSQQ COSY, TOCSY, NOESY, DEPT) kullamlarak aydınlatılmis ve literatiir bilgileriyle doğrulanmistır.

Anahtar Kelime:

Konular: Farmakoloji ve Eczacılık

Scorzonera latifolia köklerinden izole edilen dihidroizokumarin türevi bileşikler

Öz:

Scorzonera latifolia (Fisch. & Mey.) DC. is a perennial herb that grows in central and eastern region of Anatolia, Turkey. A traditional mastic named yah sakızı has been prepared from the roots of this plant and used as an analgesic in Turkish folk medicine. In this study, the methanolic extract obtained from the roots of S. latifolia were investigated for the chemical composition. Two dihydroisocoumarin derivatives were isolated from the roots. The compounds were identified as (±) hydrangenol and (-)-scorzotomentosin 4'-0-P-glucopyranoside. The structures were determined using spectroscopic methods ('H-NMR, 13C-NMR, HMBC, HSQQ COSY, TOCSY, NOESY, DEPT) and chemical correlations with known compounds that have been described in the literature.

Anahtar Kelime:

Konular: Farmakoloji ve Eczacılık

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ÇİTOĞLU S, BAHADIR ACIKARA Ö, DALLACQUA A (2010). Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia. , 205 - 212.
Chicago	ÇİTOĞLU Saltan Gülçin,BAHADIR ACIKARA ÖZLEM,DALLACQUA Atefano Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia. (2010): 205 - 212.
MLA	ÇİTOĞLU Saltan Gülçin,BAHADIR ACIKARA ÖZLEM,DALLACQUA Atefano Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia. , 2010, ss.205 - 212.
AMA	ÇİTOĞLU S,BAHADIR ACIKARA Ö,DALLACQUA A Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia. . 2010; 205 - 212.
Vancouver	ÇİTOĞLU S,BAHADIR ACIKARA Ö,DALLACQUA A Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia. . 2010; 205 - 212.
IEEE	ÇİTOĞLU S,BAHADIR ACIKARA Ö,DALLACQUA A "Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia." , ss.205 - 212, 2010.
ISNAD	ÇİTOĞLU, Saltan Gülçin vd. "Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia". (2010), 205-212.

APA	ÇİTOĞLU S, BAHADIR ACIKARA Ö, DALLACQUA A (2010). Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia. Turkish Journal of Pharmaceutical Sciences, 7(3), 205 - 212.
Chicago	ÇİTOĞLU Saltan Gülçin,BAHADIR ACIKARA ÖZLEM,DALLACQUA Atefano Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia. Turkish Journal of Pharmaceutical Sciences 7, no.3 (2010): 205 - 212.
MLA	ÇİTOĞLU Saltan Gülçin,BAHADIR ACIKARA ÖZLEM,DALLACQUA Atefano Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia. Turkish Journal of Pharmaceutical Sciences, vol.7, no.3, 2010, ss.205 - 212.
AMA	ÇİTOĞLU S,BAHADIR ACIKARA Ö,DALLACQUA A Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia. Turkish Journal of Pharmaceutical Sciences. 2010; 7(3): 205 - 212.
Vancouver	ÇİTOĞLU S,BAHADIR ACIKARA Ö,DALLACQUA A Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia. Turkish Journal of Pharmaceutical Sciences. 2010; 7(3): 205 - 212.
IEEE	ÇİTOĞLU S,BAHADIR ACIKARA Ö,DALLACQUA A "Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia." Turkish Journal of Pharmaceutical Sciences, 7, ss.205 - 212, 2010.
ISNAD	ÇİTOĞLU, Saltan Gülçin vd. "Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia". Turkish Journal of Pharmaceutical Sciences 7/3 (2010), 205-212.