In vitro Biological Activities of Different Extracts from Alcea dissecta

Turgut TAŞKIN, (Marmara Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, İstanbul, Türkiye)
Dilay KAHVECİOĞLU, (Marmara Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, İstanbul, Türkiye)
Emir Alper TÜRKOĞLU, (Sağlık Bilimleri Üniversitesi, Eczacılık Fakültesi, Farmasötik Biyoteknoloji Anabilim Dalı, İstanbul, Türkiye)
Ahmet DOĞAN, (Marmara Üniversitesi, Eczacılık Fakültesi, Farmasötik Botanik Anabilim Dalı, İstanbul, Türkiye)
Müslüm KUZU (Karabük Üniversitesi, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümü, Karabük, Türkiye)
Clinical and Experimental Health Sciences
2 0
Yıl: 2022 Cilt: 12 Sayı: 1 Sayfa Aralığı: 53 - 60 Metin Dili: İngilizce DOI: 10.33808/clinexphealthsci.787845 İndeks Tarihi: 03-10-2022

In vitro Biological Activities of Different Extracts from Alcea dissecta

Öz:
Objective: Alcea genus belongs to Malvaceae family and this genus is represented by 85 taxa in the world and 21 taxa in the Flora of Turkey.The flowers of Alcea genus contain plenty of mucilage and are used for the treatment of respiratory diseases such as asthma and cough.Alcea dissecta is known as ‘Govik, Hiro, Hero’ in Turkey, and the flowers and leaves of this species have been used in the treatment of asthma,injury, colds, and gastrointestinal diseases in Turkey. To the best of our knowledge, there is no report on the effect of extraction methods onthe biological activity of this plant. In addition, although this species is being used as a medical plant, there is no study of the antioxidant, antiurease,esterase, and anticholinesterase activity of the plant. Therefore, the aim of this study was to evaluate in vitro antioxidant, anti-urease,esterase, anticholinesterase activities of Alcea dissecta using a variety of extracts.Methods: The antioxidant activities of different extracts were examined by DPPH, ABTS, FRAP, and CUPRAC methods. The total phenoliccompounds contained in the extracts were determined using the Folin-Ciocalteu reagent (FCR) method. Anti-urease and anticholinesteraseactivities of different extracts were evaluated by indophenol and Ellman methods respectively. In addition, esterase activities of plant extractswere determined.Results: In the present study, ethanol:water (1:1, v/v) and chloroform extracts obtained maceration method showed stronger DPPH and ABTSradical scavenging activity than other extracts. The chloroform extract obtained Soxhlet method was found to have higher FRAP and CUPRACvalues than other extracts. It was also found that the ethanol extract obtained maceration method showed the most potent anti-urease andanticholinesterase activity. According to the results, the strongest inhibitory effect on both hCA I and II isoenzymes was shown by the petroleumether extract obtained Soxhlet method.Conclusion: As a result, it was determined that different plant extracts have antioxidant, anti-urease, esterase, anticholinesterase activities. Inaddition, the data obtained from this study will shed light on future research on the biological activities of this species.
Anahtar Kelime: Alcea dissecta biological activity medicinal plant

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA taskin t, KAHVECİOĞLU D, Türkoğlu E, doğan a, KUZU M (2022). In vitro Biological Activities of Different Extracts from Alcea dissecta. , 53 - 60. 10.33808/clinexphealthsci.787845
Chicago taskin turgut,KAHVECİOĞLU DİLAY,Türkoğlu Emir Alper,doğan ahmet,KUZU Müslüm In vitro Biological Activities of Different Extracts from Alcea dissecta. (2022): 53 - 60. 10.33808/clinexphealthsci.787845
MLA taskin turgut,KAHVECİOĞLU DİLAY,Türkoğlu Emir Alper,doğan ahmet,KUZU Müslüm In vitro Biological Activities of Different Extracts from Alcea dissecta. , 2022, ss.53 - 60. 10.33808/clinexphealthsci.787845
AMA taskin t,KAHVECİOĞLU D,Türkoğlu E,doğan a,KUZU M In vitro Biological Activities of Different Extracts from Alcea dissecta. . 2022; 53 - 60. 10.33808/clinexphealthsci.787845
Vancouver taskin t,KAHVECİOĞLU D,Türkoğlu E,doğan a,KUZU M In vitro Biological Activities of Different Extracts from Alcea dissecta. . 2022; 53 - 60. 10.33808/clinexphealthsci.787845
IEEE taskin t,KAHVECİOĞLU D,Türkoğlu E,doğan a,KUZU M "In vitro Biological Activities of Different Extracts from Alcea dissecta." , ss.53 - 60, 2022. 10.33808/clinexphealthsci.787845
ISNAD taskin, turgut vd. "In vitro Biological Activities of Different Extracts from Alcea dissecta". (2022), 53-60. https://doi.org/10.33808/clinexphealthsci.787845
APA taskin t, KAHVECİOĞLU D, Türkoğlu E, doğan a, KUZU M (2022). In vitro Biological Activities of Different Extracts from Alcea dissecta. Clinical and Experimental Health Sciences, 12(1), 53 - 60. 10.33808/clinexphealthsci.787845
Chicago taskin turgut,KAHVECİOĞLU DİLAY,Türkoğlu Emir Alper,doğan ahmet,KUZU Müslüm In vitro Biological Activities of Different Extracts from Alcea dissecta. Clinical and Experimental Health Sciences 12, no.1 (2022): 53 - 60. 10.33808/clinexphealthsci.787845
MLA taskin turgut,KAHVECİOĞLU DİLAY,Türkoğlu Emir Alper,doğan ahmet,KUZU Müslüm In vitro Biological Activities of Different Extracts from Alcea dissecta. Clinical and Experimental Health Sciences, vol.12, no.1, 2022, ss.53 - 60. 10.33808/clinexphealthsci.787845
AMA taskin t,KAHVECİOĞLU D,Türkoğlu E,doğan a,KUZU M In vitro Biological Activities of Different Extracts from Alcea dissecta. Clinical and Experimental Health Sciences. 2022; 12(1): 53 - 60. 10.33808/clinexphealthsci.787845
Vancouver taskin t,KAHVECİOĞLU D,Türkoğlu E,doğan a,KUZU M In vitro Biological Activities of Different Extracts from Alcea dissecta. Clinical and Experimental Health Sciences. 2022; 12(1): 53 - 60. 10.33808/clinexphealthsci.787845
IEEE taskin t,KAHVECİOĞLU D,Türkoğlu E,doğan a,KUZU M "In vitro Biological Activities of Different Extracts from Alcea dissecta." Clinical and Experimental Health Sciences, 12, ss.53 - 60, 2022. 10.33808/clinexphealthsci.787845
ISNAD taskin, turgut vd. "In vitro Biological Activities of Different Extracts from Alcea dissecta". Clinical and Experimental Health Sciences 12/1 (2022), 53-60. https://doi.org/10.33808/clinexphealthsci.787845
Sayfa Oluşturulma Tarihi
24-04-2024 14:33

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