Aim: Lymphadenopathies (LAP), which is the most common cause presentation in childhood, can usually be diagnosed by history and physical examination but many tests are requested due to the fear of malignant disease and patients are followed up for a long time. It was aimed to evaluate the cases referred to Pediatric Oncology outpatient clinic of our center with the suspicion of malignancy due to LAP between 2012-2021 by analyzing the file data, retrospectively. Method: Demographic data of the patients, examinations, number of outpatient visits, follow-up periods, contribution of additional tests to the diagnosis and diagnoses were analyzed in three groups. Group A is the benign group with the cases with a LAP size of <2 cm, group B is the other benign group includes LAP size >2cm and group C is the malignant disease group. Results: In group C, the median age was statistically significantly higher than the other groups (p<0.001). Additional finding was statistically significant in more patients in the malignant group (p=0.002). It was seen that there were statistically significantly less number of admissions in the malignant group (p=0.026). Conclusion: While the most common cause of childhood LAP etiology is benign causes, the most important steps in diagnosis are history and physical examination. Apart from selected patients, additional tests should be requested due to both radiation exposure and the stress that will cause in families, and we think that the follow-up period should not be kept too long by evaluating on a case-by-case basis.