The purpose of lean thinking is to get rid of as much waste as possible. Eliminating wasteful activities such as transport, overproduction, waiting, defects, overprocessing, inventory and movement is one of the most important prerequisites in a successful company. This concept is an integral part of lean thinking, and it helps increase profitability. Material picking costs constitute approximately 55%-60% of the total costs related to warehouse operations [1]. The purpose of this article is to develop an information system that finds the shortest path for the responsible personnel to collect the materials required for production from the stock addresses in the warehouse, determines the number of picking boxes required for these materials, and provides the material sequences within the box (in-box sequences). With this developed information system, it will be possible to reduce material picking costs by eliminating wasteful activities such as transport, waiting and movement. The implementation of the developed information system is carried out in a company that produces electromechanical products in Ankara. With the Material Picking Information Systems (MPIS) presented in this article, up to 50% improvement has been achieved in terms of the distance and time spent by the personnel and the model has been validated.