Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review
Yıl: 2023 Cilt: 12 Sayı: 1 Sayfa Aralığı: 31 - 42 Metin Dili: İngilizce DOI: 10.5336/pharmsci.2022-91528 İndeks Tarihi: 24-05-2023
Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review
Öz: Ginkgo biloba L. is considered one of the oldest trees in the world and has been used for thousands of years for its variety of pharmacological effects. It is commonly known as ginkgo. Leaf extracts of this fossil tree have been standardized and patented under the name EGb761. EGb761 mainly consists of terpene trilactones which are unique to this species and flavone glycosides. It is sup- ported by scientific research that these chemical components are re- sponsible for the pharmacological effects of the tree.G. biloba L. has gained interest as a therapeutic plant for its favorable effects in cog- nitive impairment and neurodegenerative disorders like dementia. Its beneficial impacts on a wide range of pathological conditions, in- cluding cardiovascular health, asthma, psychiatric disorders, skin problems, and glaucoma as well as antioxidant, anti-inflammatory, anticancer and hepatoprotective activities, have been reported through experimental and clinical research. Ginkgo is generally well toler- ated but when combined with warfarin or other antiplatelet medica- tions, it can increase the risk of bleeding. This review mainly focuses on recent studies of pharmacological effects of G. biloba L. and in- dicates that G. biloba L. might be beneficial in the prevention and improvement of neurological, cardiovascular, pulmonary, ocular, metabolic, mental disorders also have anticancer and antimicrobial properties however further studies and clinical trials are necessary to confirm the safety and efficacy ofG. biloba L. in order to guide med- ical use.
Anahtar Kelime: Ginkgo biloba L. Ağacının Terapötik Uygulamaları: Sistematik Derleme
Öz: Ginkgo biloba L., dünyanın en eski a ğaçlarından biri olarak kabul edilir ve çeşitli farmakolojik etkileri nedeniyle binlerce yıldır kul- lanılmaktadır. Genellikle ginkgo olarak bilinmektedir. Bu fosil ağacın kendine has yapraklarının ekstreleri standardize edilmiş ve EGb761 adı ile patent almıştır. EGb761 esas olarak terpen trilaktonlar ve flavon gli- kozitlerinden oluşur, G. biloba ağacının farmakolojik etkilerinden bu kimyasal bileşenlerin sorumlu oldu ğu bilimsel ara ştırmalarla destek- lenmektedir. G. biloba L., bilişsel bozulma ve bunama gibi nörodeje- neratif bozukluklarda olumlu etkileri nedeniyle terapötik bir bitki olarak ilgi görmüştür. Kardiyovasküler sağlık, astım, psikiyatrik bozukluklar, cilt sorunları ve glokom dâhil olmak üzere çok çe şitli patolojik du- rumlar üzerindeki yararlı etkilerinin yanı sıra antioksidan, antiinflama- tuar, antikanser ve hepatoprotektif aktiviteleri deneysel ve klinik araştırmalar yoluyla rapor edilmiştir. G. biloba L. genellikle iyi tolere edilir, ancak varfarin veya di ğer antiplatelet ilaçlarla birlikte kullan ıl- dığında kanama riskini artırabilir. Bu derleme, temel olarak G. biloba L. bitkisinin farmakolojik etkilerine ili şkin son çal ışmalara odaklan- maktadır ve G. biloba L. bitkisinin nörolojik, kardiyovasküler, pulmo- ner, oküler, metabolik, zihinsel bozukluklar ın önlenmesinde ve iyileştirilmesinde faydalı olabileceğini, ayrıca antikanser ve antimik- robiyal özelliklere sahip oldu ğunu, ancak G. biloba L. bitkisinin gü- venliğini ve etkinliğini doğrulamak ve tıbbi kullanıma geçebilmek için daha fazla araştırma ve daha ileri klinik çalışmaların gerekli olduğunu ortaya koymaktadı
Anahtar Kelime: Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
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| APA | Öztürk S, Sarı A (2023). Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review. , 31 - 42. 10.5336/pharmsci.2022-91528 |
| Chicago | Öztürk Sena,Sarı Aynur Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review. (2023): 31 - 42. 10.5336/pharmsci.2022-91528 |
| MLA | Öztürk Sena,Sarı Aynur Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review. , 2023, ss.31 - 42. 10.5336/pharmsci.2022-91528 |
| AMA | Öztürk S,Sarı A Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review. . 2023; 31 - 42. 10.5336/pharmsci.2022-91528 |
| Vancouver | Öztürk S,Sarı A Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review. . 2023; 31 - 42. 10.5336/pharmsci.2022-91528 |
| IEEE | Öztürk S,Sarı A "Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review." , ss.31 - 42, 2023. 10.5336/pharmsci.2022-91528 |
| ISNAD | Öztürk, Sena - Sarı, Aynur. "Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review". (2023), 31-42. https://doi.org/10.5336/pharmsci.2022-91528 |
| APA | Öztürk S, Sarı A (2023). Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review. Literatür Eczacılık Bilimleri Dergisi, 12(1), 31 - 42. 10.5336/pharmsci.2022-91528 |
| Chicago | Öztürk Sena,Sarı Aynur Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review. Literatür Eczacılık Bilimleri Dergisi 12, no.1 (2023): 31 - 42. 10.5336/pharmsci.2022-91528 |
| MLA | Öztürk Sena,Sarı Aynur Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review. Literatür Eczacılık Bilimleri Dergisi, vol.12, no.1, 2023, ss.31 - 42. 10.5336/pharmsci.2022-91528 |
| AMA | Öztürk S,Sarı A Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review. Literatür Eczacılık Bilimleri Dergisi. 2023; 12(1): 31 - 42. 10.5336/pharmsci.2022-91528 |
| Vancouver | Öztürk S,Sarı A Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review. Literatür Eczacılık Bilimleri Dergisi. 2023; 12(1): 31 - 42. 10.5336/pharmsci.2022-91528 |
| IEEE | Öztürk S,Sarı A "Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review." Literatür Eczacılık Bilimleri Dergisi, 12, ss.31 - 42, 2023. 10.5336/pharmsci.2022-91528 |
| ISNAD | Öztürk, Sena - Sarı, Aynur. "Therapeutic Applications of Ginkgo biloba L. Tree: Systemic Review". Literatür Eczacılık Bilimleri Dergisi 12/1 (2023), 31-42. https://doi.org/10.5336/pharmsci.2022-91528 |
