Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria
Yıl: 2023 Cilt: 53 Sayı: 1 Sayfa Aralığı: 45 - 50 Metin Dili: İngilizce DOI: 10.26650/IstanbulJPharm.2023.1156339 İndeks Tarihi: 30-05-2023
Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria
Öz: Background and Aims: Gram-negative bacteria are important pathogens that can cause community- and hospital-acquired infections as well as opportunistic infections, with antimicrobial resistance in Gram-negative bacteria becoming a growing crisis in clinical medicine. Biofilm formation is one of the mechanisms of bacterial resistance, which makes bacteria less susceptible to antimicrobial agents and unable to be killed by host immune mechanisms. Therefore, this study investigates the antimicrobial resistances and biofilm-forming abilities of a total of 98 Gram-negative strains isolated from various clinical specimens. Methods: A disc diffusion assay was performed to detect the susceptibility profiles of 98 Gram-negative strains. The biofilmforming abilities of strains were also determined using the Crystal Violet assay. Results: Concerning the disc diffusion assay, most of the isolates were found to be resistant to carbapenems, with more than 90% of Acinetobacter baumannii, Klebsiella pneumoniae and Escherichia coli isolates being found resistant to ceftazidime and piperacillin. Most of the Pseudomonas aeruginosa isolates (75%) were found to be resistant to imipenem and aztreonam. All isolates had the ability to form biofilms. Overall, 56% of isolates were strong formers, and 29% were moderate biofilm formers. Strong biofilm formation was observed in most strains except for K. pneumoniae. Conclusion: The surveillance of susceptibility profiles and biofilm formation is important for determining their variable susceptibility patterns and aiding in the appropriate management of infections caused by these organisms.
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| APA | OYARDI O, HACIOGLU M, Yılmaz F, İNAN U, Birteksöz Tan A (2023). Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria. , 45 - 50. 10.26650/IstanbulJPharm.2023.1156339 |
| Chicago | OYARDI OZLEM,HACIOGLU MAYRAM,Yılmaz Fatıma nur,İNAN Urdoğan Neşe,Birteksöz Tan Ayşe Seher Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria. (2023): 45 - 50. 10.26650/IstanbulJPharm.2023.1156339 |
| MLA | OYARDI OZLEM,HACIOGLU MAYRAM,Yılmaz Fatıma nur,İNAN Urdoğan Neşe,Birteksöz Tan Ayşe Seher Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria. , 2023, ss.45 - 50. 10.26650/IstanbulJPharm.2023.1156339 |
| AMA | OYARDI O,HACIOGLU M,Yılmaz F,İNAN U,Birteksöz Tan A Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria. . 2023; 45 - 50. 10.26650/IstanbulJPharm.2023.1156339 |
| Vancouver | OYARDI O,HACIOGLU M,Yılmaz F,İNAN U,Birteksöz Tan A Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria. . 2023; 45 - 50. 10.26650/IstanbulJPharm.2023.1156339 |
| IEEE | OYARDI O,HACIOGLU M,Yılmaz F,İNAN U,Birteksöz Tan A "Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria." , ss.45 - 50, 2023. 10.26650/IstanbulJPharm.2023.1156339 |
| ISNAD | OYARDI, OZLEM vd. "Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria". (2023), 45-50. https://doi.org/10.26650/IstanbulJPharm.2023.1156339 |
| APA | OYARDI O, HACIOGLU M, Yılmaz F, İNAN U, Birteksöz Tan A (2023). Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria. Istanbul Journal of Pharmacy, 53(1), 45 - 50. 10.26650/IstanbulJPharm.2023.1156339 |
| Chicago | OYARDI OZLEM,HACIOGLU MAYRAM,Yılmaz Fatıma nur,İNAN Urdoğan Neşe,Birteksöz Tan Ayşe Seher Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria. Istanbul Journal of Pharmacy 53, no.1 (2023): 45 - 50. 10.26650/IstanbulJPharm.2023.1156339 |
| MLA | OYARDI OZLEM,HACIOGLU MAYRAM,Yılmaz Fatıma nur,İNAN Urdoğan Neşe,Birteksöz Tan Ayşe Seher Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria. Istanbul Journal of Pharmacy, vol.53, no.1, 2023, ss.45 - 50. 10.26650/IstanbulJPharm.2023.1156339 |
| AMA | OYARDI O,HACIOGLU M,Yılmaz F,İNAN U,Birteksöz Tan A Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria. Istanbul Journal of Pharmacy. 2023; 53(1): 45 - 50. 10.26650/IstanbulJPharm.2023.1156339 |
| Vancouver | OYARDI O,HACIOGLU M,Yılmaz F,İNAN U,Birteksöz Tan A Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria. Istanbul Journal of Pharmacy. 2023; 53(1): 45 - 50. 10.26650/IstanbulJPharm.2023.1156339 |
| IEEE | OYARDI O,HACIOGLU M,Yılmaz F,İNAN U,Birteksöz Tan A "Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria." Istanbul Journal of Pharmacy, 53, ss.45 - 50, 2023. 10.26650/IstanbulJPharm.2023.1156339 |
| ISNAD | OYARDI, OZLEM vd. "Antibiotic susceptibility and biofilm formation of multi-drug resistant Gram-negative bacteria". Istanbul Journal of Pharmacy 53/1 (2023), 45-50. https://doi.org/10.26650/IstanbulJPharm.2023.1156339 |
