Objective: This study’s aim was to examine the inci- dence and survival of cancer in Sivas between 2013-2019. Material and Methods: In this retrospective cohort study, cancer registry data were analysed. Age, sex, treatment types, definitive pathological diag- nosis results, and survival status of patients were questioned. Results: A total of 7,946 people were diagnosed with cancer in the years exam- ined and 57.5% of the patients were male. Systemically the most com- mon type of cancer was digestive organ cancers (20.2%) (stomach, colon, anorectal, respectively). The most common cancers in male were prostate (16%), skin (14%), and bronchopulmonary (12%). The most common cancers in female were breast (22%), thyroid (16%), and skin (14%). The cancer incidence was between 1.4 per thousand and 2.3 per thousand. Life expectancy was shorter (p<0.001), and the mortality risk was 1.6 times higher in male. The risk of cancer mortality increased with increasing age. Respiratory system and intrathoracic organ can- cers were the cancers that caused the death and shortened the life span most (p<0.001). Conclusion: It was found that the cancer incidence tended to increase, and that the cancer mortality was higher in male and respiratory system organ cancers. It is important to keep detailed records (especially by including the stage and treatment protocols) in the follow-up of cancer cases.