Yıl: 2023 Cilt: 31 Sayı: 2 Sayfa Aralığı: 75 - 81 Metin Dili: İngilizce DOI: 10.5152/FNJN.2023.22156 İndeks Tarihi: 27-07-2023

Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups

Öz:
AIM: This study aims to evaluate the impact of peripheral neuropathy symptoms throughout with monthly follow-ups during 4 months of paclitaxel treatment. METHODS: This prospective cross-sectional study was conducted with 79 patients. The study population consisted of female patients with breast cancer between August 2018 and January 2019. ‘’Chemotherapy-Induced Peripheral Neuropathy Assessment Tool’’ and ‘’EORTC C30 Cancer Quality of Life Questionnaire’’ were applied with four follow-ups. The study was undertaken in accordance with the STROBE checklist for cross- sectional studies. RESULTS: The Chemotherapy-Induced Peripheral Neuropathy Assessment Tool except for the general activity subdimension were statistically significant in the ratings of second, compared to first; third compared to first and second; fourth compared to first, second, and third follow-up periods. The overall mean of the EORTC C30 Cancer Quality of Life Questionnaire, functioning, symptom, and global health status were statistically significant in the evaluations of second, compared with first; third compared with first and second; fourth compared with first, second, and third follow-up periods. CONCLUSION: Findings from this study suggest that the increase in neuropathy symptoms during cures negatively affects the quality of life.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • Argyriou, A. A., Kyritsis, A. P., Makatsoris, T., & Kalofonos, H. P. (2014). Chemotherapy-induced peripheral neuropathy in adults: A comprehen- sive update of the literature. Cancer Management and Research, 6, 135–147. [CrossRef]
  • Bao, T., Basal, C., Seluzicki, C., Li, S. Q., Seidman, A. D., & Mao, J. J. (2016). Long-term chemotherapy-induced peripheral neuropathy among breast cancer survivors: Prevalence, risk factors, and fall risk. Breast Cancer Research and Treatment, 159(2), 327–333. [CrossRef]
  • Colvin, L. A. (2019). Chemotherapy-induced peripheral neuropathy (CIPN): Where are we now? Pain, 160(1), 1–10.
  • Dhawan, S., Andrews, R., Kumar, L., Wadhwa, S., & Shukla, G. (2020). A randomized controlled trial to assess the effectiveness of muscle strengthening and balancing exercises on chemotherapy-induced peripheral neuropathic pain and quality of life among cancer patients. Cancer Nursing, 43(4), 269–280. [CrossRef]
  • Diaz, M., & Schiff, D. (2020). Neurological complications of chemo- therapy. In Central nervous system metastases (pp. 329–340). Springer. Dorsey, S. G., Kleckner, I. R., Barton, D., Mustian, K., O’Mara, A., St Germain, D., Cavaletti, G., Danhauer, S. C., Hershman, D. L., Hohmann, A. G., Hoke, A., Hopkins, J. O., Kelly, K. P., Loprinzi, C. L., McLeod, H. L., Mohile, S., Paice, J., Rowland, J. H., Salvemini, D., Segal, R. A., et al.
  • (2019). The National Cancer Institute clinical trials planning meeting for prevention and treatment of chemotherapy-induced peripheral neuropathy. Journal of the National Cancer Institute, 111(6), 531–537. [CrossRef]
  • Duregon, F., Vendramin, B., Bullo, V., Gobbo, S., Cugusi, L., Di Blasio, A., Neunhaeuserer, D., Zaccaria, M., Bergamin, M., & Ermolao, A. (2018). Effects of exercise on cancer patients suffering chemotherapy-induced peripheral neuropathy undergoing treatment: A systematic review. Critical Reviews in Oncology/Hematology, 121, 90–100. [CrossRef]
  • Eckhoff, L., Knoop, A. S., Jensen, M. B., & Ewertz, M. (2015). Persis- tence of docetaxel-induced neuropathy and impact on quality of life among breast cancer survivors. European Journal of Cancer, 51(3), 292–300. [CrossRef]
  • Ewertz, M., Qvortrup, C., & Eckhoff, L. (2015). Chemotherapy- induced peripheral neuropathy in patients treated with taxanes and platinum derivatives. Acta Oncologica, 54(5), 587–591. [CrossRef]
  • Galantino, M. L., Tiger, R., Brooks, J., Jang, S., & Wilson, K. (2019). Impact of somatic yoga and meditation on fall risk, function, and quality of life for chemotherapy-induced peripheral neuropathy syndrome in cancer survivors. Integrative Cancer Therapies, 18, 1534735419850627. [CrossRef]
  • Greenlee, H., Hershman, D. L., Shi, Z., Kwan, M. L., Ergas, I. J., Roh, J. M., & Kushi, L. H. (2017). BMI, lifestyle factors and taxane-induced neu- ropathy in breast cancer patients: The pathways study. Journal of the National Cancer Institute, 109(2). [CrossRef]
  • Guzelant, A., Goksel, T., Ozkok, S., Tasbakan, S., Aysan, T., & Bottom- ley, A. (2004). The European Organization for Research and Treatment of Cancer QLQ C30: An examination into the cultural validity and reli- ability of the Turkish version of the EORTC QLQ C30. European Journal of Cancer Care, 13(2), 135–144. [CrossRef]
  • Hershman, D. L., Lacchetti, C., Dworkin, R. H., Lavoie Smith, E. M., Bleeker, J., Cavaletti, G., Chauhan, C., Gavin, P., Lavino, A., Lustberg, M. B., Paice, J., Schneider, B., Smith, M. L., Smith, T., Terstriep, S., Wagner- Johnston, N., Bak, K., Loprinzi, C. L., & American Society of Clinical Oncology (2014). Prevention and management of chemotherapy- induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline. Journal of Clini- cal Oncology, 32(18), 1941–1967. [CrossRef]
  • Jue, M. Y. (2022). Impact of cold therapy on paclitaxel-induced peripheral neuropathy and quality of life in patients with breast cancer. Number 1, 26(1), 93–99.
  • Kleckner, I. R., Kamen, C., Gewandter, J. S., Mohile, N. A., Heckler, C. E., Culakova, E., Fung, C., Janelsins, M. C., Asare, M., Lin, P. J., Reddy, P. S., Giguere, J., Berenberg, J., Kesler, S. R., & Mustian, K. M. (2018). Effects of exercise during chemotherapy on chemotherapy-induced peripheral neuropathy: A multicenter, randomized controlled trial. Supportive Care in Cancer, 26(4), 1019–1028. [CrossRef]
  • Kösemen, D., & Akın, S. (2016). Chemotherapy induced peripheral neurotoxicity and nursing ınterventions for management of peripheral neurotoxicity. Health and Society, 26, 26–36.
  • Kutlutürkan, S., Öztürk, E. S., Arıkan, F., Kahraman, B. B., Özcan, K., & Uçar, M. A. (2017). The psychometric properties of the Turkish ver- sion of the chemotherapy-induced peripheral neuropathy assessment tool (CIPNAT). European Journal of Oncology Nursing, 31, 84–89. [CrossRef]
  • Lichtman, S. M., Hurria, A., Cirrincione, C. T., Seidman, A. D., Winer, E., Hudis, C., Cohen, H. J., Muss, H. B., & Cancer and Leukemia Group B., Muss, H. B. (2012). Paclitaxel efficacy and toxicity in older women with metastatic breast cancer: Combined analysis of CALGB 9342 and 9840. Annals of Oncology, 23(3), 632–638. [CrossRef]
  • Loprinzi, C. L., Lacchetti, C., Bleeker, J., Cavaletti, G., Chauhan, C., Hertz, D. L., Kelley, M. R., Lavino, A., Lustberg, M. B., Paice, J. A., Schnei- der, B. P., Lavoie Smith, E. M., Smith, M. L., Smith, T. J., Wagner-John- ston, N., & Hershman, D. L. (2020). Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: ASCO guideline update. American Society of Clinical Ophthalmology.
  • Mols, F., Beijers, T., Lemmens, V., van den Hurk, C. J., Vreugdenhil, G., & van de Poll-Franse, L. V. (2013). Chemotherapy-induced neuropathy and its association with quality of life among 2-to 11-year colorectal cancer survivors: Results from the population-based PROFILES registry. Journal of Clinical Oncology, 31(21), 2699–2707. [CrossRef]
  • Obaid, A., El-Aqoul, A., Alafafsheh, A., Abu-Khudair, H., Saleh, M., & Kuliab, A. (2020). Validation of the Arabic version of the chemotherapy- induced peripheral neuropathy assessment tool. Pain Management Nursing, 21(6), 587–593. [CrossRef]
  • Oh, P. J., & Cho, J. R. (2020). Changes in fatigue, psychological dis- tress, and quality of life after chemotherapy in women with breast can- cer: A prospective study. Cancer Nursing, 43(1), E54–E60. [CrossRef]
  • Önsüz, Ü., & Can, G. (2020). The quality of life of cancer patients who have and not apply intervention in the management of taxane induced peripheral neuropathy. Izmir Democracy University Health Sciences Journal, 2, 114–134.
  • Park, J. H., Bae, S. H., Jung, Y. S., & Kim, K. S. (2012). Quality of life and symptom experience in breast cancer survivors after participating in a psychoeducational support program: A pilot study. Cancer Nursing, 35(1), E34–E41. [CrossRef]
  • Patel, R., Lyne-Ethier, J., Brogly, S., Griffiths, R., & Hendry, J. M. (2022). The effect of trastuzumab on taxane-induced peripheral neuropathy in women with breast cancer: A population-based cohort study.
  • Seretny, M., Currie, G. L., Sena, E. S., Ramnarine, S., Grant, R., MacLeod, M. R., Colvin, L. A., & Fallon, M., & Fallon, M. (2014). Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: A sys- tematic review and meta-analysis. Pain, 155(12), 2461–2470. [CrossRef]
  • Tofthagen, C. S., McMillan, S. C., & Kip, K. E. (2011). Development and psychometric evaluation of the chemotherapy-induced peripheral neu- ropathy assessment tool. Cancer Nursing, 34(4), E10–E20. [CrossRef]
  • Tofthagen, C., Overcash, J., & Kip, K. (2012). Falls in persons with chemotherapy-induced peripheral neuropathy. Supportive Care in Can- cer, 20(3), 583–589. [CrossRef]
  • Uçar, M. A. (2017). Chemotherapy-induced chronic peripheral neu- ropathy and its effect on quality of life [Master’s Thesis]. Akdeniz University.
  • Van Eijk, M., Vermunt, M. A. C., van Werkhoven, E., Wilthagen, E. A., Huitema, A. D. R., & Beijnen, J. H. (2022). The influence of docetaxel schedule on treatment tolerability and efficacy in patients with meta- static breast cancer: A systematic review and meta-analysis of rand- omized controlled trials. BMC Cancer, 22(1), 104. [CrossRef]
  • Winters-Stone, K. M., Hilton, C., Luoh, S. W., Jacobs, P., Faithfull, S., & Horak, F. B. (2016). Comparison of physical function and falls among women with persistent symptoms of chemotherapy-induced peripheral neuropathy. Journal of Clinical Oncology, 34(3_suppl), 130–130. [CrossRef]
  • Zimmer, P., Trebing, S., Timmers-Trebing, U., Schenk, A., Paust, R., Bloch, W., Rudolph, R., Streckmann, F., & Baumann, F. T., Streckmann, F., & Baumann, F. T. (2018). Eight-week, multimodal exercise counter- acts a progress of chemotherapy-induced peripheral neuropathy and improves balance and strength in metastasized colorectal cancer patients: A randomized controlled trial. Supportive Care in Cancer, 26(2), 615–624. [CrossRef]
APA KURT B, SİPAHİ KARSLI Z, oksuzoglu b, ÖZTÜRK E, DEMİRÖRS N, Dag O (2023). Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups. , 75 - 81. 10.5152/FNJN.2023.22156
Chicago KURT BERNA,SİPAHİ KARSLI ZEYNEP,oksuzoglu berna,ÖZTÜRK EMİNE,DEMİRÖRS NESLİHAN,Dag Osman Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups. (2023): 75 - 81. 10.5152/FNJN.2023.22156
MLA KURT BERNA,SİPAHİ KARSLI ZEYNEP,oksuzoglu berna,ÖZTÜRK EMİNE,DEMİRÖRS NESLİHAN,Dag Osman Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups. , 2023, ss.75 - 81. 10.5152/FNJN.2023.22156
AMA KURT B,SİPAHİ KARSLI Z,oksuzoglu b,ÖZTÜRK E,DEMİRÖRS N,Dag O Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups. . 2023; 75 - 81. 10.5152/FNJN.2023.22156
Vancouver KURT B,SİPAHİ KARSLI Z,oksuzoglu b,ÖZTÜRK E,DEMİRÖRS N,Dag O Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups. . 2023; 75 - 81. 10.5152/FNJN.2023.22156
IEEE KURT B,SİPAHİ KARSLI Z,oksuzoglu b,ÖZTÜRK E,DEMİRÖRS N,Dag O "Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups." , ss.75 - 81, 2023. 10.5152/FNJN.2023.22156
ISNAD KURT, BERNA vd. "Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups". (2023), 75-81. https://doi.org/10.5152/FNJN.2023.22156
APA KURT B, SİPAHİ KARSLI Z, oksuzoglu b, ÖZTÜRK E, DEMİRÖRS N, Dag O (2023). Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups. Florence Nightingale journal of nursing (Online), 31(2), 75 - 81. 10.5152/FNJN.2023.22156
Chicago KURT BERNA,SİPAHİ KARSLI ZEYNEP,oksuzoglu berna,ÖZTÜRK EMİNE,DEMİRÖRS NESLİHAN,Dag Osman Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups. Florence Nightingale journal of nursing (Online) 31, no.2 (2023): 75 - 81. 10.5152/FNJN.2023.22156
MLA KURT BERNA,SİPAHİ KARSLI ZEYNEP,oksuzoglu berna,ÖZTÜRK EMİNE,DEMİRÖRS NESLİHAN,Dag Osman Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups. Florence Nightingale journal of nursing (Online), vol.31, no.2, 2023, ss.75 - 81. 10.5152/FNJN.2023.22156
AMA KURT B,SİPAHİ KARSLI Z,oksuzoglu b,ÖZTÜRK E,DEMİRÖRS N,Dag O Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups. Florence Nightingale journal of nursing (Online). 2023; 31(2): 75 - 81. 10.5152/FNJN.2023.22156
Vancouver KURT B,SİPAHİ KARSLI Z,oksuzoglu b,ÖZTÜRK E,DEMİRÖRS N,Dag O Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups. Florence Nightingale journal of nursing (Online). 2023; 31(2): 75 - 81. 10.5152/FNJN.2023.22156
IEEE KURT B,SİPAHİ KARSLI Z,oksuzoglu b,ÖZTÜRK E,DEMİRÖRS N,Dag O "Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups." Florence Nightingale journal of nursing (Online), 31, ss.75 - 81, 2023. 10.5152/FNJN.2023.22156
ISNAD KURT, BERNA vd. "Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups". Florence Nightingale journal of nursing (Online) 31/2 (2023), 75-81. https://doi.org/10.5152/FNJN.2023.22156