According to Baudrillard's simulation theory, with the transition from the production order to the consumption order or from the political economy to the indicative political economy, the human being, like everything else, has turned into a sign in the simulation universe, in other words, the simulacrum. The transformation of human into simulacrum has only occurred naturally over time, in harmony with the system and as a result of the hegemony of it. The transhumanist process emerged and developed in the simulation universe, but it was aimed to create a new type of physical and biological human being by intervening in human nature in a planned and purposeful way. Transhumanism aims at a posthuman or humanoid understanding in which a new kind of human will emerge. In this context, in our study, it shows that the human being can’t be considered as a simulacrum in line with the interests of the system in which the human lives unconsciously or without being aware of the transformation as he consciously transforms himself physically and biologically. It explains that the human being has lost her naturalness or become artificial and entered the posthuman process. In short, our study shows with a qualitative approach and document analysis method that the state of being simulacrum, which Baudrillard expressed in his simulation theory, has ended, and that human has evolved into another artificial being on the basis of transhumanist thought consciously and in a planned way.