Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.

DEMİRKOZ, Ayşe Aslı Barla; KOLAK, UFUK; Öztürk, Mehmet; Topcu, Gulacti; ULUBELEN, Ayhan; KUŞMAN, Tuğba

Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.

Gülaçtı TOPÇU, (Bezmialem Vakfı Üniversitesi, Eczacılık Fakültesi, Farmakognozi ve Bitki Kimyası Bölümü, İstanbul, Türkiye)

Mehmet ÖZTÜRK, (Muğla Üniversitesi, Fen Fakültesi, Kimya Bölümü, Muğla, Türkiye)

Tuğba KUŞMAN, (Bezmialem Vakfı Üniversitesi, Eczacılık Fakültesi, Farmakognozi ve Bitki Kimyası Bölümü, İstanbul, Türkiye)

Ayşe Aslı Barla DEMİRKOZ, (Boş)

Ufuk KOLAK, (İstanbul Üniversitesi, Eczacılık Fakültesi, Genel Kimya Bilim Dalı, İstanbul, Türkiye)

Ayhan ULUBELEN (İstanbul Üniversitesi, Eczacılık Fakültesi, Genel Kimya Bilim Dalı, İstanbul, Türkiye)

Turkish Journal of Chemistry

1 0

Yıl: 2013 Cilt: 37 Sayı: 4 Sayfa Aralığı: 619 - 632 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.

Öz:

The hexane and dichloromethane extracts, obtained by re-extraction of the methanol extract of Salvia fruticosa Mill., a orded 7 diterpenoids (carnosol, carnosic acid, carnosic acid 12-methyl ether, rosmadial, isorosmanol, ferruginol, and manool), 4 triterpenoids ( -amyryltetracosanoate, oleanolic acid, ursolic acid, and erythrodiol), a steroid (3-acetylsitosterol), and aavone (salvigenin). The galls (apples) of the collected plant were separately extracted with hexane to a ord fatty acids composed mainly of oleic acid (29%), palmitoleic acid (29%), and stearic acid (23.20%), which exhibited high anticholinesterase activity, particularly against BChE. The essential oil, obtained from the aerial parts of the plant, exhibited high AChE inhibitory activity, consisting of mainly 1,8-cineol (58.89%). The antioxidant activity according to 6 complementary tests and anticholinesterase potential of the methanol extracts and triterpenoids $alpha$-amyryltetracosanoate, oleanolic acid, ursolic acid, and sitosterol acetate were also investigated, and methanol extract exhibited the highest antioxidant and anticholinesterase activity, surpassing the other tested extracts and pure compounds.

Anahtar Kelime:

Konular: Mühendislik, Kimya

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Topcu G, Öztürk M, KUŞMAN T, DEMİRKOZ A, KOLAK U, ULUBELEN A (2013). Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.. , 619 - 632.
Chicago	Topcu Gulacti,Öztürk Mehmet,KUŞMAN Tuğba,DEMİRKOZ Ayşe Aslı Barla,KOLAK UFUK,ULUBELEN Ayhan Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.. (2013): 619 - 632.
MLA	Topcu Gulacti,Öztürk Mehmet,KUŞMAN Tuğba,DEMİRKOZ Ayşe Aslı Barla,KOLAK UFUK,ULUBELEN Ayhan Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.. , 2013, ss.619 - 632.
AMA	Topcu G,Öztürk M,KUŞMAN T,DEMİRKOZ A,KOLAK U,ULUBELEN A Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.. . 2013; 619 - 632.
Vancouver	Topcu G,Öztürk M,KUŞMAN T,DEMİRKOZ A,KOLAK U,ULUBELEN A Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.. . 2013; 619 - 632.
IEEE	Topcu G,Öztürk M,KUŞMAN T,DEMİRKOZ A,KOLAK U,ULUBELEN A "Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.." , ss.619 - 632, 2013.
ISNAD	Topcu, Gulacti vd. "Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.". (2013), 619-632.

APA	Topcu G, Öztürk M, KUŞMAN T, DEMİRKOZ A, KOLAK U, ULUBELEN A (2013). Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.. Turkish Journal of Chemistry, 37(4), 619 - 632.
Chicago	Topcu Gulacti,Öztürk Mehmet,KUŞMAN Tuğba,DEMİRKOZ Ayşe Aslı Barla,KOLAK UFUK,ULUBELEN Ayhan Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.. Turkish Journal of Chemistry 37, no.4 (2013): 619 - 632.
MLA	Topcu Gulacti,Öztürk Mehmet,KUŞMAN Tuğba,DEMİRKOZ Ayşe Aslı Barla,KOLAK UFUK,ULUBELEN Ayhan Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.. Turkish Journal of Chemistry, vol.37, no.4, 2013, ss.619 - 632.
AMA	Topcu G,Öztürk M,KUŞMAN T,DEMİRKOZ A,KOLAK U,ULUBELEN A Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.. Turkish Journal of Chemistry. 2013; 37(4): 619 - 632.
Vancouver	Topcu G,Öztürk M,KUŞMAN T,DEMİRKOZ A,KOLAK U,ULUBELEN A Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.. Turkish Journal of Chemistry. 2013; 37(4): 619 - 632.
IEEE	Topcu G,Öztürk M,KUŞMAN T,DEMİRKOZ A,KOLAK U,ULUBELEN A "Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.." Turkish Journal of Chemistry, 37, ss.619 - 632, 2013.
ISNAD	Topcu, Gulacti vd. "Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.". Turkish Journal of Chemistry 37/4 (2013), 619-632.