Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study

Amaç: Atriyum fibrilasyonu (AF) klinik pratiğimizde en sık rastlanan ritm bozukluğu olup ülkemizde bu konuda yapılmış çok merkezli bir epidemiyolojik çalışma bulunmamaktadır. Bu çalışmanın amacı ülkemizde ilk kez yapılmış olan çok merkezli, ileriye dönük Atrial Fibrillation in Turkey: Epidemiologic Registry (AFTER) çalışmasının kayıtlarından yararlanarak AFye klinik yönden yaklaşımımızı değerlendirmektir. Çalışma planı: Ülkemizde nüfus dağılımı göz önünde bulundurularak 17 ayrı üçüncü basamak merkezden, elektrokardiyografisinde en az bir defa AF atağı tespit edilmiş olan ardışık 2242 hasta çalışmaya alındı. Acil polikliniğine başvuran ya da yatmakta olan hastalar çalışmadan dışlandı. Hastaların epidemiyolojik verileri ve uygulanan tedaviler değerlendirildi.Bulgular: Çalışma popülasyonunu oluşturan hastaların %60ı kadındı, hastaların ortalama yaşı 66.8±12.3 yıl olarak saptandı. Türk nüfusunda en sık görülen AF tipi non-valvular AF (%78) olup, AFli hastaların %81i ısrarcı-kalıcı AFli idi. AFye en sık eşlik eden komorbid durum hipertansiyon (%67) olarak bulundu. Hastaların %15.3ünde inme, geçici iskemik atak ve sistemik tromboemboli hikayesi mevcut iken kanama öyküsü hastaların %11.2sinde kaydedildi. Çalışma süresinde hastaların %50si warfarin, %53ü de aspirin kullanıyordu. Oral antikoagülan ilaç kullanan hastaların %41.3ünde etkin INR düzeyi saptandı. Oral antikoagülan ilaç kullanmamanın en sık nedeni (%69) hekim ihmali olarak saptandı.Sonuç: Bu veriler klinik pratiğimizde özellikle AFli hastaların antitrombotik tedavileri konusunda daha dikkatli olunması gerektiğini göstermektedir.

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Türkiye de atriyum fibrilasyonu epidemiyolojisi; çok merkezli AFTER çalışmasının ön sonuçları

Öz:

Objectives: Although atrial fibrillation (AF) is one of the most com- mon rhythm disorders observed in clinical practice, a multicenter epidemiological study has not been conducted in our country. This study aimed to assess our clinical approach to AF based upon the records of the first multicenter prospective Atrial Fibrillation in Tur- key: Epidemiologic Registry (AFTER) study. Study design: Taking into consideration the distribution of the population in our country, 2242 consecutive patients with at least one AF attack determined by electrocardiographic examination in 17 different tertiary health care centers were included in the study. Inpatients and patients that were admitted to emergency depart- ments were excluded from the study. Epidemiological data of the patients and the treatment administered were assessed. Results: The mean age of the patients was determined as 66.8±12.3 years with female patients representing 60% of the study popula- tion. While the most common AF type in the Turkish population was non-valvular AF (78%), persistent/permanent AF was determined in 81% of all patients. Hypertension (%67) was the most common co- morbidity in patients with AF. While a stroke or transient ischemic at- tack or history of systemic thromboembolism was detected in 15.3% of the patients, bleeding history was recorded in 11.2%. Also, 50% of the patients were on warfarin treatment and 53% were on aspi- rin treatment at the time of the study. The effective INR level was detected in 41.3% of the patients. The most frequent cause of not receiving anticoagulant therapy was physician neglect. Conclusion: These results demonstrate the necessity for improved quality of physician care of patients with AF, especially with regards to antithrombotic therapy.

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ERTAŞ F, Kaya H, KAYA Z, BULUR S, Köse N, GÜL M, KAHYA EREN N, ÇAĞLIYAN Ç, KÖROĞLU B, VATAN M, AÇAR G, Yüksel M, BILIK M, GEDİK S, Şimşek Z, AKIL M, YILMAZ R, OYLUMLU M, ARIBAŞ A, YILDIZ A, AYDIN M, YETER E, KANADAŞI M, ERGENE O, özhan h, ÜLGEN M (2013). Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study. , 99 - 104.
Chicago	ERTAŞ Faruk,Kaya Hasan,KAYA Zekeriya,BULUR Serkan,Köse Nuri,GÜL MEHMET,KAHYA EREN NİHAN,ÇAĞLIYAN Çağlar Emre,KÖROĞLU Bayram,VATAN MEHMET BÜLENT,AÇAR Göksel,Yüksel Murat,BILIK MEHMET ZIHNI,GEDİK Selçuk,Şimşek Ziya,AKIL Mehmet Ata,YILMAZ Rüstem,OYLUMLU Mustafa,ARIBAŞ Alpay,YILDIZ Abdulkadir,AYDIN MESUT,YETER Ekrem,KANADAŞI Mehmet,ERGENE Oktay,özhan hakan,ÜLGEN Mehmet Sıddık Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study. (2013): 99 - 104.
MLA	ERTAŞ Faruk,Kaya Hasan,KAYA Zekeriya,BULUR Serkan,Köse Nuri,GÜL MEHMET,KAHYA EREN NİHAN,ÇAĞLIYAN Çağlar Emre,KÖROĞLU Bayram,VATAN MEHMET BÜLENT,AÇAR Göksel,Yüksel Murat,BILIK MEHMET ZIHNI,GEDİK Selçuk,Şimşek Ziya,AKIL Mehmet Ata,YILMAZ Rüstem,OYLUMLU Mustafa,ARIBAŞ Alpay,YILDIZ Abdulkadir,AYDIN MESUT,YETER Ekrem,KANADAŞI Mehmet,ERGENE Oktay,özhan hakan,ÜLGEN Mehmet Sıddık Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study. , 2013, ss.99 - 104.
AMA	ERTAŞ F,Kaya H,KAYA Z,BULUR S,Köse N,GÜL M,KAHYA EREN N,ÇAĞLIYAN Ç,KÖROĞLU B,VATAN M,AÇAR G,Yüksel M,BILIK M,GEDİK S,Şimşek Z,AKIL M,YILMAZ R,OYLUMLU M,ARIBAŞ A,YILDIZ A,AYDIN M,YETER E,KANADAŞI M,ERGENE O,özhan h,ÜLGEN M Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study. . 2013; 99 - 104.
Vancouver	ERTAŞ F,Kaya H,KAYA Z,BULUR S,Köse N,GÜL M,KAHYA EREN N,ÇAĞLIYAN Ç,KÖROĞLU B,VATAN M,AÇAR G,Yüksel M,BILIK M,GEDİK S,Şimşek Z,AKIL M,YILMAZ R,OYLUMLU M,ARIBAŞ A,YILDIZ A,AYDIN M,YETER E,KANADAŞI M,ERGENE O,özhan h,ÜLGEN M Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study. . 2013; 99 - 104.
IEEE	ERTAŞ F,Kaya H,KAYA Z,BULUR S,Köse N,GÜL M,KAHYA EREN N,ÇAĞLIYAN Ç,KÖROĞLU B,VATAN M,AÇAR G,Yüksel M,BILIK M,GEDİK S,Şimşek Z,AKIL M,YILMAZ R,OYLUMLU M,ARIBAŞ A,YILDIZ A,AYDIN M,YETER E,KANADAŞI M,ERGENE O,özhan h,ÜLGEN M "Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study." , ss.99 - 104, 2013.
ISNAD	ERTAŞ, Faruk vd. "Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study". (2013), 99-104.

APA	ERTAŞ F, Kaya H, KAYA Z, BULUR S, Köse N, GÜL M, KAHYA EREN N, ÇAĞLIYAN Ç, KÖROĞLU B, VATAN M, AÇAR G, Yüksel M, BILIK M, GEDİK S, Şimşek Z, AKIL M, YILMAZ R, OYLUMLU M, ARIBAŞ A, YILDIZ A, AYDIN M, YETER E, KANADAŞI M, ERGENE O, özhan h, ÜLGEN M (2013). Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study. Türk Kardiyoloji Derneği Arşivi, 41(2), 99 - 104.
Chicago	ERTAŞ Faruk,Kaya Hasan,KAYA Zekeriya,BULUR Serkan,Köse Nuri,GÜL MEHMET,KAHYA EREN NİHAN,ÇAĞLIYAN Çağlar Emre,KÖROĞLU Bayram,VATAN MEHMET BÜLENT,AÇAR Göksel,Yüksel Murat,BILIK MEHMET ZIHNI,GEDİK Selçuk,Şimşek Ziya,AKIL Mehmet Ata,YILMAZ Rüstem,OYLUMLU Mustafa,ARIBAŞ Alpay,YILDIZ Abdulkadir,AYDIN MESUT,YETER Ekrem,KANADAŞI Mehmet,ERGENE Oktay,özhan hakan,ÜLGEN Mehmet Sıddık Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study. Türk Kardiyoloji Derneği Arşivi 41, no.2 (2013): 99 - 104.
MLA	ERTAŞ Faruk,Kaya Hasan,KAYA Zekeriya,BULUR Serkan,Köse Nuri,GÜL MEHMET,KAHYA EREN NİHAN,ÇAĞLIYAN Çağlar Emre,KÖROĞLU Bayram,VATAN MEHMET BÜLENT,AÇAR Göksel,Yüksel Murat,BILIK MEHMET ZIHNI,GEDİK Selçuk,Şimşek Ziya,AKIL Mehmet Ata,YILMAZ Rüstem,OYLUMLU Mustafa,ARIBAŞ Alpay,YILDIZ Abdulkadir,AYDIN MESUT,YETER Ekrem,KANADAŞI Mehmet,ERGENE Oktay,özhan hakan,ÜLGEN Mehmet Sıddık Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study. Türk Kardiyoloji Derneği Arşivi, vol.41, no.2, 2013, ss.99 - 104.
AMA	ERTAŞ F,Kaya H,KAYA Z,BULUR S,Köse N,GÜL M,KAHYA EREN N,ÇAĞLIYAN Ç,KÖROĞLU B,VATAN M,AÇAR G,Yüksel M,BILIK M,GEDİK S,Şimşek Z,AKIL M,YILMAZ R,OYLUMLU M,ARIBAŞ A,YILDIZ A,AYDIN M,YETER E,KANADAŞI M,ERGENE O,özhan h,ÜLGEN M Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study. Türk Kardiyoloji Derneği Arşivi. 2013; 41(2): 99 - 104.
Vancouver	ERTAŞ F,Kaya H,KAYA Z,BULUR S,Köse N,GÜL M,KAHYA EREN N,ÇAĞLIYAN Ç,KÖROĞLU B,VATAN M,AÇAR G,Yüksel M,BILIK M,GEDİK S,Şimşek Z,AKIL M,YILMAZ R,OYLUMLU M,ARIBAŞ A,YILDIZ A,AYDIN M,YETER E,KANADAŞI M,ERGENE O,özhan h,ÜLGEN M Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study. Türk Kardiyoloji Derneği Arşivi. 2013; 41(2): 99 - 104.
IEEE	ERTAŞ F,Kaya H,KAYA Z,BULUR S,Köse N,GÜL M,KAHYA EREN N,ÇAĞLIYAN Ç,KÖROĞLU B,VATAN M,AÇAR G,Yüksel M,BILIK M,GEDİK S,Şimşek Z,AKIL M,YILMAZ R,OYLUMLU M,ARIBAŞ A,YILDIZ A,AYDIN M,YETER E,KANADAŞI M,ERGENE O,özhan h,ÜLGEN M "Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study." Türk Kardiyoloji Derneği Arşivi, 41, ss.99 - 104, 2013.
ISNAD	ERTAŞ, Faruk vd. "Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study". Türk Kardiyoloji Derneği Arşivi 41/2 (2013), 99-104.