Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey

Mahmoud ABUDAYYAK, (İstanbul Üniversitesi, Eczacılık Fakültesi, Farmasötik Teknoloji Anabilim Dalı, İstanbul, Türkiye)
Ebru ÖZDEMİR NATH, (Yeni Yüzyıl Üniversitesi, Eczacılık Fakültesi, Farmasötik Botanik Anabilim Dalı, İstanbul, Türkiye)
Gül ÖZHAN (İstanbul Üniversitesi, Eczacılık Fakültesi, Farmasötik Teknoloji Anabilim Dalı, İstanbul, Türkiye)
Turkish Journal of Medical Sciences
102 1
Yıl: 2015 Cilt: 45 Sayı: 3 Sayfa Aralığı: 496 - 506 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey

Öz:
Background/aim: Sexual dysfunction is a serious problem worldwide. In Turkey, herbal products are used by some people suffering from sexual dysfunction. Despite their therapeutic advantages, some constituents of herbs are potentially toxic and pose health risks because they can be bought from the market without a prescription. Therefore, we aimed to determine the safety of herbs possessing aphrodisiac effects, chosen on the basis of their frequency of medicinal use and commercial importance in Turkey. Materials and methods: Ten herbs (Anethum graveolens, Carthamus tinctorius, Citrus aurantium, Cocos nucifera, Glycyrrhiza glabra, Melissa officinalis, Nigella arvensis, Pinus pinea, Prunus mahaleb, and Zingiber officinale) were extracted with water, methanol, and chloroform. The cyto- and genotoxic potentials of the extracts were assessed using an MTT test on a rat kidney cell line and an Ames assay in Salmonella typhimurium strains, respectively. Results: In the cytotoxic evaluation, IC50 values were 1.51-31.4 mg/mL for the methanol and chloroform extracts, while the water extracts were not cytotoxic. In the genotoxic evaluation, it was revealed that the water extracts had more mutagenic activity than the chloroform and methanol extracts. Water extract of M. officinalis was shown to have the most genotoxic activities to TA100 (±S9) and TA98 (-S9). Conclusion: These results might be useful in determining the toxic effects of herbs and lead to precautions being taken in regards to their consumption.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Abudayyak M, ÖZDEMİR NATH E, ÖZHAN G (2015). Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey. , 496 - 506.
Chicago Abudayyak Mahmoud,ÖZDEMİR NATH Ebru,ÖZHAN GÜL Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey. (2015): 496 - 506.
MLA Abudayyak Mahmoud,ÖZDEMİR NATH Ebru,ÖZHAN GÜL Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey. , 2015, ss.496 - 506.
AMA Abudayyak M,ÖZDEMİR NATH E,ÖZHAN G Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey. . 2015; 496 - 506.
Vancouver Abudayyak M,ÖZDEMİR NATH E,ÖZHAN G Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey. . 2015; 496 - 506.
IEEE Abudayyak M,ÖZDEMİR NATH E,ÖZHAN G "Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey." , ss.496 - 506, 2015.
ISNAD Abudayyak, Mahmoud vd. "Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey". (2015), 496-506.
APA Abudayyak M, ÖZDEMİR NATH E, ÖZHAN G (2015). Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey. Turkish Journal of Medical Sciences, 45(3), 496 - 506.
Chicago Abudayyak Mahmoud,ÖZDEMİR NATH Ebru,ÖZHAN GÜL Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey. Turkish Journal of Medical Sciences 45, no.3 (2015): 496 - 506.
MLA Abudayyak Mahmoud,ÖZDEMİR NATH Ebru,ÖZHAN GÜL Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey. Turkish Journal of Medical Sciences, vol.45, no.3, 2015, ss.496 - 506.
AMA Abudayyak M,ÖZDEMİR NATH E,ÖZHAN G Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey. Turkish Journal of Medical Sciences. 2015; 45(3): 496 - 506.
Vancouver Abudayyak M,ÖZDEMİR NATH E,ÖZHAN G Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey. Turkish Journal of Medical Sciences. 2015; 45(3): 496 - 506.
IEEE Abudayyak M,ÖZDEMİR NATH E,ÖZHAN G "Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey." Turkish Journal of Medical Sciences, 45, ss.496 - 506, 2015.
ISNAD Abudayyak, Mahmoud vd. "Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey". Turkish Journal of Medical Sciences 45/3 (2015), 496-506.
Sayfa Oluşturulma Tarihi
22-04-2024 21:10

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