Health-related quality of life in laryngeal cancer patients

Pinarbasli, Mehmet Ozgur; KEÇİK, Cem; CİNGİ, Cemal; GÜRBÜZ, Melek Kezban; INCESULU, S. ARMAGAN; KAYA, Ercan; Çaklı, Hamdi; ÖZÜDOĞRU, Erkan Niyazi

Health-related quality of life in laryngeal cancer patients

Ercan KAYA, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları Anabilim Dalı, Eskişehir, Türkiye)

Cemal CİNGİ, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları Anabilim Dalı, Eskişehir, Türkiye)

MEHMET ÖZGÜR PINARBAŞLI, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları Anabilim Dalı, Eskişehir, Türkiye)

Melek Kezban GÜRBÜZ, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları Anabilim Dalı, Eskişehir, Türkiye)

Hamdi ÇAKLI, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları Anabilim Dalı, Eskişehir, Türkiye)

Armağan İNCESULU, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları Anabilim Dalı, Eskişehir, Türkiye)

Erkan Niyazi ÖZÜDOĞRU, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları Anabilim Dalı, Eskişehir, Türkiye)

Cem KEÇİK (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları Anabilim Dalı, Eskişehir, Türkiye)

Journal of Medical Updates

2 0

Yıl: 2014 Cilt: 4 Sayı: 1 Sayfa Aralığı: 29 - 36 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Health-related quality of life in laryngeal cancer patients

Öz:

Amaç: Bu çalışmanın amacı larenks kanserli hastalarda sağlıkla ilgili yaşam kalitesini genel ve baş ve boyun kanserine özel anketler kullanılarak karşılaştırmaktır.Yöntem: Ocak 2003 ve Ocak 2006 tarihleri arasında larenks kanseri tanısı alan 52 hasta çalışmaya dâhil edildi. Hastalardan EORTC QLQ-C30 ve EORTC QLQ-H&N35 anket formları doldurmaları istendi. Bu anketler tedavi öncesi ve tedavi sonrası 1.,. 2. 3., 6., ve 12. aylarda dolduruldu.Bulgular: Takiplerinin 12. ayına dek herhangi bir tümör nüksü gözlenmeyen ve cerrahi tedavi veya kemoterapi alan hastalar değerlendirildi. QLQ-C30 anket skorları, ishal değişkeni dışındaki tüm değişkenler açısından istatistiksel olarak anlamlı bulundu. QLQ-H&N35 anket skorları, ağzını açma, besin takviyesi alımı ve besleme tüpü kullanımı dışındaki tüm değişkenler açısından istatistiksel olarak anlamlı bulundu.Sonuç: Fonksiyonel cerrahi geçirmiş hastaların yaşam kalitesinin daha tatmin edici olması nedeniyle, onkolojik prensiplerin izin verdiği ölçüde fonksiyonel cerrahi tercih edilmelidir.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Larenks kanserli hastalarda sağlıkta yaşam kalitesi

Öz:

Objective: To compare health-related quality of life (QOL) in laryngeal cancer patients using generic and head and neck cancer-specific questionnaires.Methods: A total of 52 patients, who were diagnosed as laryngeal cancer between January 2003 and January 2006, were included in the study. The patients were requested to fill up EORTC QLQ-C30 and EORTC QLQ-H&N35 questionnaire forms. These questionnaires were responded by the patients before treatment and at 1st, 2nd, 3rd, 6th and 12th months of the treatment.Results: Patients who received surgical therapy or chemotherapy for laryngeal cancer without any tumor recurrence up to 12th month of the treatment were evaluated. Changes in the mean values of all variables other than the changes in the mean score of diarrhea variable of QLQ-C30 questionnaire were found to be statistically significant. The questionnaire scores of QLQ-H&N35 were found to be statistically significant in terms of all variables except opening mouth, intake of nutritional supplements and use of feeding tube.Conclusion: Conclusion: Since quality of life of the patients who had undergone functional surgery is more satisfactory, functional surgery should be preferred to the extent permitted by oncological principles.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. Fung K, Lyden TH, Lee J , et al. Voice and swallowing outcomes of an organ-preservation trial for advanced laryngeal cancer. Int J Radiat Oncol Biol Physiol 2005;63:1395-9.
2. Aaronson NK, Bullinger M, Ahmedzai S. A modular approach to quality-of-life assessment in cancer clinical trials. Recent Results Cancer Res 1988;111:231-49.
3. Breitbart W, Holland J . Psychosocial aspects of head and neck cancer. Semin Oncol 1988;15:61-9.
4. Hanna E, Sherman A, Cash D, et al. Quality of life for patients following total laryngectomy vs chemoradiation for laryngeal preservation. Arch Otolaryngol Head Neck Surg 2004;130:875- 9.
5. QL Coordinator Quality of Life Unit, EORTC Data Center, Avenue E Mounier 83 - B11, 1200 Brussels, Belgium. Email: abo@eortc.be
6. Bjordal K, de Graeff A, Fayers PM, et al. A 12 country field study of the EORTC QLQ-C30 (version 3,0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients. EORTC Quality of Life Group. Eur J Cancer 2000; 36:1796-807.
7. Guzelant A, Goksel T, Ozkok S, Tasbakan S, Aysan T, Bottomley A. The European Organization for Research and Treatment of Cancer QLQ-C30: an examination into the cul- tural validity and reliability of the Turkish version of the EORTC QLQ-C30. Eur J Cancer Care (Engl) 2004;13:135-44.
8. Bjordal K, Ahlner EM, Tolleson et al. Development of a European Organization for research and Treatment of Cancer (EORTC) questionnaire module to be used in quality of life assessments in head and neck cancer. Acta Oncol 1994;33:879-85.
9. Bjordal K, Hammerlid E, Ahlner EM et al. Quality of life in head and neck patients: validation of the EORTC H&N35. J Clin Oncol 1999;17:1008-19.
10. Sherman AC, Simonton S, Adams DC, Vural E, Owens B, Hanna E. Assessing quality of life in patients with head and neck cancer: cross-validation of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Head and Neck module (QLQ-H&N35). Arch Otolaryngol Head Neck Surg 2000;126:459-67.
11. Bjordal K, de Graeff A, Fayers PM, et al. A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients. EORTC Quality of Life Group. Eur J Cancer 2000; 36:1796-807.
12. Nordgren M, Abendstein H, J annert M, et al. Health-related quality of life five years after diagnosis of laryngeal carcinoma. Int J Radiat Oncol Biol Phys 2003;56:1333-43.
13. Finizia C, Hammerlid E, Westin T, Lindstrom J . Quality of life and voice in patients with laryngeal carcinoma: a posttreatment comparison of laryngectomy (salvage surgery) versus radiothera- py. Laryngoscope 1998;108:1566-73.
14. Weinstein GS, El-Sawy MM, Ruiz C, et al. Laryngeal preservation with supracricoid partial laryngectomy results in improved quality of life when compared with total laryngectomy. Laryngoscope 2001;111:191-9.
15. Taş A, Yağız R, Karasalihoglu AR, Koten M, Adalı MK, Uzun C. Assessment of quality of life in patients with laryngeal cancer after surgical treatment. [Article in Turkish] Kulak Burun Bogaz Ihtis Derg 2004;12:84-90.
16. List MA, Ritter-Sterr CA, Baker TM, Colangelo LA, Matz G, Pauloski BR, Logemann JA. Longitudinal assessment of quality of life in laryngeal cancer patients. Head Neck 1996;18:1-10.
17. Hammerlid E, Mercke C, Sullivan M, Westin T. A prospective quality of life study of patients with laryngeal carcinoma by tumor stage and different radiation therapy schedules. Laryngoscope 1998;108:747-59.
18. Erdamar B, Süoğlu Y, Kıyak E, Sunay T, Katırcıoğlu S, Güven M, Akdağ K. Cerrahi tedavi uygulanan larenks kanserli hastaların uzun dönemde yaşam kalitelerinin değerlendirilmesi. Kulak Burun Bogaz Ihtis Derg 2001;8:219-25.
19. Hammerlid E, Silander E, Hornestam L, Sullivan M. Health- related quality of life three years after diagnosis of head and neck cancer-a longitudinal study. Head Neck 2001;23:113-25.
20. Stoeckli SJ , Guidicelli M, Schneider A, Huber A, Schmid S. Quality of life after treatment for early laryngeal carcinoma. Eur Arch Otorhinolaryngol 2001;258:96-9.
21. Hammerlid E, Bjordal K, Ahlner-Elmqvist M, et al. A prospec- tive study of quality of life in head and neck cancer patients. Part I: at diagnosis. Laryngoscope 2001;111(4 Pt 1):669-80.
22. DeSanto LW, Olsen KD, Perry WC, Rohe DE, Keith RL. Quality of life after surgical treatment of cancer of the larynx. Ann Otol Rhinol Laryngol 1995;104(10 Pt 1):763-9.
23. Muller R, Paneff J , Kollner V, Koch R. Quality of life of patients with laryngeal carcinoma: a post-treatment study. Eur Arch Otorhinolaryngol 2001;258:276-80.
24. de Graeff A, de Leeuw RJ , Ros WJ , et al. A prospective study on quality of life of laryngeal cancer patients treated with radiother- apy. Head Neck 1999;21:291-6.
25. Schneider A, Guidicelli M, Stockli SJ . Quality of life after treat- ment of laryngeal carcinoma: surgery versus radiotherapy. Schweiz Med Wochenschr Suppl 2000;116:31S-34S.
26. Kuntz AL, Weymuller EA Jr. Impact of neck dissection on qual- ty of life. Laryngoscope 1999;109:1334-8.
27. Terrell JE, Welsh DE, Bradford CR, et al. Pain, quality of life and spinal accessory nerve status after neck dissection. Laryngoscope 2000;110:620-6.
28. Braz DS, Ribas MM, Dedivitis RA, Nishimoto IN, Barros AP. Quality of life and depression in patients undergoing total and partial laryngectomy. Clinics (Sao Paulo) 2005;60:135-42.
29. Sewnaik A, Van Den Brink JL, Wieringa MH, Meeuwis CA, Kerrebijn J D. Surgery for recurrent laryngeal carcinoma after radiotherapy: partial laryngectomy or total laryngectomy for a better quality of life? Otolaryngol Head Neck Surg 2005;132:95- 8.

APA	KAYA E, CİNGİ C, Pinarbasli M, GÜRBÜZ M, Çaklı H, INCESULU S, ÖZÜDOĞRU E, KEÇİK C (2014). Health-related quality of life in laryngeal cancer patients. , 29 - 36.
Chicago	KAYA Ercan,CİNGİ Cemal,Pinarbasli Mehmet Ozgur,GÜRBÜZ Melek Kezban,Çaklı Hamdi,INCESULU S. ARMAGAN,ÖZÜDOĞRU Erkan Niyazi,KEÇİK Cem Health-related quality of life in laryngeal cancer patients. (2014): 29 - 36.
MLA	KAYA Ercan,CİNGİ Cemal,Pinarbasli Mehmet Ozgur,GÜRBÜZ Melek Kezban,Çaklı Hamdi,INCESULU S. ARMAGAN,ÖZÜDOĞRU Erkan Niyazi,KEÇİK Cem Health-related quality of life in laryngeal cancer patients. , 2014, ss.29 - 36.
AMA	KAYA E,CİNGİ C,Pinarbasli M,GÜRBÜZ M,Çaklı H,INCESULU S,ÖZÜDOĞRU E,KEÇİK C Health-related quality of life in laryngeal cancer patients. . 2014; 29 - 36.
Vancouver	KAYA E,CİNGİ C,Pinarbasli M,GÜRBÜZ M,Çaklı H,INCESULU S,ÖZÜDOĞRU E,KEÇİK C Health-related quality of life in laryngeal cancer patients. . 2014; 29 - 36.
IEEE	KAYA E,CİNGİ C,Pinarbasli M,GÜRBÜZ M,Çaklı H,INCESULU S,ÖZÜDOĞRU E,KEÇİK C "Health-related quality of life in laryngeal cancer patients." , ss.29 - 36, 2014.
ISNAD	KAYA, Ercan vd. "Health-related quality of life in laryngeal cancer patients". (2014), 29-36.

APA	KAYA E, CİNGİ C, Pinarbasli M, GÜRBÜZ M, Çaklı H, INCESULU S, ÖZÜDOĞRU E, KEÇİK C (2014). Health-related quality of life in laryngeal cancer patients. Journal of Medical Updates, 4(1), 29 - 36.
Chicago	KAYA Ercan,CİNGİ Cemal,Pinarbasli Mehmet Ozgur,GÜRBÜZ Melek Kezban,Çaklı Hamdi,INCESULU S. ARMAGAN,ÖZÜDOĞRU Erkan Niyazi,KEÇİK Cem Health-related quality of life in laryngeal cancer patients. Journal of Medical Updates 4, no.1 (2014): 29 - 36.
MLA	KAYA Ercan,CİNGİ Cemal,Pinarbasli Mehmet Ozgur,GÜRBÜZ Melek Kezban,Çaklı Hamdi,INCESULU S. ARMAGAN,ÖZÜDOĞRU Erkan Niyazi,KEÇİK Cem Health-related quality of life in laryngeal cancer patients. Journal of Medical Updates, vol.4, no.1, 2014, ss.29 - 36.
AMA	KAYA E,CİNGİ C,Pinarbasli M,GÜRBÜZ M,Çaklı H,INCESULU S,ÖZÜDOĞRU E,KEÇİK C Health-related quality of life in laryngeal cancer patients. Journal of Medical Updates. 2014; 4(1): 29 - 36.
Vancouver	KAYA E,CİNGİ C,Pinarbasli M,GÜRBÜZ M,Çaklı H,INCESULU S,ÖZÜDOĞRU E,KEÇİK C Health-related quality of life in laryngeal cancer patients. Journal of Medical Updates. 2014; 4(1): 29 - 36.
IEEE	KAYA E,CİNGİ C,Pinarbasli M,GÜRBÜZ M,Çaklı H,INCESULU S,ÖZÜDOĞRU E,KEÇİK C "Health-related quality of life in laryngeal cancer patients." Journal of Medical Updates, 4, ss.29 - 36, 2014.
ISNAD	KAYA, Ercan vd. "Health-related quality of life in laryngeal cancer patients". Journal of Medical Updates 4/1 (2014), 29-36.