Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri

TÜRKCAN, İrem; NALBANT, Asude Dilek

Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri

İrem TÜRKCAN, (Gazi Üniversitesi, Diş Hekimliği Fakültesi, Protetik Diş Tedavisi Anabilim Dalı, Ankara, Türkiye)

Asude Dilek NALBANT (Gazi Üniversitesi, Diş Hekimliği Fakültesi, Protetik Diş Tedavisi Anabilim Dalı, Ankara, Türkiye)

Acta Odontologica Turcica

6 2

Yıl: 2016 Cilt: 33 Sayı: 3 Sayfa Aralığı: 145 - 152 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri

Öz:

Diş hekimliği alanında farklı özellik ve içeriklere sahip çeşitli materyaller kullanılmaktadır. Bu materyaller, estetik ve fonksiyonel görevlerini yerine getirirken, ağız dokuları ve sıvılarıyla temas halindedir. Bu nedenle, kullanılan materyallerin fiziksel ve mekanik özelliklerinin yanı sıra, biyolojik olarak uyumlu olmaları aranılan en temel özelliktir. Biyomateryal, insan vücudu üzerine veya içerisine yerleştirilen ve biyolojik sistemle etkileşim halinde olan cansız materyaldir. Ağız içerisine yerleştirilen dental materyaller de biyomateryaller kapsamında yer almaktadır. Biyouyumluluk, belirli bir uygulamada bir materyalin, uygulandığı bölgede uygun bir konak cevabı oluşturabilme yeteneği olarak tanımlanmaktadır. Ağız içerisinde kullanılacak materyallerin oluşturacağı biyolojik cevabın önceden değerlendirilmesi gerekmektedir. Bu amaçla çeşitli test yöntemleri geliştirilmiş ve protokoller belirlenmiştir. Çoğunlukla hücre kültürlerinin kullanıldığı in vitro testler ile değerlendirilen materyaller, tatmin edici sonuçlar elde edildiği takdirde daha kapsamlı olan hayvan testlerine (in vivo) ve ardından son basamak olan klinik testlere tabi tutulmalıdır. Bu derlemenin amacı, biyouyumluluk test yöntemlerinin ve son yıllarda yapılan çalışmaların ışığında dental protetik materyallerin biyolojik uyumunun değerlendirilmesidir

Anahtar Kelime:

Konular: Diş Hekimliği

Biocompatibility of prosthodontic materials and test methods

Öz:

Various materials with different features and content are widely used in dentistry. While fulfilling their aesthetic and functional tasks, these materials are in contact with oral tissues and fluids. Therefore, besides physical and mechanical properties, biocompatibility also is a required property for these materials. Biomaterials are non-vital materials placed on or inside the human body, and inter-act with biological systems. Dental materials placed in the mouth are also considered as biomaterials. Biocompat-ibility is the ability of a material to perform with an ap-propriate host response when applied as intended. There are various test methods and protocols to evaluate the biological response generated by a dental material. Ini-tial in vitro tests resulting in satisfactory findings are fol-lowed by more comprehensive in vivo animal tests and clinical usage tests. The aim of this report is to review biocompatibility test methods and the biocompatibility of prosthodontic materials in the light of previous studies.

Anahtar Kelime:

Konular: Diş Hekimliği

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık

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APA	TÜRKCAN İ, NALBANT A (2016). Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri. , 145 - 152.
Chicago	TÜRKCAN İrem,NALBANT Asude Dilek Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri. (2016): 145 - 152.
MLA	TÜRKCAN İrem,NALBANT Asude Dilek Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri. , 2016, ss.145 - 152.
AMA	TÜRKCAN İ,NALBANT A Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri. . 2016; 145 - 152.
Vancouver	TÜRKCAN İ,NALBANT A Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri. . 2016; 145 - 152.
IEEE	TÜRKCAN İ,NALBANT A "Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri." , ss.145 - 152, 2016.
ISNAD	TÜRKCAN, İrem - NALBANT, Asude Dilek. "Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri". (2016), 145-152.

APA	TÜRKCAN İ, NALBANT A (2016). Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri. Acta Odontologica Turcica, 33(3), 145 - 152.
Chicago	TÜRKCAN İrem,NALBANT Asude Dilek Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri. Acta Odontologica Turcica 33, no.3 (2016): 145 - 152.
MLA	TÜRKCAN İrem,NALBANT Asude Dilek Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri. Acta Odontologica Turcica, vol.33, no.3, 2016, ss.145 - 152.
AMA	TÜRKCAN İ,NALBANT A Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri. Acta Odontologica Turcica. 2016; 33(3): 145 - 152.
Vancouver	TÜRKCAN İ,NALBANT A Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri. Acta Odontologica Turcica. 2016; 33(3): 145 - 152.
IEEE	TÜRKCAN İ,NALBANT A "Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri." Acta Odontologica Turcica, 33, ss.145 - 152, 2016.
ISNAD	TÜRKCAN, İrem - NALBANT, Asude Dilek. "Dental protetik materyallerin biyolojik uyumluluğu ve test yöntemleri". Acta Odontologica Turcica 33/3 (2016), 145-152.