Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq

KOŞAR, MÜBERRA; İLGÜN, Selen; Şeker Karatoprak, Gökçe

Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq

Gökçe Şeker KARATOPRAK, (Erciyes Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, Kayseri, Türkiye)

Selen İLGÜN, (Erciyes Üniversitesi, Eczacılık Fakültesi, Farmasötik Botanik Bölümü, Kayseri, Türkiye)

Müberra KOŞAR (Erciyes Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, Kayseri, Türkiye)

Turkish Journal of Pharmaceutical Sciences

12 2

Yıl: 2016 Cilt: 13 Sayı: 2 Sayfa Aralığı: 201 - 212 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq

Öz:

Salvia virgata Jacq.'ın toprak üstü kısımlarının metanol ve su ekstresinin fenolik içeriği ve antioksidan özellikleri belirlenmiştir. Her iki ekstrenin de toplam fenolik, toplam flavonoit ve flavonol içeriği, kalitatif-kantitatif kompozisyonları (YPSK ile), serbest radikal süpürücü aktiviteleri (DPPH? ve ABTS?+), demir(II) ile şelat oluşumu ve TBA yöntemi ile peroksidasyon seviyeleri incelenmiştir. IC50 değeri olarak verilen antioksidan aktiviteler butil hidroksianisol, butil hidroksitoluen, rozmarinik asit, askorbik asit ve gallik asit standartları ile karşılaştırılmıştır. Metanol ekstresi DPPH? radikalini süpürücü etkide aktif bulunurken, su ekstresi ABTS?+ radikalini süpürücü etkide aktif bulunmuştur. Metanol ektresinin fenolik bileşiminin daha zengin olduğu ve her iki ekstrede de rozmarinik asitin ana bileşen olduğu tespit edilmiştir.

Anahtar Kelime:

Konular: Farmakoloji ve Eczacılık

Salvia virgata Jacq.'ın Antioksidan Özellikleri ve Fenolik İçeriği

Öz:

Methanol and water extracts of Salvia virgata Jacq. aerial parts were examined for its phenolic contents and antioxidant activities. Both extracts were investigated for their total phenolic contents, total flavonoids and flavonols, qualitative-quantitative compositions (by HPLC-PDA analysis). Free radical scavenging activities (using DPPH? and ABTS?+), iron(II) chelation activity and also the peroxidation level was determined by TBA method. The antioxidant activity of extracts were given as IC50 values and compared with standards; butylated hydoxyanisole, butylated hydoxytoluene, rosmarinic acid, ascorbic acid, and gallic acid. Methanol extract was found to be active for DPPH? radical scavenging activity where as water extract was more active for ABTS?+ radical scavenging. The methanol extract enriched in phenolic compound and rosmarinic acid as the main component in both extracts has been identified.

Anahtar Kelime:

Konular: Farmakoloji ve Eczacılık

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Şeker Karatoprak G, İLGÜN S, KOŞAR M (2016). Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq. , 201 - 212.
Chicago	Şeker Karatoprak Gökçe,İLGÜN Selen,KOŞAR MÜBERRA Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq. (2016): 201 - 212.
MLA	Şeker Karatoprak Gökçe,İLGÜN Selen,KOŞAR MÜBERRA Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq. , 2016, ss.201 - 212.
AMA	Şeker Karatoprak G,İLGÜN S,KOŞAR M Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq. . 2016; 201 - 212.
Vancouver	Şeker Karatoprak G,İLGÜN S,KOŞAR M Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq. . 2016; 201 - 212.
IEEE	Şeker Karatoprak G,İLGÜN S,KOŞAR M "Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq." , ss.201 - 212, 2016.
ISNAD	Şeker Karatoprak, Gökçe vd. "Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq". (2016), 201-212.

APA	Şeker Karatoprak G, İLGÜN S, KOŞAR M (2016). Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq. Turkish Journal of Pharmaceutical Sciences, 13(2), 201 - 212.
Chicago	Şeker Karatoprak Gökçe,İLGÜN Selen,KOŞAR MÜBERRA Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq. Turkish Journal of Pharmaceutical Sciences 13, no.2 (2016): 201 - 212.
MLA	Şeker Karatoprak Gökçe,İLGÜN Selen,KOŞAR MÜBERRA Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq. Turkish Journal of Pharmaceutical Sciences, vol.13, no.2, 2016, ss.201 - 212.
AMA	Şeker Karatoprak G,İLGÜN S,KOŞAR M Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq. Turkish Journal of Pharmaceutical Sciences. 2016; 13(2): 201 - 212.
Vancouver	Şeker Karatoprak G,İLGÜN S,KOŞAR M Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq. Turkish Journal of Pharmaceutical Sciences. 2016; 13(2): 201 - 212.
IEEE	Şeker Karatoprak G,İLGÜN S,KOŞAR M "Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq." Turkish Journal of Pharmaceutical Sciences, 13, ss.201 - 212, 2016.
ISNAD	Şeker Karatoprak, Gökçe vd. "Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq". Turkish Journal of Pharmaceutical Sciences 13/2 (2016), 201-212.