A case of hyperkinetic movement disorder associated with LGI1 antibodies

YAPICI, Zuhal; OKAN, Mehmet; DURAN, Selcen; Taşkapılıoğlu, Özlem; Tuzun, Erdem; GİRİŞ, Murat; ERER ÖZBEK, Çiğdem Sevda

A case of hyperkinetic movement disorder associated with LGI1 antibodies

Çiğdem Sevda ERER ÖZBEK, (Division of Neurology, Institute of Neurological Sciences, Uludag University Faculty of Medicine, Bursa, Turkey)

Zuhal YAPICI, (Division of Child Neurology, Department of Neurology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey)

Erdem TÜZÜN, (Department of Neurosciences, Institute for Experimental Medical Research, Istanbul University, Istanbul, Turkey)

Murat GİRİŞ, (Department of Neurosciences, Institute for Experimental Medical Research, Istanbul University, Istanbul, Turkey)

Selcen DURAN, (Division of Neurology, Institute of Neurological Sciences, Uludag University Faculty of Medicine, Bursa, Turkey)

Özlem TAŞKAPILIOĞLU, (Division of Neurology, Institute of Neurological Sciences, Uludag University Faculty of Medicine, Bursa, Turkey)

Mehmet OKAN (Division of Neurology, Institute of Neurological Sciences, Uludag University Faculty of Medicine, Bursa, Turkey)

Turkish Journal of Pediatrics

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Yıl: 2015 Cilt: 57 Sayı: 5 Sayfa Aralığı: 514 - 517 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

A case of hyperkinetic movement disorder associated with LGI1 antibodies

Öz:

Erer-Özbek S, Yapıcı Z, Tüzün E, Giriş M, Duran S, Taşkapılıoğlu Ö, Okan M. A case of hyperkinetic movement disorder associated with LGI1 antibodies. Turk J Pediatr 2015; 57: 514-517.Encephalitis associated with leucine-rich glioma inactivated 1 (LGI1) antibodies is often encountered in elderly male patients and may infrequently present with isolated syndromes. A 6-year-old boy was admitted with acute onset severe oral and facial stereotypic and choreiform movements. On his neurologic examination, he had repetitive and rhythmic movements in orolingual muscles including tongue protrusion, limb chorea and minimal facial stereotypic movements. Anti-streptolysin O (ASO) titers were found severely elevated in several measurements. Well-characterized antibodies against ion channels and synapse proteins were negative whereas LGI1 antibody was positive in both serum and CSF. Marked clinical improvement was observed after immunotherapy. Here, we present the first pediatric case with LGI1 antibody associated hyperkinetic movement disorders and emphasize the importance of investigating neuronal autoantibodies in patients with isolated and treatment resistant movement disorders

Anahtar Kelime:

Konular: Pediatri

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık

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APA	ERER ÖZBEK Ç, YAPICI Z, Tuzun E, GİRİŞ M, DURAN S, Taşkapılıoğlu Ö, OKAN M (2015). A case of hyperkinetic movement disorder associated with LGI1 antibodies. , 514 - 517.
Chicago	ERER ÖZBEK Çiğdem Sevda,YAPICI Zuhal,Tuzun Erdem,GİRİŞ Murat,DURAN Selcen,Taşkapılıoğlu Özlem,OKAN Mehmet A case of hyperkinetic movement disorder associated with LGI1 antibodies. (2015): 514 - 517.
MLA	ERER ÖZBEK Çiğdem Sevda,YAPICI Zuhal,Tuzun Erdem,GİRİŞ Murat,DURAN Selcen,Taşkapılıoğlu Özlem,OKAN Mehmet A case of hyperkinetic movement disorder associated with LGI1 antibodies. , 2015, ss.514 - 517.
AMA	ERER ÖZBEK Ç,YAPICI Z,Tuzun E,GİRİŞ M,DURAN S,Taşkapılıoğlu Ö,OKAN M A case of hyperkinetic movement disorder associated with LGI1 antibodies. . 2015; 514 - 517.
Vancouver	ERER ÖZBEK Ç,YAPICI Z,Tuzun E,GİRİŞ M,DURAN S,Taşkapılıoğlu Ö,OKAN M A case of hyperkinetic movement disorder associated with LGI1 antibodies. . 2015; 514 - 517.
IEEE	ERER ÖZBEK Ç,YAPICI Z,Tuzun E,GİRİŞ M,DURAN S,Taşkapılıoğlu Ö,OKAN M "A case of hyperkinetic movement disorder associated with LGI1 antibodies." , ss.514 - 517, 2015.
ISNAD	ERER ÖZBEK, Çiğdem Sevda vd. "A case of hyperkinetic movement disorder associated with LGI1 antibodies". (2015), 514-517.

APA	ERER ÖZBEK Ç, YAPICI Z, Tuzun E, GİRİŞ M, DURAN S, Taşkapılıoğlu Ö, OKAN M (2015). A case of hyperkinetic movement disorder associated with LGI1 antibodies. Turkish Journal of Pediatrics, 57(5), 514 - 517.
Chicago	ERER ÖZBEK Çiğdem Sevda,YAPICI Zuhal,Tuzun Erdem,GİRİŞ Murat,DURAN Selcen,Taşkapılıoğlu Özlem,OKAN Mehmet A case of hyperkinetic movement disorder associated with LGI1 antibodies. Turkish Journal of Pediatrics 57, no.5 (2015): 514 - 517.
MLA	ERER ÖZBEK Çiğdem Sevda,YAPICI Zuhal,Tuzun Erdem,GİRİŞ Murat,DURAN Selcen,Taşkapılıoğlu Özlem,OKAN Mehmet A case of hyperkinetic movement disorder associated with LGI1 antibodies. Turkish Journal of Pediatrics, vol.57, no.5, 2015, ss.514 - 517.
AMA	ERER ÖZBEK Ç,YAPICI Z,Tuzun E,GİRİŞ M,DURAN S,Taşkapılıoğlu Ö,OKAN M A case of hyperkinetic movement disorder associated with LGI1 antibodies. Turkish Journal of Pediatrics. 2015; 57(5): 514 - 517.
Vancouver	ERER ÖZBEK Ç,YAPICI Z,Tuzun E,GİRİŞ M,DURAN S,Taşkapılıoğlu Ö,OKAN M A case of hyperkinetic movement disorder associated with LGI1 antibodies. Turkish Journal of Pediatrics. 2015; 57(5): 514 - 517.
IEEE	ERER ÖZBEK Ç,YAPICI Z,Tuzun E,GİRİŞ M,DURAN S,Taşkapılıoğlu Ö,OKAN M "A case of hyperkinetic movement disorder associated with LGI1 antibodies." Turkish Journal of Pediatrics, 57, ss.514 - 517, 2015.
ISNAD	ERER ÖZBEK, Çiğdem Sevda vd. "A case of hyperkinetic movement disorder associated with LGI1 antibodies". Turkish Journal of Pediatrics 57/5 (2015), 514-517.