Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability

karayurt, ozgul

Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability

Özgül KARAYURT (Vehbi Koç Foundation American Hosp)

Türkiye Klinikleri Hemşirelik Bilimleri Dergisi

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Yıl: 2016 Cilt: 8 Sayı: 4 Sayfa Aralığı: 325 - 334 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability

Öz:

ÖÖZZEETT AAmmaaçç:: Bu araştırmanın amacı Chisholm ve ark. (2005) tarafından geliştirilen İmmünsupre- sif Tedaviye Uyum Ölçeğini Türkçe'ye uyarlamak ve ölçeğin geçerlilik ve güvenirliliğini test etmek idi. GGeerreeçç vvee YYöönntteemmlleerr:: Bu kesitsel ve metodolojik çalışmaya Türk böbrek, karaciğer ve kalp nakil alıcıları dahil edilmiştir. Veriler "İmmünsupresif Tedaviye Uyum Ölçeği- Tr®" ve "Demo- grafik ve Klinik Özellikler Formu" kullanılarak toplanmıştır. Yapı geçerliği, açıklayıcı ve doğru- layıcı faktör analizi ile test edilmiştir. İmmünsupresif Tedaviye Uyum Ölçeği Tr®- ile serum immünsupresif tedavi düzeyleri arasındaki ilişki birleşen ve ayırt eden geçerliği ile; güvenilirlik ise Cronbach alfa ve madde analizi ile sınanmıştır. BBuullgguullaarr:: Çalışmaya 50 organ nakil alıcısı dahil edilmiştir. Yaklaşık Hataların Ortalama Karekökü=0,04, Standartlaştırılmış Ortalama Kare- kök=0,06, Karşılaştırmalı Uyum İndeksi)=0,94, İyilik Uyum İndeksi=0,92 olarak saptanmıştır. Kaiser-Meyer-Olkin değeri 1,62, Barlett testi=27,791 (p<0,001) iken, faktör yüklerinin 0,62 ile 0,93 arasında değiştiği tespit edilmiştir. Öz değeri 1'in üzerinde olan bir faktör elde edildiği, bir faktörün toplam varyansın %73,63'ünü açıkladığı saptanmıştır. Ölçek puanı ile hedeflenen im- münsupresif tedavi düzeyleri arasında incelenen birleşen geçerlik korelasyon katsayısı r=0,544 (p<0,001) olarak hesaplanmıştır. Cronbach alfa güvenilirlik katsayısı 0,65; madde-toplam kore- lasyon katsayısı 0,27 ile 0,69 arasında değişmektedir. SSoonnuuçç:: İmmünsupresif Tedaviye Uyum Öl- çeği-Tr®Türk organ nakil alıcılarında immünsupresif tedaviyi değerlendirmek için geçerli ve güvenilir bir araçtır.

Anahtar Kelime:

Konular: Diş Hekimliği

Öz:

The aim of this study was to adapt for Turkish and perform the validityand reliability studies of the Immunosuppressant Therapy Adherence Scale® (ITAS®) which isdeveloped by Chisholm et al. (2005). Material and Methods: This cross-sectional and methodologicalstudy included adult Turkish renal, liver, and heart transplant recipients. Data were collectedusing the Demographic and Clinical Characteristics Form and Turkish version ofImmunosuppressant Therapy Adherence Scale®. Construct validity was tested using exploratoryand confirmatory factor analyses. Convergent validity was tested by correlating ImmunosuppressantTherapy Adherence Scale-Tr® to serum immunosuppressant therapy concentrations. Reliabilitywas tested using Cronbach's alpha and item-to-total correlations. Results: Fifty transplantrecipients were included. Root mean squared error of approximation was 0.04, standardized rootmean square residual was 0.06, comparative fit index was 0.94, and goodness of fit index was0.92. Kaiser-Meyer-Olkin was 0.62 and Bartlett's test was 27.791 (p<0.001). Factor loads rangedfrom 0.62 to 0.93. Eugene value higher than 1 was obtained and explained 73.63% of total variance.Correlation between Immunosuppressant Therapy Adherence Scale-Tr® and serum immunosuppressanttherapy levels was 0.544 (p<0.001). Cronbach's alpha was 0.65; item-to-totalcorrelation coefficients ranged from 0.27 to 0.69. Conclusion: Immunosuppressant Therapy AdherenceScale-Tr® is a valid and reliable tool to evaluate immunosuppressant therapy adherencein Turkish organ transplant recipients.

Anahtar Kelime:

Konular: Diş Hekimliği

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. FlatteryMP, Dale C. Solid organ transplantation: the evaluation process. In:Ohler L, Cupples SA, eds. Core Curriculum for Transplant Nurses. 1st ed. Washington: Mosby Elseiver; 2008. p.1-25.
2. Lieber SR, Volk ML. Non-adherence and graft failure in adult liver transplant recipients. Dig Dis Sci 2013;58(3):824-34.
3. Gorevski E, Succop P, Sachdeva J, Cavanaugh TM, Volek P, Heaton P, et al. Is there an association between immunosuppressant therapy medication adherence and depression, quality of life and personality traits in the kidney and liver transplant population? Patient Prefer Adherence 2013;16(7):301-7.
4. Burra P, Germani G, Gnoato F, Lazzaro S, Russo FP, Cillo U, et al. Adherence in liver transplant recipients. Liver Transpl 2011; 17(7):760-70.
5. Denhaerynck K, Burkhalter F, Schäfer-Keller P, Steiger J, Bock A, De Geest S. Clinical consequences of non adherence to immunosuppressive medication in kidney transplant patients. Transpl Int 2009;22(4):441-6.
6. O'Carroll RE, McGregor LM, Swanson V, Masterton G, Hayes PC. Adherence to medication after liver transplantation in Scotland: a pilot study. Liver Transpl 2006;12(2):1862-8.
7. Chisholm MA. Issues of adherence to immunosuppressant therapy after solid-organ transplantation. Drugs 2002;62(4):567-75.
8. Chisholm MA, Lance CE, Williamson GM, Mulloy LL. Development and validation of the immunosuppressant therapy adherence instrument (ITAS). Patient Educ Couns 2005; 59(1):13-20.
9. Stilley CS, Dimartini AF, de Vera ME, Flynn WB, King J, Sereika S, et al. Individual and environmental correlates and predictors of early adherence and outcomes after liver transplantation. Prog Transplant 2010;20(1):58-66.
10. Cukor D, Newville H, Jindal R. Depression and immunosuppressive medication adherence in kidney transplant patients. Gen Hosp Psychiatry 2008;30(4):386-7.
11. Gheith OA, El-Saadany SA, Abuo Donia SA, Salem YM. Compliance of kidney transplant patients to the recommended lifestyle behaviours: single centre experience. Int J Nurs Pract 2008;14(5):398-407.
12. Gordon EJ, Prohaska TR, Gallant MP, Siminoff LA. Adherence to immunosuppression: a prospective diary study. Transplant Proc 2007;39(10):3081-5.
13. Fredericks EM, Magee JC, Opipari-Arrigan L, Shieck V, Well A, Lopez MJ. Adherence and health-related quality of life in adolescent liver transplant recipients. Pediatr Transplant 2008; 12(3):289-99.
14. Schäfer-Keller S, Steiger J, Bock A, Denhaerynck K, De Geest S. Diagnostic accuracy of measurement methods to assess non-adherence to immunosuppressive drugs in kidney transplant recipients. Am J Transplant 2008;8(3):616-26.
15. Chisholm MA, Lance CE, Mulloy LL. Patient factors associated with adherence to immunosuppressant therapy in renal transplant recipients. Am J Health-Syst Pharm 2005; 62(17):1775-81.
16. Abbott K. Medication compliance in transplantation. Am J Transplant 2007;7(12):2647- 9.
17. Wilks SE, Spivey CA, Chisholm-Burns MA. Psychometric re-evaluation of the immunosuppressant therapy adherence scale among solid-organ transplant recipients. J Eval Clin Pract 2010;16(1):64-8.
18. Tsapepas D, Langone A, Chan L, Wiland A, McCague K, Chisholm-Burns M. A longitudinal assessment of adherence with immunosuppressant therapy following kidney transplantation from the Mycophenolic Acid Obsevational Renal Transplant (MORE) study. Ann Transplant 2014;17(19):174-81.
19. Weng FL, Chandwani S, Kurtyka KM, Zacker C, Chisholm-Burns M, Demissie K. Prevalence and correlates of medication non-adherence among kidney transplant recipients more than 6 months post-transplant: a crosssectional study. BMC Nephrol 2013;14:261- 71.
20. Sankaranarayanan J, Collier D, Furasek A, Reardon T, Smith LM, McCartan M, et al. Rurality and other factors associated with adherence to immunosuppressant medications in community-dwelling solid-organ transplant recipients. Res Social Admin Pharm 2012; 8(3):228-39.
21. Jamieson S. Likert scales: how to (ab) use them. Med Educ 2004;38(12):1217-8.
22. Tavşanel E. [Basic concepts related to measurement]. Data analysis. Tutumların Ölçülmesi ve SPSS ile Veri Analizi. 1. Baskı. Ankara: Atlas Yayınevi; 2002. p.46-51.
23. Schreiber JB, Nora A, Stage FK, Barlow EA, King J. Reporting structural equation modeling and confirmatory factor analysis results: a review. J Educ Res 2006;99(6):323-38.
24. DiStefano C. The impact of categorization with confirmatory factor analysis. Structural Equation Modeling 2002;9(3):327-46.
25. Özabacı N. [The Turkish adaptation of the relationship quality scale: a validity and reliability study]. Education and Science 2011; 36(162):159-67.
26. Polit DF, Beck CT. The content validity index: are you sure you know what's being reported? Critique and recommendations. Res Nurs Health 2006;29(5):489-97.
27. Büyüköztürk Ş. [Factor analysis: basic concepts and the use of scale development]. Educational Administration of Theory and Practice 2002;32:470-83.
28. Ercan İ, Kan İ. [Reliability and validity in the scales]. Journal of Uludag University Medical Faculty 2004;30(3):211-6.
29. Daşdan Ada EN, Aşçı FH, Kazak Çetinkalp FZ, Altiparmak ME. [Validity and reliability of situational motivation scale for physical education class environment]. SPORMETRE Beden Eğitimi ve Spor Bilimleri Dergisi 2012; X(1):7-12.
30. Baykal Ü, Harmancı AK, Eşkin F, Altuntaş S, Sökmen S. [Student satisfaction scale-short form" validity-reliability study]. Journal of Anatolian Nursing and Health Sciences 2011; 14(4):60-8.
31. Tavakol M, Dennick R. Making sense of Cronbach's alpha. Int J Med Educ 2011;2:53-5.
32. Baykul Y. [Reliability]. Eğitimde ve Psikolojide Ölçme: Klasik Test Teorisi ve Uygulaması. 1. Baskı. Ankara: ÖSYM Yayınları; 2000. p.141- 95.
33. Chisholm MA, Kwong WJ, Spivey CA. Associations of characteristics of renal transplant recipents with clinicians' perceptions of adherence to immunosuppressant therapy. Transplantation 2007;84(9):1145-50.
34. Denhaerynck K, Steiger J, Bock A, SchäferKeller P, Köfer S, Thannberger N, et al. Prevalence and risk factors of non-adherence with immunosuppressive medication in kidney transplant patients. Am J Transplant 2007; 7(1):108-16.
35. Rosenberger J, Geckova AM, van Dijk J, Nagyova I, Roland R, van den Heuvel WJ, et al. Prevalence and characteristics of noncompliant behaviour and its risk factors in kidney transplant recipients. Transpl Int 2005; 18(9):1072-8.
36. Dharancy S, Giral M, Tetaz R, Fatras M, Dubel L, Pageaux GP. Adherence with immunosuppressive treatment after transplantation: results from the French trial PREDICT. Clin Transplant 2012;26(3):E293-9.
37. Rodrigue JR, Nelson DR, Hanto DW, Reed AI, Curry MP. Patient-reported immunosuppression nonadherence 6 to 24 months after liver transplant: association with pretrasplant pychological factors and perceptions of health status change. Prog Transplant 2013;23(4): 319-28.
38. Chisholm MA, Williamson GM, Lance CE, Mulloy LL. Predicting adherence to immunosuppressant therapy: a prospective analysis of the theory of planned behavior. Nephrol Dial Transplant 2007;22(8):2339-48.

APA	karayurt o (2016). Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability. , 325 - 334.
Chicago	karayurt ozgul Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability. (2016): 325 - 334.
MLA	karayurt ozgul Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability. , 2016, ss.325 - 334.
AMA	karayurt o Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability. . 2016; 325 - 334.
Vancouver	karayurt o Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability. . 2016; 325 - 334.
IEEE	karayurt o "Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability." , ss.325 - 334, 2016.
ISNAD	karayurt, ozgul. "Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability". (2016), 325-334.

APA	karayurt o (2016). Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability. Türkiye Klinikleri Hemşirelik Bilimleri Dergisi, 8(4), 325 - 334.
Chicago	karayurt ozgul Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability. Türkiye Klinikleri Hemşirelik Bilimleri Dergisi 8, no.4 (2016): 325 - 334.
MLA	karayurt ozgul Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability. Türkiye Klinikleri Hemşirelik Bilimleri Dergisi, vol.8, no.4, 2016, ss.325 - 334.
AMA	karayurt o Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability. Türkiye Klinikleri Hemşirelik Bilimleri Dergisi. 2016; 8(4): 325 - 334.
Vancouver	karayurt o Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability. Türkiye Klinikleri Hemşirelik Bilimleri Dergisi. 2016; 8(4): 325 - 334.
IEEE	karayurt o "Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability." Türkiye Klinikleri Hemşirelik Bilimleri Dergisi, 8, ss.325 - 334, 2016.
ISNAD	karayurt, ozgul. "Immunosuppressant Therapy Adherence Scale for Transplant Recipients: The Study of Validity and Reliability". Türkiye Klinikleri Hemşirelik Bilimleri Dergisi 8/4 (2016), 325-334.