Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey

Hilal ÖZBEK, (Department of Pharmacognosy, Faculty of Pharmacy, Atatürk University, 25240 Erzurum, Türkiye)
Zühal GÜVENALP, (Department of Pharmacognosy, Faculty of Pharmacy, Atatürk University, 25240 Erzurum, Türkiye)
Temel ÖZEK, (Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Türkiye)
Handan G SEVİNDİK, (Department of Pharmacognosy, Faculty of Pharmacy, Atatürk University, 25240 Erzurum, Türkiye)
Hafize YUCA, (Department of Pharmacognosy, Faculty of Pharmacy, Atatürk University, 25240 Erzurum, Türkiye)
Kadir Ö. YERDELEN, (Atatürk Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya Ana Bilim Dalı, Erzurum, Türkiye)
Lütfiye Ömür DEMİREZER (Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Türkiye)
Records of Natural Products
3 1
Yıl: 2017 Cilt: 11 Sayı: 5 Sayfa Aralığı: 485 - 492 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey

Öz:
The essential oil was obtained by hydrodistillation from the aerial parts of Origanum rotundifolium Boiss. Its chemical content and composition were analyzed by using a gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Total phenolic content of the essential oil was determined as 132.39 µg gallic acid equivalent by Folin–Ciocalteu’s method and the major component was identified as carvacrol (56.8 %) along with p-cymene (13.1 %), (Z)--ocimene (5.4 %), -caryophyllene (3.9 %), borneol (3.4 %) and thymol (3.2 %). After chemical characterization, the essential oil was evaluated for its antioxidant activity by DPPH free radical, superoxide anion radical and hydrogen peroxide scavenging activities as well as ferrous ion-chelating power test, ABTS radical cation decolorization assay and ferric thiocyanate methods. Besides antioxidant activity, acetylcholinesterase and butyrylcholinesterase inhibitory activities of the essential oil were also evaluated by Ellman’s method. It demonstrated inhibitory activities on AChE and BuChE, key enzymes in the pathogenesis of Alzheimer’s disease (AD), in addition to significant antioxidant activity.
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APA ÖZBEK H, GÜVENALP Z, ÖZEK T, SEVİNDİK H, YUCA H, YERDELEN K, DEMIREZER L (2017). Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey. , 485 - 492.
Chicago ÖZBEK HİLAL,GÜVENALP ZÜHAL,ÖZEK TEMEL,SEVİNDİK Handan G,YUCA Hafize,YERDELEN Kadir Ö.,DEMIREZER LUTFIYE OMUR Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey. (2017): 485 - 492.
MLA ÖZBEK HİLAL,GÜVENALP ZÜHAL,ÖZEK TEMEL,SEVİNDİK Handan G,YUCA Hafize,YERDELEN Kadir Ö.,DEMIREZER LUTFIYE OMUR Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey. , 2017, ss.485 - 492.
AMA ÖZBEK H,GÜVENALP Z,ÖZEK T,SEVİNDİK H,YUCA H,YERDELEN K,DEMIREZER L Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey. . 2017; 485 - 492.
Vancouver ÖZBEK H,GÜVENALP Z,ÖZEK T,SEVİNDİK H,YUCA H,YERDELEN K,DEMIREZER L Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey. . 2017; 485 - 492.
IEEE ÖZBEK H,GÜVENALP Z,ÖZEK T,SEVİNDİK H,YUCA H,YERDELEN K,DEMIREZER L "Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey." , ss.485 - 492, 2017.
ISNAD ÖZBEK, HİLAL vd. "Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey". (2017), 485-492.
APA ÖZBEK H, GÜVENALP Z, ÖZEK T, SEVİNDİK H, YUCA H, YERDELEN K, DEMIREZER L (2017). Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey. Records of Natural Products, 11(5), 485 - 492.
Chicago ÖZBEK HİLAL,GÜVENALP ZÜHAL,ÖZEK TEMEL,SEVİNDİK Handan G,YUCA Hafize,YERDELEN Kadir Ö.,DEMIREZER LUTFIYE OMUR Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey. Records of Natural Products 11, no.5 (2017): 485 - 492.
MLA ÖZBEK HİLAL,GÜVENALP ZÜHAL,ÖZEK TEMEL,SEVİNDİK Handan G,YUCA Hafize,YERDELEN Kadir Ö.,DEMIREZER LUTFIYE OMUR Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey. Records of Natural Products, vol.11, no.5, 2017, ss.485 - 492.
AMA ÖZBEK H,GÜVENALP Z,ÖZEK T,SEVİNDİK H,YUCA H,YERDELEN K,DEMIREZER L Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey. Records of Natural Products. 2017; 11(5): 485 - 492.
Vancouver ÖZBEK H,GÜVENALP Z,ÖZEK T,SEVİNDİK H,YUCA H,YERDELEN K,DEMIREZER L Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey. Records of Natural Products. 2017; 11(5): 485 - 492.
IEEE ÖZBEK H,GÜVENALP Z,ÖZEK T,SEVİNDİK H,YUCA H,YERDELEN K,DEMIREZER L "Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey." Records of Natural Products, 11, ss.485 - 492, 2017.
ISNAD ÖZBEK, HİLAL vd. "Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential oil of Origanum rotundifolium Boiss. from Turkey". Records of Natural Products 11/5 (2017), 485-492.
Sayfa Oluşturulma Tarihi
23-04-2024 5:10

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