Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus

Kadir BOZUKLUHAN, (University of Kafkas, Kars School of Higher Vocational Education, TR-36100 Kars - TURKEY)
Oğuz MERHAN, (University of Kafkas, Department of Biochemistry, Faculty of Veterinary Medicine, TR-36100 Kars - TURKEY)
HALİL İBRAHİM GÖKCE, (University of Mehmet Akif Ersoy, Department of Internal Medicine, Faculty of Veterinary Medicine, TR-15000 Burdur - TURKEY)
Metin ÖĞÜN, (University of Kafkas, Department of Biochemistry, Faculty of Veterinary Medicine, TR-36100 Kars - TURKEY)
Emine ATAKİŞİ, (University of Kafkas, Department of Biochemistry, Faculty of Veterinary Medicine, TR-36100 Kars - TURKEY)
Şemistan KIZILTEPE, (University of Kafkas, Department of Internal Medicine, Faculty of Veterinary Medicine, TR-36100 Kars - TURKEY)
Gürbüz GÖKÇE (University of Kafkas, Department of Internal Medicine, Faculty of Veterinary Medicine, TR-36100 Kars - TURKEY)
Kafkas Üniversitesi Veteriner Fakültesi Dergisi
11 0
Yıl: 2018 Cilt: 24 Sayı: 3 Sayfa Aralığı: 437 - 441 Metin Dili: İngilizce DOI: 10.9775/kvfd.2017.19167 İndeks Tarihi: 04-12-2018

Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus

Öz:
The aim of the present study was to determine oxidative stress and acute phase response in naturally infected sheep with poxvirus. For thispurpose, 20 poxvirus infected and 10 clinically healthy sheep were used in the study. In these animals, alkaline phosphatase (ALP), aspartateaminotransferase (AST) activity, haptoglobin, ceruloplasmin, urea, creatinine, albumin, iron (Fe), malondialdehyde (MDA) and reducedglutathione (GSH) concentrations were determined. The present study determined that the concentrations of haptoglobin, ceruloplasmin,urea, creatinine, MDA and ALP, AST activity were significantly increased, and albumin, Fe and GSH concentrations were significantly decreasedin the sheeppox virus infected group compared to the control group. Results of this study indicated that oxidative stress and acute phase response develop in sheep infected with poxvirus.
Anahtar Kelime:

Konular: Ziraat Mühendisliği Veterinerlik

Poksvirüs İle Doğal Enfekte Koyunlarda, Bazı Akut Faz Proteinler, Biyokimyasal Parametreler ve Oksidatif Stresin Belirlenmesi

Öz:
Çalışma poksvirüs ile doğal enfekte koyunlarda, oksidatif stres ve akut faz cevabı belirlemek amacıyla yapıldı. Çalışmada 20 adet çiçek hastalığı ile enfekte ve 10 adet klinik olarak sağlıklı koyun kullanıldı. Hayvanlarda alkalen fosfataz (ALP), aspartat aminotransferaz (AST) aktivitesi, haptoglobin, seruloplazmin, üre, kreatinin, albümin, demir (Fe), malondialdehit (MDA) ve redükte glutatyon (GSH) konsantrasyonları belirlendi. Çalışmada, poksvirus ile enfekte koyunlar ile kontrol grubundaki hayvanlar karşılaştırıldığında haptoglobin, seruloplazmin, üre, kreatinin, MDA değerleri ile ALP ve AST aktivitelerinin yükseldiği, albümin, Fe ve GSH konsantrasyonunun ise kontrol grubuna göre düştüğü belirlendi. Bu çalışmada poksvirus ile enfekte koyunlarda akut faz yanıtın oluştuğu ve oksidatif stresin geliştiği kanısına varıldı.
Anahtar Kelime:

Konular: Ziraat Mühendisliği Veterinerlik
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • Akaike T, Maeda H: Nitric oxide and virus infection. Immunology, 101, 300-308, 2000. DOI: 10.1046/j.1365-2567.2000.00142.x
  • Lykkesfeldt J, Svendsen O: Oxidants and antioxidants in disease: Oxidative stress in farm animals. Vet J, 173, 502-511, 2007. DOI: 10.1016/j. tvjl.2006.06.005
  • Aral H: Laboratory in diagnosis and monitoring of systemic inflammatory response syndrome or sepsis. Eur J Basic Med Sci, 5, 10-20, 2015. DOI: 10.15197/sabad.2.5.02
  • Gokce HI, Woldehiwet Z: The effects of Ehrlichia (Cytoecetes) phagochytophila on the clinical chemistry of sheep and goats. J Vet Med, 46, 93-103, 1999. DOI: 10.1111/j.0931-1793.1999.00210.x
  • Gruys E, Obwolo MJ, Toussaint MJM: Diagnostic significance of the major acute phase proteins in veterinary clinical chemistry: A review. Vet Bull, 64, 1009-1018, 1994.
  • Russell KE, Roussel AJ: Evaluation of the ruminant serum chemistry profile. Vet Clin North Am: Food Anim Pract, 23, 403-426, 2007. DOI: 10.1016/j.cvfa.2007.07.003
  • Tennant BC, Center SA: Hepatic function. In, Kaneko JJ, Harvey JW, Bruss ML (Eds): Clinical Biochemistry of Domestic Animals. 6th ed., 379- 412, Academic Press, New York, 2008.
  • Cerone SI, Sansinanea AS, Streitenberger SA, Garcia MC, Auza NJ: Cytochrome c oxidase, Cu, Zn-superoxide dismutase, and ceruloplasmin activities in copper-deficient bovines. Biol Trace Elem Res, 73, 269-278, 2000. DOI: 10.1385/BTER:73:3:269
  • Fagliari JJ, McClenahan D, Evanson OA, Weiss DJ: Changes in plasma protein concentrations in ponies with experimentally induced alimentary laminitis. Am J Vet Res, 59, 1234-1237, 1998.
  • Merhan O, Bozukluhan K, Kiziltepe S, Gokce HI: Investigation of levels of haptoglobin, serum amyloid A, ceruloplasmin and albumin in cattle with foot-and-mouth disease. Isr J Vet Med, 72, 14-17, 2017.
  • Eckersall PD, Conner JG: Bovine and canine acute phase proteins Vet Res Commun, 12, 169-178, 1988.
  • Bozukluhan K, Merhan O, Özcan A, Gökçe Hİ, Gökçe G: Investigation of the levels of serum haptoglobin, oxidative indicators and some biochemical parameters in calves naturally infected with Toxocara vitulorum. Vet J Ankara Univ, 64, 75-79, 2017. DOI: 10.1501/ vetfak_0000002778
  • Kaya S, Merhan O, Kacar C, Colak A, Bozukluhan K: Determination of ceruloplasmin, some other acute phase proteins, and biochemical parameters in cows with endometritis. Veterinary World, 9, 1056-1062, 2016. DOI: 10.14202/vetworld.2016.1056-1062
  • Kuru M, Merhan O, Kaya S, Oral H, Kukurt A: The effect of short term progesterone-releasing intravaginal device treatment on acute inflamation markers for Holstein heifers. Rev Med Vet, 166 (11-12): 336- 340, 2015.
  • Merhan O, Bozukluhan K, Gokce HI: Acute phase proteins and biochemical and oxidative stress parameters in Hypoderma spp. infested cattle. J Hellenic Vet Med Soc, 68, 535-540, 2017. DOI:10.12681/jhvms. 16049
  • Pradeep M: Application of acute phase proteins as biomarkers in modern veterinary practice. Ind J Vet Anim Sci Res, 43, 1-13, 2014.
  • Murata H, Shimada N, Yoshioka M: Current research on acute phase proteins in veterinary diagnosis: An overview. Vet J, 168, 28-40, 2004. DOI: 10.1016/S1090-0233(03)00119-9
  • Yoshioka T, Kawada K, Shimada T, Mori M: Lipid peroxidation in maternal and cord blood and protective mechanism against activatedoxygen toxicity in the blood. Am J Obstet Gynecol, 135, 372-376, 1979. DOI: 10.1016/0002-9378(79)90708-7
  • Beutler E, Duron O, Kelly BM: Improved method for the determination of blood glutathione. J Lab Clin Med, 61, 882-888, 1963.
  • Skinner JG, Brown RA, Roberts L: Bovine haptoglobin response in clinically defined field conditions. Vet Rec, 128, 147-149, 1991. DOI: 10.1136/vr.128.7.147
  • Colombo JP, Richterich R: Zur bestimmung des caeruloplasmin im plasma [on the determination of ceruloplasmin in plasma]. Schweiz Med Wochenschr, 23, 715-720, 1964.
  • Sezer K, Keskin M: Role of the free oxygen radicals on the pathogenesis of the diseases. FÜ Sağ Bil Vet Derg, 28, 49-56, 2014.
  • Nisbet C, Cenesiz S, Acici M, Umur S: Determination of the serum malondialdehyde, ceruloplasmin, adenosine deaminase levels in cattle with cystic echinococcosis. J Fac Vet Med Univ Erciyes, 5, 1-4, 2008.
  • Kirmizigul AH, Ogun M, Ozen H, Erkilic EE, Gokce E, Karaman M, Kukurt A: Oxidative stress and total sialic acid levels in sheep naturally infected with pox virus. Pak Vet J, 36, 312-315, 2016.
  • Birben E, Sahiner UM, Sackesen C, Erzurum S, Kalayci O: Oxidative stress and antioxidant defense. World Allergy Organ J, 5, 9-19, 2012.
  • Issi M, Gul Y, Yilmaz S: Clinical, haematological and antioxidant status in naturally poxvirus infected sheep. Revue Med Vet, 159, 54-58, 2008.
  • Akaike T: Role of free radicals in viral pathogenesis and mutation. Rev Med Virol, 11, 87-101, 2001. DOI: 10.1002/rmv.303
  • Tothova C, Nagy O, Kovac G: Acute phase proteins and their use in the diagnosis of diseases in ruminants: A review. Vet Med, 59, 163-180, 2014.
  • Gruys E, Toussaint MJM, Niewold TA, Koopmans SJ: Acute phase reaction and acute phase proteins. J Zhejiang Univ Sci B, 6, 1045-1056, 2005.
  • Toussaint MJM, van Ederen AM, Gruys E: Implication of clinical pathology in assessment of animal health and in animal production and meat inspection. Comp Haematol Internat, 5, 149-157, 1995. DOI: 10.1007/ BF00368037
  • Petersen HH, Nielsen JP, Heegaard PMH: Application of acute phase protein measurements in veterinary clinical chemistry. Vet Res, 35, 163- 187, 2004. DOI: 10.1051/vetres:2004002
  • Cray C, Zaias J, Altman NH: Acute phase response in animals: A review. Comp Med, 59, 517-526, 2009.
  • Çenesiz M, Sağkan Öztürk A, Dalğın D, Yarım GF, Çiftçi G, Özdemir R, Güzel M, Kazak F, Çenesiz S: Investigation of acute phase reactants and antioxidant capacity in calves infected with Cryptosporidium parvum. Kafkas Univ Vet Fak Derg, 23, 481-485, 2017. DOI: 10.9775/kvfd.2016.17183
  • Buller RM, Palumbo GJ: Poxvirus pathogenesis. Microbiol Rev, 55, 80- 122, 1991.
  • Bowden TR, Babiuk SL, Parkyn GR, Copps JS, Boyle DB: Capripoxvirus tissue tropism and shedding: A quantitative study in experimentally infected sheep and goats. Virology, 371, 380-393, 2008. DOI: 10.1016/j. virol.2007.10.002
  • Altınel C: Investigation of some biochemical parameters in blood serum of sheep pox vaccinated and infected sheep. Pendik Vet Microbiol J, 24, 203-219, 1993.
  • Constable PD, Hinchcliff KW, Done SH, Grünberg W: Sheeppox and goatpox. In, Veterinary Medicine: A Textbook of the Diseases of Cattle, Horses, Sheep, Pigs, and Goats. 11th ed., 1591-1593, Elsevier, China, 2017.
  • Plowright W, Macleod WG, Ferris RD: The pathogenesis of sheep pox in the skin of sheep. J Comp Path, 146, 97-105, 2012. DOI: 10.1016/j. jcpa.2011.12.004
  • Beytut E: Sheep pox virus induces proliferation of type II pneumocytes in the lungs. J Comp Path, 143, 132-141, 2010. DOI: 10.1016/j.jcpa. 2010.01.014
APA BOZUKLUHAN K, MERHAN O, GÖKCE H, ÖĞÜN M, ATAKİŞİ E, KIZILTEPE Ş, GÖKÇE G (2018). Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus. , 437 - 441. 10.9775/kvfd.2017.19167
Chicago BOZUKLUHAN KADIR,MERHAN OĞUZ,GÖKCE HALİL İBRAHİM,ÖĞÜN Metin,ATAKİŞİ Emine,KIZILTEPE Şemistan,GÖKÇE Gürbüz Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus. (2018): 437 - 441. 10.9775/kvfd.2017.19167
MLA BOZUKLUHAN KADIR,MERHAN OĞUZ,GÖKCE HALİL İBRAHİM,ÖĞÜN Metin,ATAKİŞİ Emine,KIZILTEPE Şemistan,GÖKÇE Gürbüz Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus. , 2018, ss.437 - 441. 10.9775/kvfd.2017.19167
AMA BOZUKLUHAN K,MERHAN O,GÖKCE H,ÖĞÜN M,ATAKİŞİ E,KIZILTEPE Ş,GÖKÇE G Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus. . 2018; 437 - 441. 10.9775/kvfd.2017.19167
Vancouver BOZUKLUHAN K,MERHAN O,GÖKCE H,ÖĞÜN M,ATAKİŞİ E,KIZILTEPE Ş,GÖKÇE G Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus. . 2018; 437 - 441. 10.9775/kvfd.2017.19167
IEEE BOZUKLUHAN K,MERHAN O,GÖKCE H,ÖĞÜN M,ATAKİŞİ E,KIZILTEPE Ş,GÖKÇE G "Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus." , ss.437 - 441, 2018. 10.9775/kvfd.2017.19167
ISNAD BOZUKLUHAN, KADIR vd. "Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus". (2018), 437-441. https://doi.org/10.9775/kvfd.2017.19167
APA BOZUKLUHAN K, MERHAN O, GÖKCE H, ÖĞÜN M, ATAKİŞİ E, KIZILTEPE Ş, GÖKÇE G (2018). Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 24(3), 437 - 441. 10.9775/kvfd.2017.19167
Chicago BOZUKLUHAN KADIR,MERHAN OĞUZ,GÖKCE HALİL İBRAHİM,ÖĞÜN Metin,ATAKİŞİ Emine,KIZILTEPE Şemistan,GÖKÇE Gürbüz Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 24, no.3 (2018): 437 - 441. 10.9775/kvfd.2017.19167
MLA BOZUKLUHAN KADIR,MERHAN OĞUZ,GÖKCE HALİL İBRAHİM,ÖĞÜN Metin,ATAKİŞİ Emine,KIZILTEPE Şemistan,GÖKÇE Gürbüz Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, vol.24, no.3, 2018, ss.437 - 441. 10.9775/kvfd.2017.19167
AMA BOZUKLUHAN K,MERHAN O,GÖKCE H,ÖĞÜN M,ATAKİŞİ E,KIZILTEPE Ş,GÖKÇE G Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2018; 24(3): 437 - 441. 10.9775/kvfd.2017.19167
Vancouver BOZUKLUHAN K,MERHAN O,GÖKCE H,ÖĞÜN M,ATAKİŞİ E,KIZILTEPE Ş,GÖKÇE G Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2018; 24(3): 437 - 441. 10.9775/kvfd.2017.19167
IEEE BOZUKLUHAN K,MERHAN O,GÖKCE H,ÖĞÜN M,ATAKİŞİ E,KIZILTEPE Ş,GÖKÇE G "Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus." Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 24, ss.437 - 441, 2018. 10.9775/kvfd.2017.19167
ISNAD BOZUKLUHAN, KADIR vd. "Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus". Kafkas Üniversitesi Veteriner Fakültesi Dergisi 24/3 (2018), 437-441. https://doi.org/10.9775/kvfd.2017.19167
Sayfa Oluşturulma Tarihi
23-04-2024 6:57

İLETİŞİM

TÜBİTAK ULAKBİM TR Dizin

Yüzüncüyıl, İşçi Blokları Mahallesi

Muhsin Yazıcıoğlu Caddesi No:51/C

06530 Çankaya / ANKARA +90 (312) 298 92 00

trdizin@tubitak.gov.tr

TÜBİTAK ULAKBİM Ulusal Akademik Ağ ve Bilgi Merkezi Cahit Arf Bilgi Merkezi © Tüm Hakları Saklıdır. Gizlilik Politikası Kullanım Şartları