Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri
Yıl: 2017 Cilt: 21 Sayı: 1 Sayfa Aralığı: 19 - 29 Metin Dili: Türkçe DOI: 10.12991/marupj.259877 İndeks Tarihi: 16-01-2019
Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri
Öz: Polifenoller bitkilerin kök, tohum, çiçek, yaprak, dal ve gövde gibi tüm kısımlarında ve çay, kahve, şarap gibi bitkisel ürünlerde yüksek miktarlarda bulunurlar. Polifenollerin antioksidan, antikanser, anti-inflamatuar, anti-koagülan ve anti-mikrobiyal etkileri olduğunu belirten çok sayıda araştırma bulunmaktadır. Son yıllarda araştırıcılar bu bileşiklerin anti-kanser etkisinde rol alan moleküler mekanizmaların aydınlatılmasına yönelmiştir. Ancak, hem etki mekanizmalarının kanser hücre tipine göre farklılık göstermesi hem de biyoyararlanımlarının sınırlı olması, biyoyararlanımı arttıracak ve kanser hücre tipine spesifik yaklaşımların geliştirilmesini gerekli kılmaktadır. Bu derlemede, kurkumin, kuersetin ve çay kateşinlerinin yapısal özellikleri, biyoyararlanımları, biyolojik etkileri ve anti-kanser etki mekanizmaları tartışılmıştır.
Anahtar Kelime: Konular:
Anti-cancer effects of curcumin, quercetin and tea catechins
Öz: Polyphenols are present in high amounts in all parts of plants including roots, seeds, flowers, leaves, branches and trunk as well as plant derived products such as tea, coffee and wine. Extensive amount of information is available on biological effects of polyphenols including antioxidant, anti-cancer, antiinflammatory, anti-coagulant and anti-microbial activities. In recent years, researchers have turned their interest towards identifying molecular mechanisms underlying the anti-cancer effects of these compounds. However, the limited bioavailability of polyphenols and the existence of differences in cancer cells in terms of intracellular mechanisms affected has necessitated the use of specific approaches to individual cancer cell types as well as methods of increasing bioavailability. In this review, the structures, bioavailability, biological activities and molecular mechanisms of anti-cancer effects of curcumin, quercetin and tea catechins are discussed.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
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| APA | YALÇIN A, Yılmaz Göler A, ALTUNDAĞ E, KOÇTÜRK A (2017). Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri. , 19 - 29. 10.12991/marupj.259877 |
| Chicago | YALÇIN A. Süha,Yılmaz Göler Ayşe Mine,ALTUNDAĞ Ergül Mutlu,KOÇTÜRK AYŞE SEMRA Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri. (2017): 19 - 29. 10.12991/marupj.259877 |
| MLA | YALÇIN A. Süha,Yılmaz Göler Ayşe Mine,ALTUNDAĞ Ergül Mutlu,KOÇTÜRK AYŞE SEMRA Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri. , 2017, ss.19 - 29. 10.12991/marupj.259877 |
| AMA | YALÇIN A,Yılmaz Göler A,ALTUNDAĞ E,KOÇTÜRK A Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri. . 2017; 19 - 29. 10.12991/marupj.259877 |
| Vancouver | YALÇIN A,Yılmaz Göler A,ALTUNDAĞ E,KOÇTÜRK A Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri. . 2017; 19 - 29. 10.12991/marupj.259877 |
| IEEE | YALÇIN A,Yılmaz Göler A,ALTUNDAĞ E,KOÇTÜRK A "Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri." , ss.19 - 29, 2017. 10.12991/marupj.259877 |
| ISNAD | YALÇIN, A. Süha vd. "Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri". (2017), 19-29. https://doi.org/10.12991/marupj.259877 |
| APA | YALÇIN A, Yılmaz Göler A, ALTUNDAĞ E, KOÇTÜRK A (2017). Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri. Marmara Pharmaceutical Journal, 21(1), 19 - 29. 10.12991/marupj.259877 |
| Chicago | YALÇIN A. Süha,Yılmaz Göler Ayşe Mine,ALTUNDAĞ Ergül Mutlu,KOÇTÜRK AYŞE SEMRA Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri. Marmara Pharmaceutical Journal 21, no.1 (2017): 19 - 29. 10.12991/marupj.259877 |
| MLA | YALÇIN A. Süha,Yılmaz Göler Ayşe Mine,ALTUNDAĞ Ergül Mutlu,KOÇTÜRK AYŞE SEMRA Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri. Marmara Pharmaceutical Journal, vol.21, no.1, 2017, ss.19 - 29. 10.12991/marupj.259877 |
| AMA | YALÇIN A,Yılmaz Göler A,ALTUNDAĞ E,KOÇTÜRK A Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri. Marmara Pharmaceutical Journal. 2017; 21(1): 19 - 29. 10.12991/marupj.259877 |
| Vancouver | YALÇIN A,Yılmaz Göler A,ALTUNDAĞ E,KOÇTÜRK A Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri. Marmara Pharmaceutical Journal. 2017; 21(1): 19 - 29. 10.12991/marupj.259877 |
| IEEE | YALÇIN A,Yılmaz Göler A,ALTUNDAĞ E,KOÇTÜRK A "Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri." Marmara Pharmaceutical Journal, 21, ss.19 - 29, 2017. 10.12991/marupj.259877 |
| ISNAD | YALÇIN, A. Süha vd. "Kurkumin, Kuersetin ve Çay Kateşinlerinin Anti-Kanser Etkileri". Marmara Pharmaceutical Journal 21/1 (2017), 19-29. https://doi.org/10.12991/marupj.259877 |
