Yıl: 2017 Cilt: 41 Sayı: 4 Sayfa Aralığı: 214 - 218 Metin Dili: İngilizce İndeks Tarihi: 27-03-2019

Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara

Öz:
Objective: Leishmaniasis is an infectious disease that is caused by a protozoan parasite of the Leishmania genus and that occurs worldwide.Leishmaniasis is endemic in southeastern Turkey and the neighboring Middle Eastern countries. The purpose of this study was to describethe clinical characteristics of patients admitted to our hospital with a diagnosis of cutaneous leishmaniasis (CL).Methods: A total of 16 CL patients [11 (69%) boys and five (31%) girls] were admitted between January 2014 and December 2015. The dataof the patients were retrospectively recorded from their medical records.Results: Their mean age was 74.3±32.3 months (range: 1–10.5 years). Double lesions were most commonly seen in eight (50%) patients. Theface and neck was the most commonly involved site (87.5% of the patients). Skin smears for a parasitological examination were positive innine (56%) patients. Two patients (12.5%) with limb lesions were treated with intralesional meglumine antimoniate. Fourteen patients weretreated with systemic agents.Conclusion: We felt that the increase in human movement that include travels and forced migration due to the war might make it possiblefor CL to appear in non-endemic provinces such as Ankara. In particular, in patients with painless cutaneous lesion(s) who came from endemicareas such as Syria, CL should be kept in mind by the clinicians that residing in even non-endemic areas .
Anahtar Kelime:

Konular: Parazitoloji

Çocuklarda Kutanöz Leishmaniasis: Tek Merkez Deneyimi

Öz:
Amaç: Leishmaniasis, tüm dünyada görülen, Leishmania türlerinin etken olduğu paraziter bir enfeksiyon hastalığıdır. Leishmaniasis, Tür- kiye’nin Güney Doğu’sunda ve komşu Orta Doğu ülkelerinde endemiktir. Bu çalışma ile, Suriye’deki savaştan sonra hastanemize kutanöz leishmaniasis (KL) tanısı ile kabul edilen hastaların klinik özelliklerini tanımlamayı hedefledik. Yöntemler: Ocak 2014 ile Aralık 2015 arasında Dr. Sami Ulus Kadın Doğum, Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi’ne toplam 16 kutanöz leyşmanyoz hastası (11 (%69) erkek and 5 (%31) kız) kabul edilmiştir. Hastaların bilgileri tıbbi kayıtlarından retrosepktif olarak değerlendirildi. Bulgular: Hastaların ortalama yaşı 74,3±32,3 ay olarak tespit edilirken (Aralık: 1-10,5 yaş) hastalarda en sık tutuluan vücut bölgesinin yüz ve boyun (%87,5) bölgesi olduğu belirlenmiştir. Ciltten alınan örneklerin yaymalarının mikroskobik incelemesinde 9 (%56) hastada amastigot şe- killeri görülmüştür. Ekstemitelerde lezyonu olan 2 (%12,5) hasta intralezyonel meglümin antimonat ile tedavi edilmiştir. On dört hasta sistemik olarak tedavi edilmiştir. Sonuç: Artan insan hareketleri ve göçler nedeniyle Ankara gibi hastalığın endemik olmadığı bölgelerde de KL vakaları görülebilir. Özellikle, Suriye gibi endemik bölgelerden gelen, ağrısız cilt lezyonları ile başvuran hastalarda endemik olmayan bölgelerde de çocuk hekimleri tarfın- dan KL akılda tutulmalıdır.
Anahtar Kelime:

Konular: Parazitoloji
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • World Health Organization. Manual for case management of cu- taneous leishmaniasis in the WHO Eastern Mediterranean Region. Draft 14 2012. Cairo, Egypt. Available from: http://www.emro.who. int/images/stories/zoonoses/Manual_leishmaniasis_edited_MB_ draft_for_Web_1_5_13.pdf
  • Gürel MS, Yeşilova Y, Olgen MK, Ozbel Y. [Cutaneous leishmaniasis in Turkey]. Turkiye Parazitol Derg 2012; 36: 121-9. [CrossRef]
  • Sharara SL, Kanj SS. War and infectious diseases: challenges of the Syrian civil war. PLoS Pathog 2014; 10: e1004438. [CrossRef]
  • Hayani K, Dandashli A, Weisshaar E. Cutaneous leishmaniasis in Syria: clinical features, current status and the effects of war. Acta Derm Venereol 2015; 95: 62-6. [CrossRef]
  • Pace D. Leishmaniasis. J Infect 2014; 69 Suppl 1: 10-8. [CrossRef]
  • Talari SA, Talaei R, Shajari G, Vakili Z, Taghaviardakani A. Childhood cutaneous leishmaniasis: report of 117 cases from Iran. Korean J Parasitol 2006; 44: 355-60. [CrossRef]
  • Aksoy M, Doni N, Ozkul HU, Yesilova Y, Ardic N, Yesilova A, et al. Pediatric Cutaneous Leishmaniasis in an Endemic Region in Turkey: A Retrospective Analysis of 8786 Cases during 1998-2014. PLoS Negl Trop Dis 2016; 10: e0004835. [CrossRef]
  • Saroufim M, Charafeddine K, Issa G, Khalifeh H, Habib RH, Berry A, et al. Ongoing epidemic of cutaneous leishmaniasis among Syrian refugees, Lebanon. Emerg Infect Dis 2014; 20: 1712-5. [CrossRef]
  • Özbilgin A, Çulha G, Uzun S, Harman M, Topal SG, Okudan F, et al. Leishmaniasis in Turkey: first clinical isolation of Leishmania major from 18 autochthonous cases of cutaneous leishmaniasis in four geographical regions. Trop Med Int Health 2016; 21: 783-91. [CrossRef]
  • World Health Organization. “Leishmaniasis”. Available from: http://www.who.int/gho/neglected_diseases/leishmaniasis/en/.
  • World Health Organization. “Leishmaniasis: number of cases of cutaneous leishmaniasis reported data by country”. Available from: http://apps.who.int/gho/data/view.main.NTDLEISHCNUMv.
  • AFAD, (2015), “Suriye Afet Raporu”. Available from: https://www. afad.gov.tr/TR/IcerikDetay1.aspx?ID=16&IcerikID=747.
  • Layegh P, Khademi Z, Afzal Aghaee M, Moghiman T. Systemic Me- glumine Antimoniate in Cutaneous Leishmaniasis of Children: Clinical and Laboratory Complications. J Pediatric Infect Dis Soc 2015; 4: 356-8. [CrossRef]
  • Crowe A, Slavin J, Stark D, Aboltins C. A case of imported Leishma- nia infantum cutaneous leishmaniasis; an unusual presentation occurring 19 years after travel. BMC Infect Dis 2014; 14: 597. [CrossRef]
  • Lopes L, Vasconcelos P, Borges-Costa J, Soares-Almeida L, Campino L, Filipe P. An atypical case of cutaneous leishmaniasis caused by Leishmania infantum in Portugal. Dermatol Online J 2013; 19: 20407.
  • Al-Natour SH. Update in the treatment of cutaneous leishmaniasis. J Family Community Med 2009; 16: 41-7.
APA kaman a, Tanır G, GÖKÇE GAYRETLİ AYDIN Z, METİN AKCAN Ö, AYDIN-TEKE T, NUR ÖZ F, MUNGAN M (2017). Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara. , 214 - 218.
Chicago kaman ayse,Tanır Gönül,GÖKÇE GAYRETLİ AYDIN Zeynep,METİN AKCAN ÖZGE,AYDIN-TEKE Türkan,NUR ÖZ Fatma,MUNGAN Mesut Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara. (2017): 214 - 218.
MLA kaman ayse,Tanır Gönül,GÖKÇE GAYRETLİ AYDIN Zeynep,METİN AKCAN ÖZGE,AYDIN-TEKE Türkan,NUR ÖZ Fatma,MUNGAN Mesut Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara. , 2017, ss.214 - 218.
AMA kaman a,Tanır G,GÖKÇE GAYRETLİ AYDIN Z,METİN AKCAN Ö,AYDIN-TEKE T,NUR ÖZ F,MUNGAN M Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara. . 2017; 214 - 218.
Vancouver kaman a,Tanır G,GÖKÇE GAYRETLİ AYDIN Z,METİN AKCAN Ö,AYDIN-TEKE T,NUR ÖZ F,MUNGAN M Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara. . 2017; 214 - 218.
IEEE kaman a,Tanır G,GÖKÇE GAYRETLİ AYDIN Z,METİN AKCAN Ö,AYDIN-TEKE T,NUR ÖZ F,MUNGAN M "Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara." , ss.214 - 218, 2017.
ISNAD kaman, ayse vd. "Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara". (2017), 214-218.
APA kaman a, Tanır G, GÖKÇE GAYRETLİ AYDIN Z, METİN AKCAN Ö, AYDIN-TEKE T, NUR ÖZ F, MUNGAN M (2017). Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara. Türkiye Parazitoloji Dergisi, 41(4), 214 - 218.
Chicago kaman ayse,Tanır Gönül,GÖKÇE GAYRETLİ AYDIN Zeynep,METİN AKCAN ÖZGE,AYDIN-TEKE Türkan,NUR ÖZ Fatma,MUNGAN Mesut Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara. Türkiye Parazitoloji Dergisi 41, no.4 (2017): 214 - 218.
MLA kaman ayse,Tanır Gönül,GÖKÇE GAYRETLİ AYDIN Zeynep,METİN AKCAN ÖZGE,AYDIN-TEKE Türkan,NUR ÖZ Fatma,MUNGAN Mesut Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara. Türkiye Parazitoloji Dergisi, vol.41, no.4, 2017, ss.214 - 218.
AMA kaman a,Tanır G,GÖKÇE GAYRETLİ AYDIN Z,METİN AKCAN Ö,AYDIN-TEKE T,NUR ÖZ F,MUNGAN M Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara. Türkiye Parazitoloji Dergisi. 2017; 41(4): 214 - 218.
Vancouver kaman a,Tanır G,GÖKÇE GAYRETLİ AYDIN Z,METİN AKCAN Ö,AYDIN-TEKE T,NUR ÖZ F,MUNGAN M Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara. Türkiye Parazitoloji Dergisi. 2017; 41(4): 214 - 218.
IEEE kaman a,Tanır G,GÖKÇE GAYRETLİ AYDIN Z,METİN AKCAN Ö,AYDIN-TEKE T,NUR ÖZ F,MUNGAN M "Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara." Türkiye Parazitoloji Dergisi, 41, ss.214 - 218, 2017.
ISNAD kaman, ayse vd. "Cutaneous Leishmaniasis in Pediatric Patients in a Single Tertiary Hospital in Ankara". Türkiye Parazitoloji Dergisi 41/4 (2017), 214-218.