Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis
Yıl: 2019 Cilt: 57 Sayı: 1 Sayfa Aralığı: 26 - 31 Metin Dili: İngilizce DOI: 10.4274/haseki.galenos.2018.4567 İndeks Tarihi: 04-11-2019
Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis
Öz: Aim: Whether it is possible to differentiate complicated fromuncomplicated acute appendicitis (AA) by using complete blood count(CBC) is controversial. In this study, we analysed the predictive value ofCBC in differentiating complicated from uncomplicated AA.Methods: In this retrospective study, we analyzed records of patientswho underwent appendectomy in our clinic between January 1, 2015and January 1, 2018. The demographic data and CBC reports werecollected.Results: Two hundred thirty-five patients underwent appendectomydue to AA. Of the 235 patients, 164 (69.8%) had non-complicatedand 71 (30.2%) had complicated AA. The mean white blood count(WBC), red cell distribution width (RDW), platelet and plateletcrit countwere significantly higher in patients with complicated AA than in thosewith uncomplicated AA (p=0.001; p<0.01, p=0.049, and p=0.006,respectively). Both the mean neutrophil count and percentage werestatistically higher in complicated AA patients (p=0.001 and p<0.01,respectively). The basophil-to-lymphocyte ratio (BLR) and neutrophilto-lymphocyteratio (NLR) were significantly higher in patients withcomplicated AA (p=0.001 and p<0.01, respectively). Logistic regressionanalysis showed that WBC and RDW were independent diagnosticfactors for complicated AA [odss ratio (OR) 5.079 (95% confidenceinterval (CI): 2.29-11.24 and OR 1.412 (95% CI: 1.1-1.98), respectively](p<0.001 and p=0.046, respectively). The sensitivity, specificity, positiveand negative predictive values in complicated AA for BLR were 67.35%,64.04%, 44.6% and 82%, and for NLR were 73.47%, 66.67%, 48.6%and 85.4%, respectively.Conclusion: Elevated NLR, BLR and RDW, WBC and neutrophil countmay help differentiate complicated from non-complicated AA.
Anahtar Kelime: Konular:
Tam Kan Sayımının Akut Komplike Apandisitin Tanısındaki Kestirim Değerinin Araştırılması
Öz: Amaç: Komplike akut apandisitin (AA) ayırıcı tanısında tam kan sayımının kullanılabileceği konusunda tartışmalar devam etmektedir. Bu çalışmada tam kan sayımının komplike AA ayırıcı tanısındaki kestirim değeri araştırıldı. Yöntemler: Ocak 2015 ile Ocak 2018 tarihleri arasında apendektomi ameliyatı olan hastaların dosyaları geriye dönük incelendi. Demografik verilerle tam kan sayımının sonuçları toplandı. Bulgular: İki yüz otuz beş hasta AA nedeni ile apendektomi ameliyatı oldu. Bu 235 hastadan, 164’ünde (%69,8) non-komplike AA tespit edilirken 71’inde (%30,2) komplike AA bulundu. Ortalama beyaz küre sayısı (WBC), kırmızı küre dağılım genişliği (RDW), trombositlerin sayımı ve plateletcrit serum düzeyleri komplike AA olan hastalarda anlamlı derecede yüksek (sırasıyla, p=0,001; p<0,001; p=0,049; p=0,006). Hem nötrofil sayısı hemde nötrofilin yüzdelik oranı komplike AA olan hastalarda anlamlı derecede yüksek bulundu (sırasıyla, p=0,001; p<0,01). Komplike olmayan AA’larla karşılaştırıldığında komplike AA olan hastalarda hem basofil-lenfosit oranı (BLR) hem de nötrofil-lenfosit oranı (NLR) anlamlı derecede yüksek bulundu (sırasıyla, p=0,001; p<0,01). Multivariant analiz ile yapılan incelemede WBC ve RDW’nin komplike AA’da bağımsız tanısal değeri olduğu tespit edildi [tahmini rölatif risk 5,079 %95 güven aralığı (GA): 2,29-11,24; p<0,001]; RDW için tahmini rölatif risk 1,412 (%95 GA:1,01-1,98; p=0,046). Komplike AA’da BLR için duyarlılık %67,35; özgüllük %64,04; pozitif kestirim değeri %44,6 ve negatif kestirim değeri %82 bulunurken NLR için duyarlılık %73,47; özgüllük %66,67; pozitif kestirim değeri %48,6 ve negatif kestirim değeri %85,4 olarak tespit edildi. Sonuç: Yüksek NLR BLR ve RDW değerleri ile birlikte artmış WBC ve nötrofil sayımı komplike AA’nın ayırıcı tanısında kullanılabilir.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | GÜNAY Y, taşdöven i, KOZAN R, KOCA Ş, Caglar E (2019). Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis. , 26 - 31. 10.4274/haseki.galenos.2018.4567 |
| Chicago | GÜNAY Yusuf,taşdöven ilhan,KOZAN Ramazan,KOCA ŞÜKRAN,Caglar Emrah Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis. (2019): 26 - 31. 10.4274/haseki.galenos.2018.4567 |
| MLA | GÜNAY Yusuf,taşdöven ilhan,KOZAN Ramazan,KOCA ŞÜKRAN,Caglar Emrah Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis. , 2019, ss.26 - 31. 10.4274/haseki.galenos.2018.4567 |
| AMA | GÜNAY Y,taşdöven i,KOZAN R,KOCA Ş,Caglar E Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis. . 2019; 26 - 31. 10.4274/haseki.galenos.2018.4567 |
| Vancouver | GÜNAY Y,taşdöven i,KOZAN R,KOCA Ş,Caglar E Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis. . 2019; 26 - 31. 10.4274/haseki.galenos.2018.4567 |
| IEEE | GÜNAY Y,taşdöven i,KOZAN R,KOCA Ş,Caglar E "Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis." , ss.26 - 31, 2019. 10.4274/haseki.galenos.2018.4567 |
| ISNAD | GÜNAY, Yusuf vd. "Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis". (2019), 26-31. https://doi.org/10.4274/haseki.galenos.2018.4567 |
| APA | GÜNAY Y, taşdöven i, KOZAN R, KOCA Ş, Caglar E (2019). Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis. Haseki Tıp Bülteni, 57(1), 26 - 31. 10.4274/haseki.galenos.2018.4567 |
| Chicago | GÜNAY Yusuf,taşdöven ilhan,KOZAN Ramazan,KOCA ŞÜKRAN,Caglar Emrah Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis. Haseki Tıp Bülteni 57, no.1 (2019): 26 - 31. 10.4274/haseki.galenos.2018.4567 |
| MLA | GÜNAY Yusuf,taşdöven ilhan,KOZAN Ramazan,KOCA ŞÜKRAN,Caglar Emrah Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis. Haseki Tıp Bülteni, vol.57, no.1, 2019, ss.26 - 31. 10.4274/haseki.galenos.2018.4567 |
| AMA | GÜNAY Y,taşdöven i,KOZAN R,KOCA Ş,Caglar E Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis. Haseki Tıp Bülteni. 2019; 57(1): 26 - 31. 10.4274/haseki.galenos.2018.4567 |
| Vancouver | GÜNAY Y,taşdöven i,KOZAN R,KOCA Ş,Caglar E Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis. Haseki Tıp Bülteni. 2019; 57(1): 26 - 31. 10.4274/haseki.galenos.2018.4567 |
| IEEE | GÜNAY Y,taşdöven i,KOZAN R,KOCA Ş,Caglar E "Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis." Haseki Tıp Bülteni, 57, ss.26 - 31, 2019. 10.4274/haseki.galenos.2018.4567 |
| ISNAD | GÜNAY, Yusuf vd. "Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis". Haseki Tıp Bülteni 57/1 (2019), 26-31. https://doi.org/10.4274/haseki.galenos.2018.4567 |
