Yıl: 2020 Cilt: 50 Sayı: 1 Sayfa Aralığı: 66 - 85 Metin Dili: İngilizce DOI: 10.3906/sag-1904-150 İndeks Tarihi: 27-04-2020

Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience

Öz:
Background/aim: Our purpose was to determine the efficacy of levodopa carbidopa intestinal gel (LCIG) in a series of Turkish patientswith Parkinson’s disease (PD).Materials and methods: We had telephone calls with 54 patients from 11 neurology centers who were on LCIG treatment, and 44patients or their caregivers were included in an eight-item survey between September 2015 and June 2016. The reliability and validity ofthe survey were evaluated with intraclass correlation coefficients for every question separately.Results: Average age of the patients were 63.48 and the duration of PD was 12.79 years. Average LCIG treatment period was 15.63months. Percentages of the patients who reported they were ‘better’ after LCIG treatment were as follows: 80% for time spent off, 55% fordyskinesia, 65% for tremor, 85% for gait disorder, 50% for pain, 50% for sleep disorders, 42.5% for depression, 32.5% for incontinence,and 70% for activities of daily living. Cronbach’s alpha was 0.795 and the intraclass correlation coefficient was reliable for the items.Conclusion: As detected by a survey performed by telephone calls with good interrater reliability, patients with PD improve with LCIGtreatment in many aspects of the disease.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA GÜLTEKİN M, Ulukan Ç, TEZCAN S, DOGU O, HANAĞASI H, BİLGİÇ B, BORA TOKCAER A, ÇAKMUR R, Elibol B, MİRZA M, GÜNAL D, ERER ÖZBEK Ç, Kenangil G, KUSBECI O, AKBOSTANCI M (2020). Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience. , 66 - 85. 10.3906/sag-1904-150
Chicago GÜLTEKİN Murat,Ulukan Çağrı,TEZCAN Sabiha,DOGU OKAN,HANAĞASI HAŞMET AYHAN,BİLGİÇ BAŞAR,BORA TOKCAER Ayse,ÇAKMUR Raif,Elibol Bulent,MİRZA Meral,GÜNAL DILEK,ERER ÖZBEK Çiğdem Sevda,Kenangil Gulay,KUSBECI Ozge Yilmaz,AKBOSTANCI Muhittin Cenk Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience. (2020): 66 - 85. 10.3906/sag-1904-150
MLA GÜLTEKİN Murat,Ulukan Çağrı,TEZCAN Sabiha,DOGU OKAN,HANAĞASI HAŞMET AYHAN,BİLGİÇ BAŞAR,BORA TOKCAER Ayse,ÇAKMUR Raif,Elibol Bulent,MİRZA Meral,GÜNAL DILEK,ERER ÖZBEK Çiğdem Sevda,Kenangil Gulay,KUSBECI Ozge Yilmaz,AKBOSTANCI Muhittin Cenk Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience. , 2020, ss.66 - 85. 10.3906/sag-1904-150
AMA GÜLTEKİN M,Ulukan Ç,TEZCAN S,DOGU O,HANAĞASI H,BİLGİÇ B,BORA TOKCAER A,ÇAKMUR R,Elibol B,MİRZA M,GÜNAL D,ERER ÖZBEK Ç,Kenangil G,KUSBECI O,AKBOSTANCI M Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience. . 2020; 66 - 85. 10.3906/sag-1904-150
Vancouver GÜLTEKİN M,Ulukan Ç,TEZCAN S,DOGU O,HANAĞASI H,BİLGİÇ B,BORA TOKCAER A,ÇAKMUR R,Elibol B,MİRZA M,GÜNAL D,ERER ÖZBEK Ç,Kenangil G,KUSBECI O,AKBOSTANCI M Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience. . 2020; 66 - 85. 10.3906/sag-1904-150
IEEE GÜLTEKİN M,Ulukan Ç,TEZCAN S,DOGU O,HANAĞASI H,BİLGİÇ B,BORA TOKCAER A,ÇAKMUR R,Elibol B,MİRZA M,GÜNAL D,ERER ÖZBEK Ç,Kenangil G,KUSBECI O,AKBOSTANCI M "Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience." , ss.66 - 85, 2020. 10.3906/sag-1904-150
ISNAD GÜLTEKİN, Murat vd. "Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience". (2020), 66-85. https://doi.org/10.3906/sag-1904-150
APA GÜLTEKİN M, Ulukan Ç, TEZCAN S, DOGU O, HANAĞASI H, BİLGİÇ B, BORA TOKCAER A, ÇAKMUR R, Elibol B, MİRZA M, GÜNAL D, ERER ÖZBEK Ç, Kenangil G, KUSBECI O, AKBOSTANCI M (2020). Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience. Turkish Journal of Medical Sciences, 50(1), 66 - 85. 10.3906/sag-1904-150
Chicago GÜLTEKİN Murat,Ulukan Çağrı,TEZCAN Sabiha,DOGU OKAN,HANAĞASI HAŞMET AYHAN,BİLGİÇ BAŞAR,BORA TOKCAER Ayse,ÇAKMUR Raif,Elibol Bulent,MİRZA Meral,GÜNAL DILEK,ERER ÖZBEK Çiğdem Sevda,Kenangil Gulay,KUSBECI Ozge Yilmaz,AKBOSTANCI Muhittin Cenk Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience. Turkish Journal of Medical Sciences 50, no.1 (2020): 66 - 85. 10.3906/sag-1904-150
MLA GÜLTEKİN Murat,Ulukan Çağrı,TEZCAN Sabiha,DOGU OKAN,HANAĞASI HAŞMET AYHAN,BİLGİÇ BAŞAR,BORA TOKCAER Ayse,ÇAKMUR Raif,Elibol Bulent,MİRZA Meral,GÜNAL DILEK,ERER ÖZBEK Çiğdem Sevda,Kenangil Gulay,KUSBECI Ozge Yilmaz,AKBOSTANCI Muhittin Cenk Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience. Turkish Journal of Medical Sciences, vol.50, no.1, 2020, ss.66 - 85. 10.3906/sag-1904-150
AMA GÜLTEKİN M,Ulukan Ç,TEZCAN S,DOGU O,HANAĞASI H,BİLGİÇ B,BORA TOKCAER A,ÇAKMUR R,Elibol B,MİRZA M,GÜNAL D,ERER ÖZBEK Ç,Kenangil G,KUSBECI O,AKBOSTANCI M Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience. Turkish Journal of Medical Sciences. 2020; 50(1): 66 - 85. 10.3906/sag-1904-150
Vancouver GÜLTEKİN M,Ulukan Ç,TEZCAN S,DOGU O,HANAĞASI H,BİLGİÇ B,BORA TOKCAER A,ÇAKMUR R,Elibol B,MİRZA M,GÜNAL D,ERER ÖZBEK Ç,Kenangil G,KUSBECI O,AKBOSTANCI M Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience. Turkish Journal of Medical Sciences. 2020; 50(1): 66 - 85. 10.3906/sag-1904-150
IEEE GÜLTEKİN M,Ulukan Ç,TEZCAN S,DOGU O,HANAĞASI H,BİLGİÇ B,BORA TOKCAER A,ÇAKMUR R,Elibol B,MİRZA M,GÜNAL D,ERER ÖZBEK Ç,Kenangil G,KUSBECI O,AKBOSTANCI M "Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience." Turkish Journal of Medical Sciences, 50, ss.66 - 85, 2020. 10.3906/sag-1904-150
ISNAD GÜLTEKİN, Murat vd. "Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience". Turkish Journal of Medical Sciences 50/1 (2020), 66-85. https://doi.org/10.3906/sag-1904-150