Yıl: 2019 Cilt: 34 Sayı: 3 Sayfa Aralığı: 168 - 173 Metin Dili: İngilizce DOI: 10.5505/tjo.2019.1955 İndeks Tarihi: 04-05-2020

Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group

Öz:
OBJECTIVERecent meta-analysis have not revealed any positive effects of postmastectomy radiotherapy (PMRT)on locoregional recurrence (LRR) or overall survival in axilla-negative patients. However, risk of LRRincreases to 15% in the presence of two or more adverse factors for the same patient group. In this study,PMRT indications and volume selections of radiation oncologists in Turkey for axilla-negative breastcancer was investigated.METHODSQuestionnaires were distributed to members of the breast cancer study group. Data of patients with axillary negative or isolated/micrometastasis and PMRT over 10 years (2006–2016) were collected from 10participating centers. Clinical and tumor histopathological features and treatment details of 185 patientswere analyzed.RESULTSThe median age of patients was 48 years. Ratio of early-stage patients was 60% (T1-15%,T2-45%). Therewere 147 (79%) negative cases, 32 (17%) with micrometastasis, and 6 (3%) with isolated tumor cells.Half of the patients had only their chest walls (CW) irradiated. Peripheral lymphatics were also includedin the rest. In Nmic cases, ratio of irradiation of supraclavicular and axillary lymph nodes with CW werestatistically significant compared to CW irradiation (72% and 28%, respectively; p=0.015).CONCLUSIONConsidering the low number of patients treated over 10 years in 10 different centers in Turkey, it can besaid that PMRT is often done in node-negative breast cancer. It is difficult to reach a definite conclusionfor patients with Nmic, due to lack of data from patients with PMRT. However, the general tendency isto irradiate peripheral lymphatics in Nmic cases if PMRT is to be performed.
Anahtar Kelime:

Konular: Onkoloji
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA ALTINOK A, GÜRSEL Ş, Ergen S, alanyali s, ozsaran z, Ay Eren A, METCALFE E, AKMANSU M, Tepetam H, ALTINOK P, ALTMIŞDÖRTOĞLU Ö, SERARSLAN A, BEŞE N (2019). Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group. , 168 - 173. 10.5505/tjo.2019.1955
Chicago ALTINOK Ayşe,GÜRSEL ŞÜKRİYE BİLGE,Ergen Sefika Arzu,alanyali senem,ozsaran zeynep,Ay Eren Ayfer,METCALFE Evrim,AKMANSU Müge,Tepetam Hüseyin,ALTINOK Pelin,ALTMIŞDÖRTOĞLU Özgür,SERARSLAN ALPARSLAN,BEŞE Nuran Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group. (2019): 168 - 173. 10.5505/tjo.2019.1955
MLA ALTINOK Ayşe,GÜRSEL ŞÜKRİYE BİLGE,Ergen Sefika Arzu,alanyali senem,ozsaran zeynep,Ay Eren Ayfer,METCALFE Evrim,AKMANSU Müge,Tepetam Hüseyin,ALTINOK Pelin,ALTMIŞDÖRTOĞLU Özgür,SERARSLAN ALPARSLAN,BEŞE Nuran Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group. , 2019, ss.168 - 173. 10.5505/tjo.2019.1955
AMA ALTINOK A,GÜRSEL Ş,Ergen S,alanyali s,ozsaran z,Ay Eren A,METCALFE E,AKMANSU M,Tepetam H,ALTINOK P,ALTMIŞDÖRTOĞLU Ö,SERARSLAN A,BEŞE N Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group. . 2019; 168 - 173. 10.5505/tjo.2019.1955
Vancouver ALTINOK A,GÜRSEL Ş,Ergen S,alanyali s,ozsaran z,Ay Eren A,METCALFE E,AKMANSU M,Tepetam H,ALTINOK P,ALTMIŞDÖRTOĞLU Ö,SERARSLAN A,BEŞE N Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group. . 2019; 168 - 173. 10.5505/tjo.2019.1955
IEEE ALTINOK A,GÜRSEL Ş,Ergen S,alanyali s,ozsaran z,Ay Eren A,METCALFE E,AKMANSU M,Tepetam H,ALTINOK P,ALTMIŞDÖRTOĞLU Ö,SERARSLAN A,BEŞE N "Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group." , ss.168 - 173, 2019. 10.5505/tjo.2019.1955
ISNAD ALTINOK, Ayşe vd. "Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group". (2019), 168-173. https://doi.org/10.5505/tjo.2019.1955
APA ALTINOK A, GÜRSEL Ş, Ergen S, alanyali s, ozsaran z, Ay Eren A, METCALFE E, AKMANSU M, Tepetam H, ALTINOK P, ALTMIŞDÖRTOĞLU Ö, SERARSLAN A, BEŞE N (2019). Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group. Türk Onkoloji Dergisi, 34(3), 168 - 173. 10.5505/tjo.2019.1955
Chicago ALTINOK Ayşe,GÜRSEL ŞÜKRİYE BİLGE,Ergen Sefika Arzu,alanyali senem,ozsaran zeynep,Ay Eren Ayfer,METCALFE Evrim,AKMANSU Müge,Tepetam Hüseyin,ALTINOK Pelin,ALTMIŞDÖRTOĞLU Özgür,SERARSLAN ALPARSLAN,BEŞE Nuran Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group. Türk Onkoloji Dergisi 34, no.3 (2019): 168 - 173. 10.5505/tjo.2019.1955
MLA ALTINOK Ayşe,GÜRSEL ŞÜKRİYE BİLGE,Ergen Sefika Arzu,alanyali senem,ozsaran zeynep,Ay Eren Ayfer,METCALFE Evrim,AKMANSU Müge,Tepetam Hüseyin,ALTINOK Pelin,ALTMIŞDÖRTOĞLU Özgür,SERARSLAN ALPARSLAN,BEŞE Nuran Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group. Türk Onkoloji Dergisi, vol.34, no.3, 2019, ss.168 - 173. 10.5505/tjo.2019.1955
AMA ALTINOK A,GÜRSEL Ş,Ergen S,alanyali s,ozsaran z,Ay Eren A,METCALFE E,AKMANSU M,Tepetam H,ALTINOK P,ALTMIŞDÖRTOĞLU Ö,SERARSLAN A,BEŞE N Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group. Türk Onkoloji Dergisi. 2019; 34(3): 168 - 173. 10.5505/tjo.2019.1955
Vancouver ALTINOK A,GÜRSEL Ş,Ergen S,alanyali s,ozsaran z,Ay Eren A,METCALFE E,AKMANSU M,Tepetam H,ALTINOK P,ALTMIŞDÖRTOĞLU Ö,SERARSLAN A,BEŞE N Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group. Türk Onkoloji Dergisi. 2019; 34(3): 168 - 173. 10.5505/tjo.2019.1955
IEEE ALTINOK A,GÜRSEL Ş,Ergen S,alanyali s,ozsaran z,Ay Eren A,METCALFE E,AKMANSU M,Tepetam H,ALTINOK P,ALTMIŞDÖRTOĞLU Ö,SERARSLAN A,BEŞE N "Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group." Türk Onkoloji Dergisi, 34, ss.168 - 173, 2019. 10.5505/tjo.2019.1955
ISNAD ALTINOK, Ayşe vd. "Postmastectomy Radiotherapy Decision for Patients without Lymph Node Metastases: Turkish Radiation Oncology Society Breast Cancer Working Group". Türk Onkoloji Dergisi 34/3 (2019), 168-173. https://doi.org/10.5505/tjo.2019.1955