Saliva profiles in children with congenital heart disease
Yıl: 2020 Cilt: 54 Sayı: 1 Sayfa Aralığı: 48 - 54 Metin Dili: İngilizce DOI: 10.26650/eor.20200087 İndeks Tarihi: 30-06-2020
Saliva profiles in children with congenital heart disease
Öz: The low salivary pH and buffering capacity are caused by using heart failuremedications. For this reason oral health should be supported in cardiac patients,it is necessary that they attend dental clinics for regular follow up. The aim of thisstudy is to evaluate the relationship between the salivary oxidative stress markersand salivary pH, salivary buffering capacity, salivary flow rate and dental caries ofchildren with congenital heart disease (CHD).Material and MethodsThis cross sectional study was carried out with 42 CHD and 42 healthy children. Theparticipants’ gender, age, general health and medications, and caries scores (dfs/DMFS) were written down, then their unstimulated saliva samples were collected.These specimens were evaluated in terms of the salivary secretion rate, salivarybuffering capacity, pH, protein levels, superoxide dismutase (SOD), ferric reducingantioxidant power (FRAP), the thiobarbituric acid reactive substances (TBARS),protein carbonyl, protein thiols, total sialic acid.ResultsBoth groups showed caries at similar levels. The salivary pH and buffering capacitywere significantly less in the children with CHD than in the controls. The levels ofTBARS and protein carbonyl were significantly higher in the children with CHDthan in the controls. There was not any significant difference relating to the meansalivary secretion rate, protein levels, SOD, FRAP, protein thiols and total sialic acid.ConclusionThe elevated TBARS and protein carbonyl levels in the patients with CHD wereobserved as an indicator of the free radical damage leading to oxidative stress.
Anahtar Kelime: .
Öz: Konjenital kalp hastalığına sahip çocuklarda tükürük profili. Amaç: Kalp hastalıklarında düzenli ilaç kullanımı ile düşük tükürük pH’sı ve tamponlama kapasitesi ortaya çıkmaktadır. Bu nedenle kardiyak hastalarda ağız sağlığı desteklenmelidir ve düzenli takip şarttır. Bu çalışmanın amacı, konjenital kalp hastalığı olan çocuklarda tükürük oksidatif stres belirteçleri ile tükürük pH, tükürük tamponlama kapasitesi, tükürük akış hızı ve diş çürüğü arasındaki ilişkiyi değerlendirmektir. Yöntemler: Bu kesitsel çalışma 42 konjenital kalp hastası ve 42 sağlıklı çocuk ile yapılmıştır. Katılımcıların cinsiyet, yaş, genel sağlık ve kullandıkları ilaçları ile çürük skorları (dfs / DMFS) kaydedilmiş, uyarılmamış tükürük örnekleri toplanmıştır. Bu örnekler tükürük sekresyon miktarı, tükürük tamponlama kapasitesi, pH, protein düzeyleri, süperoksit dismutaz (SOD), ferrik indirgeyici antioksidan güç (FRAP), tiyobarbitürik asit reaktif maddeler (TBARS), protein karbonil, protein tiyolleri ve toplam sialik asit açısından değerlendirilmiştir. Bulgular: Her iki grup da benzer oranlarda çürük olduğu saptanmıştır. Konjenital kalp hastalığına sahip çocuklarda tükürük pH’sı ve tamponlama kapasitesi kontrol grubuna göre anlamlı olarak daha az bulunmuştur. Konjenital kalp hastalığına sahip çocuklarda kontrol grubuna göre TBARS ve protein karbonil düzeyleri anlamlı olarak yüksek bulunmuştur. Ortalama tükürük sekresyon miktarı, protein düzeyleri, SOD, FRAP, protein tiyolleri ve toplam sialik asit ile ilgili anlamlı bir fark bulunmamıştır. Sonuç: Konjenital kalp hastalığına sahip çocuklarda yükselmiş TBARS ve protein karbonil düzeyleri, oksidatif strese yol açan serbest radikal hasarının bir göstergesi olarak gözlenmiştir. Anahtar Kelimeler: Tükürük kompozisyonu; antioksidant aktivite; çürük risk faktörleri; konjenital kalp hastalığı; çocuk dişhekimliği
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | KORUYUCU M, Batu S, Bayram M, USLU E, GÜVEN Y, Seymen F (2020). Saliva profiles in children with congenital heart disease. , 48 - 54. 10.26650/eor.20200087 |
| Chicago | KORUYUCU Mine,Batu Sule,Bayram Merve,USLU Ezel,GÜVEN Yegane,Seymen Figen Saliva profiles in children with congenital heart disease. (2020): 48 - 54. 10.26650/eor.20200087 |
| MLA | KORUYUCU Mine,Batu Sule,Bayram Merve,USLU Ezel,GÜVEN Yegane,Seymen Figen Saliva profiles in children with congenital heart disease. , 2020, ss.48 - 54. 10.26650/eor.20200087 |
| AMA | KORUYUCU M,Batu S,Bayram M,USLU E,GÜVEN Y,Seymen F Saliva profiles in children with congenital heart disease. . 2020; 48 - 54. 10.26650/eor.20200087 |
| Vancouver | KORUYUCU M,Batu S,Bayram M,USLU E,GÜVEN Y,Seymen F Saliva profiles in children with congenital heart disease. . 2020; 48 - 54. 10.26650/eor.20200087 |
| IEEE | KORUYUCU M,Batu S,Bayram M,USLU E,GÜVEN Y,Seymen F "Saliva profiles in children with congenital heart disease." , ss.48 - 54, 2020. 10.26650/eor.20200087 |
| ISNAD | KORUYUCU, Mine vd. "Saliva profiles in children with congenital heart disease". (2020), 48-54. https://doi.org/10.26650/eor.20200087 |
| APA | KORUYUCU M, Batu S, Bayram M, USLU E, GÜVEN Y, Seymen F (2020). Saliva profiles in children with congenital heart disease. European oral research (Online), 54(1), 48 - 54. 10.26650/eor.20200087 |
| Chicago | KORUYUCU Mine,Batu Sule,Bayram Merve,USLU Ezel,GÜVEN Yegane,Seymen Figen Saliva profiles in children with congenital heart disease. European oral research (Online) 54, no.1 (2020): 48 - 54. 10.26650/eor.20200087 |
| MLA | KORUYUCU Mine,Batu Sule,Bayram Merve,USLU Ezel,GÜVEN Yegane,Seymen Figen Saliva profiles in children with congenital heart disease. European oral research (Online), vol.54, no.1, 2020, ss.48 - 54. 10.26650/eor.20200087 |
| AMA | KORUYUCU M,Batu S,Bayram M,USLU E,GÜVEN Y,Seymen F Saliva profiles in children with congenital heart disease. European oral research (Online). 2020; 54(1): 48 - 54. 10.26650/eor.20200087 |
| Vancouver | KORUYUCU M,Batu S,Bayram M,USLU E,GÜVEN Y,Seymen F Saliva profiles in children with congenital heart disease. European oral research (Online). 2020; 54(1): 48 - 54. 10.26650/eor.20200087 |
| IEEE | KORUYUCU M,Batu S,Bayram M,USLU E,GÜVEN Y,Seymen F "Saliva profiles in children with congenital heart disease." European oral research (Online), 54, ss.48 - 54, 2020. 10.26650/eor.20200087 |
| ISNAD | KORUYUCU, Mine vd. "Saliva profiles in children with congenital heart disease". European oral research (Online) 54/1 (2020), 48-54. https://doi.org/10.26650/eor.20200087 |
