Yıl: 2018 Cilt: 33 Sayı: 2 Sayfa Aralığı: 65 - 72 Metin Dili: İngilizce DOI: 10.5505/tjo.2018.1769 İndeks Tarihi: 18-08-2020

Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation

Öz:
OBJECTIVEIn this study, three-dimensional conformal radiation therapy (3D-CRT), intensity-modulated RT(IMRT), and volumetric-modulated arc therapy (VMAT) techniques were compared in patients withglioblastoma multiforme (GBM) receiving RT. Comparisons were made in terms of sparing the organsat risk (OAR), by using European Organisation for Research and Treatment of Cancer-Advisory Committee on Radiation Oncology Practise (EORTC-ACROP) guideline.METHODSRT in 10 patients was replanned. Treatment volume was created according to the EORTC-ACROP, and60 Gy/30 fraction dose was prescribed for planning target volume (PTV). PTV-less brain volume (BPTV) Dmean, OARs doses; V5Gy and V50Gy of B-PTV volumes; conformality, and homogeneity indices were analyzed.RESULTSB-PTV was spared better in IMRT. The optic chiasm, contralateral optic nerve, ipsilateral/contralateralcochlea were significantly spared in IMRT and VMAT. The best sparing for brainstem, pituitary gland,ipsilateral eye, ipsilateral lacrimal gland was obtained with VMAT. B-PTV volume received at least 5 Gywas similar in three plans, but lower with 50 Gy in IMRT and VMAT (p<0.001). Although homogenousdose distribution was obtained with similar homogeneity index in all three planning techniques, conformity index was the best in VMAT (p<0.001).CONCLUSIONVMAT provides improved conformity index and good homogeneity in GBM RT using the EORTCACROP target and dose definition. The best sparing for OAR was obtained with VMAT.
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APA İBİŞ K, AKBAŞ U, KOKSAL C, altun m (2018). Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation. , 65 - 72. 10.5505/tjo.2018.1769
Chicago İBİŞ Kamuran,AKBAŞ Uğur,KOKSAL CANAN,altun musa Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation. (2018): 65 - 72. 10.5505/tjo.2018.1769
MLA İBİŞ Kamuran,AKBAŞ Uğur,KOKSAL CANAN,altun musa Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation. , 2018, ss.65 - 72. 10.5505/tjo.2018.1769
AMA İBİŞ K,AKBAŞ U,KOKSAL C,altun m Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation. . 2018; 65 - 72. 10.5505/tjo.2018.1769
Vancouver İBİŞ K,AKBAŞ U,KOKSAL C,altun m Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation. . 2018; 65 - 72. 10.5505/tjo.2018.1769
IEEE İBİŞ K,AKBAŞ U,KOKSAL C,altun m "Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation." , ss.65 - 72, 2018. 10.5505/tjo.2018.1769
ISNAD İBİŞ, Kamuran vd. "Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation". (2018), 65-72. https://doi.org/10.5505/tjo.2018.1769
APA İBİŞ K, AKBAŞ U, KOKSAL C, altun m (2018). Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation. Türk Onkoloji Dergisi, 33(2), 65 - 72. 10.5505/tjo.2018.1769
Chicago İBİŞ Kamuran,AKBAŞ Uğur,KOKSAL CANAN,altun musa Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation. Türk Onkoloji Dergisi 33, no.2 (2018): 65 - 72. 10.5505/tjo.2018.1769
MLA İBİŞ Kamuran,AKBAŞ Uğur,KOKSAL CANAN,altun musa Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation. Türk Onkoloji Dergisi, vol.33, no.2, 2018, ss.65 - 72. 10.5505/tjo.2018.1769
AMA İBİŞ K,AKBAŞ U,KOKSAL C,altun m Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation. Türk Onkoloji Dergisi. 2018; 33(2): 65 - 72. 10.5505/tjo.2018.1769
Vancouver İBİŞ K,AKBAŞ U,KOKSAL C,altun m Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation. Türk Onkoloji Dergisi. 2018; 33(2): 65 - 72. 10.5505/tjo.2018.1769
IEEE İBİŞ K,AKBAŞ U,KOKSAL C,altun m "Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation." Türk Onkoloji Dergisi, 33, ss.65 - 72, 2018. 10.5505/tjo.2018.1769
ISNAD İBİŞ, Kamuran vd. "Comparison of Three-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, and Volumetric-Modulated Arc Therapy In Glioblastoma Multiforme Radiation Therapy With EORTC Target Delineation". Türk Onkoloji Dergisi 33/2 (2018), 65-72. https://doi.org/10.5505/tjo.2018.1769