Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test

Yıl: 2019 Cilt: 26 Sayı: 10 Sayfa Aralığı: 2295 - 2298 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2019.08.450 İndeks Tarihi: 21-09-2020

Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test

Öz:
Aim: Evaluating the cognitive functions of patients with relapsing-remitting multiple sclerosis (RRMS) by using the MontrealCognitive Assessment (MoCA) Test.Material and Methods: This cross-sectional study consisted of 28 RRMS patients who were diagnosed based on the revisedMcDonald 2017 criteria and 30 healthy volunteers. The MoCA test and the Expanded Disability Status Scale (EDSS) were applied.Results: The mean age of the RRMS patients was 37.21±5.61, while the mean age of the healthy volunteers was 35.6±10.09(p=0.459). 17 (60.7%) of the RRMS patients were female, 11 (39.3%) were male, while 16 (63.3%) of the control group were female,and 14 (46.7%) were male (p=0.571). The median total MoCA score was 24 (min: 15, max: 30) for the RRMS patients and 27 (min: 19,max: 30) for the healthy volunteers, and the difference was significant (p=0.006). The scores of the RRMS patients were significantlylower in terms of the MoCA sub-dimensions of executive functions, attention, language and delayed recall. There was a negative,medium-level significant correlation between the total MoCA scores and EDSS scores (r: -0.583; p<0.001).Conclusion: The results of this study showed that, in the cognitive dysfunction process in RRMS patients, especially executivefunctions, attention, language and delayed recall are affected, and there is also a relationship between cognitive dysfunction anddisability. Furthermore, these results emphasize the significance of cognitive impairment in RRMS patients and show that the MoCAtest may be a practical test that can be used for cognitive monitoring of RRMS patients.
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APA HAMAMCI M (2019). Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test. , 2295 - 2298. 10.5455/annalsmedres.2019.08.450
Chicago HAMAMCI Mehmet Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test. (2019): 2295 - 2298. 10.5455/annalsmedres.2019.08.450
MLA HAMAMCI Mehmet Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test. , 2019, ss.2295 - 2298. 10.5455/annalsmedres.2019.08.450
AMA HAMAMCI M Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test. . 2019; 2295 - 2298. 10.5455/annalsmedres.2019.08.450
Vancouver HAMAMCI M Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test. . 2019; 2295 - 2298. 10.5455/annalsmedres.2019.08.450
IEEE HAMAMCI M "Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test." , ss.2295 - 2298, 2019. 10.5455/annalsmedres.2019.08.450
ISNAD HAMAMCI, Mehmet. "Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test". (2019), 2295-2298. https://doi.org/10.5455/annalsmedres.2019.08.450
APA HAMAMCI M (2019). Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test. Annals of Medical Research, 26(10), 2295 - 2298. 10.5455/annalsmedres.2019.08.450
Chicago HAMAMCI Mehmet Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test. Annals of Medical Research 26, no.10 (2019): 2295 - 2298. 10.5455/annalsmedres.2019.08.450
MLA HAMAMCI Mehmet Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test. Annals of Medical Research, vol.26, no.10, 2019, ss.2295 - 2298. 10.5455/annalsmedres.2019.08.450
AMA HAMAMCI M Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test. Annals of Medical Research. 2019; 26(10): 2295 - 2298. 10.5455/annalsmedres.2019.08.450
Vancouver HAMAMCI M Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test. Annals of Medical Research. 2019; 26(10): 2295 - 2298. 10.5455/annalsmedres.2019.08.450
IEEE HAMAMCI M "Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test." Annals of Medical Research, 26, ss.2295 - 2298, 2019. 10.5455/annalsmedres.2019.08.450
ISNAD HAMAMCI, Mehmet. "Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test". Annals of Medical Research 26/10 (2019), 2295-2298. https://doi.org/10.5455/annalsmedres.2019.08.450